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Osamu Sugiyama MD, PhD

TitlePostdoctoral Fellow
InstitutionUConn Health Center
DepartmentOrthopaedic Surgery
AddressMC 4037
Medical Arts & Research Building, MC 4037
263 Farmington Avenue
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bougioukli S, Jain A, Sugiyama O, Tinsley BA, Tang AH, Tan MH, Adams DJ, Kostenuik PJ, Lieberman JR. Combination therapy with BMP-2 and a systemic RANKL inhibitor enhances bone healing in a mouse critical-sized femoral defect. Bone. 2016 Mar; 84:93-103. PMID: 26723577.
      View in: PubMed
    2. Pensak M, Hong S, Dukas A, Tinsley B, Drissi H, Tang A, Cote M, Sugiyama O, Lichtler A, Rowe D, Lieberman JR. The role of transduced bone marrow cells overexpressing BMP-2 in healing critical-sized defects in a mouse femur. Gene Ther. 2015 Jun; 22(6):467-75. PMID: 25809463.
      View in: PubMed
    3. Alaee F, Bartholomae C, Sugiyama O, Virk MS, Drissi H, Wu Q, Schmidt M, Lieberman JR. Biodistribution of LV-TSTA transduced rat bone marrow cells used for "ex-vivo" regional gene therapy for bone repair. Curr Gene Ther. 2015; 15(5):481-91. PMID: 26264707.
      View in: PubMed
    4. Alaee F, Sugiyama O, Virk MS, Tang H, Drissi H, Lichtler AC, Lieberman JR. Suicide gene approach using a dual-expression lentiviral vector to enhance the safety of ex vivo gene therapy for bone repair. Gene Ther. 2014 Feb; 21(2):139-47. PMID: 24285218.
      View in: PubMed
    5. Alaee F, Virk MS, Tang H, Sugiyama O, Adams DJ, Stolina M, Dwyer D, Ominsky MS, Ke HZ, Lieberman JR. Evaluation of the effects of systemic treatment with a sclerostin neutralizing antibody on bone repair in a rat femoral defect model. J Orthop Res. 2014 Feb; 32(2):197-203. PMID: 24600701.
      View in: PubMed
    6. Alaee F, Sugiyama O, Virk MS, Tang Y, Wang B, Lieberman JR. In vitro evaluation of a double-stranded self-complementary adeno-associated virus type2 vector in bone marrow stromal cells for bone healing. Genet Vaccines Ther. 2011; 9:4. PMID: 21352585; PMCID: PMC3056728.
    7. Virk MS, Sugiyama O, Park SH, Gambhir SS, Adams DJ, Drissi H, Lieberman JR. "Same day" ex-vivo regional gene therapy: a novel strategy to enhance bone repair. Mol Ther. 2011 May; 19(5):960-8. PMID: 21343916; PMCID: PMC3098640.
    8. Virk MS, Alaee F, Petrigliano FA, Sugiyama O, Chatziioannou AF, Stout D, Dougall WC, Lieberman JR. Combined inhibition of the BMP pathway and the RANK-RANKL axis in a mixed lytic/blastic prostate cancer lesion. Bone. 2011 Mar 1; 48(3):578-87. PMID: 21073986; PMCID: PMC3039095.
    9. Petrigliano FA, Virk MS, Liu N, Sugiyama O, Yu D, Lieberman JR. Targeting of prostate cancer cells by a cytotoxic lentiviral vector containing a prostate stem cell antigen (PSCA) promoter. Prostate. 2009 Sep 15; 69(13):1422-34. PMID: 19489029.
      View in: PubMed
    10. Noh JY, Yasuda S, Sato S, Matsumoto M, Kunii Y, Noguchi Y, Mukasa K, Ito K, Ito K, Sugiyama O, Kobayashi H, Nihojima S, Okazaki M, Yokoyama S. Clinical characteristics of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis caused by antithyroid drugs. J Clin Endocrinol Metab. 2009 Aug; 94(8):2806-11. PMID: 19491223.
      View in: PubMed
    11. Miyazaki M, Sugiyama O, Tow B, Zou J, Morishita Y, Wei F, Napoli A, Sintuu C, Lieberman JR, Wang JC. The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats. J Spinal Disord Tech. 2008 Jul; 21(5):372-9. PMID: 18600149.
      View in: PubMed
    12. Miyazaki M, Sugiyama O, Zou J, Yoon SH, Wei F, Morishita Y, Sintuu C, Virk MS, Lieberman JR, Wang JC. Comparison of lentiviral and adenoviral gene therapy for spinal fusion in rats. Spine (Phila Pa 1976). 2008 Jun 1; 33(13):1410-7. PMID: 18475244.
      View in: PubMed
    13. Virk MS, Conduah A, Park SH, Liu N, Sugiyama O, Cuomo A, Kang C, Lieberman JR. Influence of short-term adenoviral vector and prolonged lentiviral vector mediated bone morphogenetic protein-2 expression on the quality of bone repair in a rat femoral defect model. Bone. 2008 May; 42(5):921-31. PMID: 18295562.
      View in: PubMed
    14. Hsu WK, Sugiyama O, Park SH, Conduah A, Feeley BT, Liu NQ, Krenek L, Virk MS, An DS, Chen IS, Lieberman JR. Lentiviral-mediated BMP-2 gene transfer enhances healing of segmental femoral defects in rats. Bone. 2007 Apr; 40(4):931-8. PMID: 17236835.
      View in: PubMed
    15. Feeley BT, Conduah AH, Sugiyama O, Krenek L, Chen IS, Lieberman JR. In vivo molecular imaging of adenoviral versus lentiviral gene therapy in two bone formation models. J Orthop Res. 2006 Aug; 24(8):1709-21. PMID: 16788987.
      View in: PubMed
    16. Sugiyama O, An DS, Kung SP, Feeley BT, Gamradt S, Liu NQ, Chen IS, Lieberman JR. Lentivirus-mediated gene transfer induces long-term transgene expression of BMP-2 in vitro and new bone formation in vivo. Mol Ther. 2005 Mar; 11(3):390-8. PMID: 15727935.
      View in: PubMed
    17. Sugiyama O, Orimo H, Suzuki S, Yamashita K, Ito H, Shimada T. Bone formation following transplantation of genetically modified primary bone marrow stromal cells. J Orthop Res. 2003 Jul; 21(4):630-7. PMID: 12798062.
      View in: PubMed
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