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Last Name
Institution

David C Steffens MD

TitleProfessor and Chairman
InstitutionUConn Health Center
DepartmentPsychiatry
AddressMC 1410
Building L, MC 1410
263 Farmington Ave
Phone860-679-1587
Fax860-679-1296
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dong HS, Han C, Jeon SW, Yoon S, Jeong HG, Huh YJ, Pae CU, Patkar AA, Steffens DC. Characteristics of neurocognitive functions in mild cognitive impairment with depression. Int Psychogeriatr. 2016 Jul; 28(7):1181-90. PMID: 26960534.
      View in: PubMed
    2. Hybels CF, Pieper CF, Blazer DG, Steffens DC. Heterogeneity in the three-year course of major depression among older adults. Int J Geriatr Psychiatry. 2016 Jul; 31(7):775-82. PMID: 26560634.
      View in: PubMed
    3. Jeon SW, Han C, Lee J, Lim J, Jeong HG, Park MH, Ko YH, Pae CU, Kim SH, Joe SH, Steffens DC. Perspectives on the Happiness of Community-Dwelling Elderly in Korea. Psychiatry Investig. 2016 Jan; 13(1):50-7. PMID: 26766946.
      View in: PubMed
    4. Delbaere K, Valenzuela T, Woodbury A, Davies T, Yeong J, Steffens D, Miles L, Pickett L, Zijlstra GA, Clemson L, Close JC, Howard K, Lord SR. Evaluating the effectiveness of a home-based exercise programme delivered through a tablet computer for preventing falls in older community-dwelling people over 2 years: study protocol for the Standing Tall randomised controlled trial. BMJ Open. 2015; 5(10):e009173. PMID: 26493461; PMCID: PMC4620168.
    5. Xiong GL, Prybol K, Boyle SH, Hall R, Streilein RD, Steffens DC, Krishnan R, Rogers JG, O'Connor CM, Jiang W. Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study. Psychosom Med. 2015 Sep; 77(7):808-15. PMID: 26186432; PMCID: PMC4565768 [Available on 09/01/16].
    6. Steffens DC, Manning KJ, Wu R, Grady JJ, Fortinsky RH, Tennen HA. Methodology and preliminary results from the neurobiology of late-life depression study. Int Psychogeriatr. 2015 Dec; 27(12):1987-97. PMID: 26323208; PMCID: PMC4626260 [Available on 12/01/16].
    7. Zdanys KF, Steffens DC. Sleep Disturbances in the Elderly. Psychiatr Clin North Am. 2015 Dec; 38(4):723-41. PMID: 26600105.
      View in: PubMed
    8. Potter GG, McQuoid DR, Whitson HE, Steffens DC. Physical frailty in late-life depression is associated with deficits in speed-dependent executive functions. Int J Geriatr Psychiatry. 2016 May; 31(5):466-74. PMID: 26313370.
      View in: PubMed
    9. Qiu WQ, Zhu H, Dean M, Liu Z, Vu L, Fan G, Li H, Mwamburi M, Steffens DC, Au R. Amyloid-associated depression and ApoE4 allele: longitudinal follow-up for the development of Alzheimer's disease. Int J Geriatr Psychiatry. 2016 Mar; 31(3):316-22. PMID: 26250797.
      View in: PubMed
    10. Wang L, Chou YH, Potter GG, Steffens DC. Altered Synchronizations among Neural Networks in Geriatric Depression. Biomed Res Int. 2015; 2015:343720. PMID: 26180795; PMCID: PMC4477114.
    11. Hybels CF, Pieper CF, Payne ME, Steffens DC. Late-life Depression Modifies the Association Between Cerebral White Matter Hyperintensities and Functional Decline Among Older Adults. Am J Geriatr Psychiatry. 2016 Jan; 24(1):42-9. PMID: 25863558.
      View in: PubMed
    12. Dzierzewski JM, Potter GG, Jones RN, Rostant OS, Ayotte B, Yang FM, Sachs BC, Feldman BJ, Steffens DC. Cognitive functioning throughout the treatment history of clinical late-life depression. Int J Geriatr Psychiatry. 2015 Oct; 30(10):1076-84. PMID: 25703072; PMCID: PMC4545467 [Available on 10/01/16].
    13. Reuben DB, Alvanzo AA, Ashikaga T, Bogat GA, Callahan CM, Ruffing V, Steffens DC. National Institutes of Health Pathways to Prevention Workshop: the role of opioids in the treatment of chronic pain. Ann Intern Med. 2015 Feb 17; 162(4):295-300. PMID: 25581341.
      View in: PubMed
    14. Riddle M, McQuoid DR, Potter GG, Steffens DC, Taylor WD. Disability but not social support predicts cognitive deterioration in late-life depression. Int Psychogeriatr. 2015 May; 27(5):707-14. PMID: 25475430; PMCID: PMC4385394 [Available on 05/01/16].
    15. Kotagal V, Langa KM, Plassman BL, Fisher GG, Giordani BJ, Wallace RB, Burke JR, Steffens DC, Kabeto M, Albin RL, Foster NL. Factors associated with cognitive evaluations in the United States. Neurology. 2015 Jan 6; 84(1):64-71. PMID: 25428689; PMCID: PMC4336093 [Available on 01/06/16].
    16. Zannas AS, McQuoid DR, Payne ME, MacFall JR, Ashley-Koch A, Steffens DC, Potter GG, Taylor WD. Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age. Am J Psychiatry. 2014 Nov 1; 171(11):1214-21. PMID: 25124854; PMCID: PMC4329281.
    17. Mah L, Binns MA, Steffens DC. Anxiety symptoms in amnestic mild cognitive impairment are associated with medial temporal atrophy and predict conversion to Alzheimer disease. Am J Geriatr Psychiatry. 2015 May; 23(5):466-76. PMID: 25500120; PMCID: PMC4390420 [Available on 05/01/16].
    18. Cummings J, Mintzer J, Brodaty H, Sano M, Banerjee S, Devanand DP, Gauthier S, Howard R, Lanctôt K, Lyketsos CG, Peskind E, Porsteinsson AP, Reich E, Sampaio C, Steffens D, Wortmann M, Zhong K. Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition. Int Psychogeriatr. 2015 Jan; 27(1):7-17. PMID: 25311499; PMCID: PMC4301197.
    19. Potter GG, McQuoid DR, Steffens DC. Appetite loss and neurocognitive deficits in late-life depression. Int J Geriatr Psychiatry. 2015 Jun; 30(6):647-54. PMID: 25315155.
      View in: PubMed
    20. Rubinow MJ, Mahajan G, May W, Overholser JC, Jurjus GJ, Dieter L, Herbst N, Steffens DC, Miguel-Hidalgo JJ, Rajkowska G, Stockmeier CA. Basolateral amygdala volume and cell numbers in major depressive disorder: a postmortem stereological study. Brain Struct Funct. 2016 Jan; 221(1):171-84. PMID: 25287512.
      View in: PubMed
    21. Steffens DC, McQuoid DR, Potter GG. Amnestic mild cognitive impairment and incident dementia and Alzheimer's disease in geriatric depression. Int Psychogeriatr. 2014 Dec; 26(12):2029-36. PMID: 25032667; PMCID: PMC4227924 [Available on 12/01/15].
    22. Jeong HG, Han C, Park MH, Ryu SH, Pae CU, Lee JY, Kim SH, Steffens DC. Influence of the number and severity of somatic symptoms on the severity of depression and suicidality in community-dwelling elders. Asia Pac Psychiatry. 2014 Sep; 6(3):274-83. PMID: 24890651; PMCID: PMC4172496.
    23. Kirwin P, Conroy M, Lyketsos C, Greenwald B, Forester B, deVries C, Ahmed II, Wiechers I, Zdanys K, Steffens D, Reynolds CF. A Call to Restructure Psychiatry General and Subspecialty Training. Acad Psychiatry. 2016 Feb; 40(1):145-8. PMID: 24809688.
      View in: PubMed
    24. Yoon S, Lee Y, Han C, Pae CU, Yoon HK, Patkar AA, Steffens DC, Kim YK. Usefulness of the Patient Health Questionnaire-9 for Korean medical students. Acad Psychiatry. 2014 Dec; 38(6):661-7. PMID: 24804631.
      View in: PubMed
    25. Wen MC, Steffens DC, Chen MK, Zainal NH. Diffusion tensor imaging studies in late-life depression: systematic review and meta-analysis. Int J Geriatr Psychiatry. 2014 Dec; 29(12):1173-84. PMID: 24798480.
      View in: PubMed
    26. Payne ME, McQuoid DR, Steffens DC, Anderson JJ. Elevated brain lesion volumes in older adults who use calcium supplements: a cross-sectional clinical observational study. Br J Nutr. 2014 Jul 28; 112(2):220-7. PMID: 24787048; PMCID: PMC4144340.
    27. Taylor WD, Kudra K, Zhao Z, Steffens DC, MacFall JR. Cingulum bundle white matter lesions influence antidepressant response in late-life depression: a pilot study. J Affect Disord. 2014 Jun; 162:8-11. PMID: 24766997; PMCID: PMC4030539.
    28. Sachs-Ericsson N, Moxley JH, Corsentino E, Rushing NC, Sheffler J, Selby EA, Gotlib I, Steffens DC. Melancholia in later life: late and early onset differences in presentation, course, and dementia risk. Int J Geriatr Psychiatry. 2014 Sep; 29(9):943-51. PMID: 24677247.
      View in: PubMed
    29. Steffens D, Hancock MJ, Maher CG, Williams C, Jensen TS, Latimer J. Does magnetic resonance imaging predict future low back pain? A systematic review. Eur J Pain. 2014 Jul; 18(6):755-65. PMID: 24276945.
      View in: PubMed
    30. Taylor WD, McQuoid DR, Payne ME, Zannas AS, MacFall JR, Steffens DC. Hippocampus atrophy and the longitudinal course of late-life depression. Am J Geriatr Psychiatry. 2014 Dec; 22(12):1504-12. PMID: 24378256; PMCID: PMC4031313 [Available on 12/01/15].
    31. Ribeiz SR, Duran F, Oliveira MC, Bezerra D, Castro CC, Steffens DC, Busatto Filho G, Bottino CM. Structural brain changes as biomarkers and outcome predictors in patients with late-life depression: a cross-sectional and prospective study. PLoS One. 2013; 8(11):e80049. PMID: 24244606; PMCID: PMC3828217.
    32. Potter GG, Madden DJ, Costello MC, Steffens DC. Reduced comparison speed during visual search in late life depression. J Clin Exp Neuropsychol. 2013; 35(10):1060-70. PMID: 24219302; PMCID: PMC3869571.
    33. Aziz R, Steffens DC. What are the causes of late-life depression? Psychiatr Clin North Am. 2013 Dec; 36(4):497-516. PMID: 24229653; PMCID: PMC4084923.
    34. Smoski MJ, LaBar KS, Steffens DC. Relative effectiveness of reappraisal and distraction in regulating emotion in late-life depression. Am J Geriatr Psychiatry. 2014 Sep; 22(9):898-907. PMID: 24021222; PMCID: PMC3949222.
    35. Steffens DC, McQuoid DR, Smoski MJ, Potter GG. Clinical outcomes of older depressed patients with and without comorbid neuroticism. Int Psychogeriatr. 2013 Dec; 25(12):1985-90. PMID: 23941723; PMCID: PMC3830609.
    36. Payne ME, Pierce CW, McQuoid DR, Steffens DC, Anderson JJ. Serum ionized calcium may be related to white matter lesion volumes in older adults: a pilot study. Nutrients. 2013 Jun; 5(6):2192-205. PMID: 23778149; PMCID: PMC3725500.
    37. Banga A, Gyurmey T, Matuskey D, Connor DF, Kaplan RF, Steffens DC. Late-life onset bipolar disorder presenting as a case of pseudo-dementia: a case discussion and review of literature. Yale J Biol Med. 2013 Jun; 86(2):235-44. PMID: 23766743; PMCID: PMC3670442.
    38. Lim J, Oh IK, Han C, Huh YJ, Jung IK, Patkar AA, Steffens DC, Jang BH. Sensitivity of cognitive tests in four cognitive domains in discriminating MDD patients from healthy controls: a meta-analysis. Int Psychogeriatr. 2013 Sep; 25(9):1543-57. PMID: 23725644.
      View in: PubMed
    39. Rushing NC, Sachs-Ericsson N, Steffens DC. Neuropsychological indicators of preclinical Alzheimer's disease among depressed older adults. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2014; 21(1):99-128. PMID: 23659628; PMCID: PMC3836908.
    40. Steffens DC. In our hands: responding to the IOM report on workforce needs for older adults with mental health and substance use disorders. Int Psychogeriatr. 2013 Jul; 25(7):1039-40. PMID: 23635719; PMCID: PMC3725562.
    41. Steffens DC. Exercise for late-life depression? It depends. Lancet. 2013 Jul 6; 382(9886):4-5. PMID: 23643109; PMCID: PMC3758669.
    42. Qiu WW, Lai A, Mon T, Mwamburi M, Taylor W, Rosenzweig J, Kowall N, Stern R, Zhu H, Steffens DC. Angiotensin converting enzyme inhibitors and Alzheimer disease in the presence of the apolipoprotein E4 allele. Am J Geriatr Psychiatry. 2014 Feb; 22(2):177-85. PMID: 23567418; PMCID: PMC3873370.
    43. Barcelos-Ferreira R, Nakano EY, Steffens DC, Bottino CM. Quality of life and physical activity associated to lower prevalence of depression in community-dwelling elderly subjects from Sao Paulo. J Affect Disord. 2013 Sep 5; 150(2):616-22. PMID: 23499164.
      View in: PubMed
    44. Zannas AS, McQuoid DR, Payne ME, Steffens DC, MacFall JR, Ashley-Koch A, Taylor WD. Negative life stress and longitudinal hippocampal volume changes in older adults with and without depression. J Psychiatr Res. 2013 Jun; 47(6):829-34. PMID: 23478048; PMCID: PMC3622849.
    45. Potter GG, Wagner HR, Burke JR, Plassman BL, Welsh-Bohmer KA, Steffens DC. Neuropsychological predictors of dementia in late-life major depressive disorder. Am J Geriatr Psychiatry. 2013 Mar; 21(3):297-306. PMID: 23395197; PMCID: PMC3376682.
    46. Sachs-Ericsson N, Hames JL, Joiner TE, Corsentino E, Rushing NC, Palmer E, Gotlib IH, Selby EA, Zarit S, Steffens DC. Differences between suicide attempters and nonattempters in depressed older patients: depression severity, white-matter lesions, and cognitive functioning. Am J Geriatr Psychiatry. 2014 Jan; 22(1):75-85. PMID: 23933424; PMCID: PMC4155401.
    47. Hayward RD, Taylor WD, Smoski MJ, Steffens DC, Payne ME. Association of five-factor model personality domains and facets with presence, onset, and treatment outcomes of major depression in older adults. Am J Geriatr Psychiatry. 2013 Jan; 21(1):88-96. PMID: 23290206; PMCID: PMC3382026.
    48. Jamerson BD, Payne ME, Garrett ME, Ashley-Koch AE, Speer MC, Steffens DC. Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression. Int J Geriatr Psychiatry. 2013 Sep; 28(9):925-32. PMID: 23280573; PMCID: PMC3779127.
    49. Miguel-Hidalgo JJ, Jiang W, Konick L, Overholser JC, Jurjus GJ, Stockmeier CA, Steffens DC, Krishnan KR, Rajkowska G. Morphometric analysis of vascular pathology in the orbitofrontal cortex of older subjects with major depression. Int J Geriatr Psychiatry. 2013 Sep; 28(9):959-70. PMID: 23208772; PMCID: PMC3679255.
    50. Payne ME, Steck SE, George RR, Steffens DC. Fruit, vegetable, and antioxidant intakes are lower in older adults with depression. J Acad Nutr Diet. 2012 Dec; 112(12):2022-7. PMID: 23174689; PMCID: PMC3520090.
    51. Whitson HE, Whitaker D, Sanders LL, Potter GG, Cousins SW, Ansah D, McConnell E, Pieper CF, Landerman L, Steffens DC, Cohen HJ. Memory deficit associated with worse functional trajectories in older adults in low-vision rehabilitation for macular disease. J Am Geriatr Soc. 2012 Nov; 60(11):2087-92. PMID: 23126548; PMCID: PMC3498592.
    52. Rushing NC, Corsentino E, Hames JL, Sachs-Ericsson N, Steffens DC. The relationship of religious involvement indicators and social support to current and past suicidality among depressed older adults. Aging Ment Health. 2013; 17(3):366-74. PMID: 23121118; PMCID: PMC3596433.
    53. Sheline YI, Disabato BM, Hranilovich J, Morris C, D'Angelo G, Pieper C, Toffanin T, Taylor WD, MacFall JR, Wilkins C, Barch DM, Welsh-Bohmer KA, Steffens DC, Krishnan RR, Doraiswamy PM. Treatment course with antidepressant therapy in late-life depression. Am J Psychiatry. 2012 Nov; 169(11):1185-93. PMID: 23534057; PMCID: PMC3752387.
    54. Tschanz JT, Pfister R, Wanzek J, Corcoran C, Smith K, Tschanz BT, Steffens DC, Østbye T, Welsh-Bohmer KA, Norton MC. Stressful life events and cognitive decline in late life: moderation by education and age. The Cache County Study. Int J Geriatr Psychiatry. 2013 Aug; 28(8):821-30. PMID: 23037866; PMCID: PMC3706540.
    55. Ribeiz SR, Ávila R, Martins CB, Moscoso MA, Steffens DC, Bottino CM. Validation of a treatment algorithm for major depression in an older Brazilian sample. Int J Geriatr Psychiatry. 2013 Jun; 28(6):647-53. PMID: 23015472.
      View in: PubMed
    56. Sachs-Ericsson N, Corsentino E, Moxley J, Hames JL, Rushing NC, Sawyer K, Joiner T, Selby EA, Zarit S, Gotlib IH, Steffens DC. A longitudinal study of differences in late- and early-onset geriatric depression: depressive symptoms and psychosocial, cognitive, and neurological functioning. Aging Ment Health. 2013; 17(1):1-11. PMID: 22934752; PMCID: PMC3535510.
    57. Wang L, Potter GG, Krishnan RK, Dolcos F, Smith GS, Steffens DC. Neural correlates associated with cognitive decline in late-life depression. Am J Geriatr Psychiatry. 2012 Aug; 20(8):653-63. PMID: 22157280; PMCID: PMC3337345.
    58. Sachs-Ericsson N, Selby E, Corsentino E, Collins N, Sawyer K, Hames J, Arce D, Joiner T, Steffens DC. Depressed older patients with the atypical features of interpersonal rejection sensitivity and reversed-vegetative symptoms are similar to younger atypical patients. Am J Geriatr Psychiatry. 2012 Jul; 20(7):622-34. PMID: 21997599; PMCID: PMC3374907.
    59. Steffens DC. Depressive symptoms and mild cognitive impairment in the elderly: an ominous combination. Biol Psychiatry. 2012 May 1; 71(9):762-4. PMID: 22482885; PMCID: PMC3337633.
    60. Hayward RD, Owen AD, Koenig HG, Steffens DC, Payne ME. Longitudinal relationships of religion with posttreatment depression severity in older psychiatric patients: evidence of direct and indirect effects. Depress Res Treat. 2012; 2012:745970. PMID: 22461982; PMCID: PMC3296163.
    61. Chiu PY, Steffens D, Chen PK, Hsu YC, Huang HT, Lai TJ. Depression in Taiwanese patients with Alzheimer's disease determined by the National Institutes of Mental Health Provisional Criteria. Int Psychogeriatr. 2012 Aug; 24(8):1299-305. PMID: 22333495.
      View in: PubMed
    62. Hayward RD, Owen AD, Koenig HG, Steffens DC, Payne ME. Religion and the presence and severity of depression in older adults. Am J Geriatr Psychiatry. 2012 Feb; 20(2):188-92. PMID: 22273738; PMCID: PMC3266521.
    63. Wang L, Ashley-Koch A, Steffens DC, Krishnan KR, Taylor WD. Impact of BDNF Val66Met and 5-HTTLPR polymorphism variants on neural substrates related to sadness and executive function. Genes Brain Behav. 2012 Apr; 11(3):352-9. PMID: 22225729; PMCID: PMC3654542.
    64. Potter GG, McQuoid DR, Payne ME, Taylor WD, Steffens DC. Association of attentional shift and reversal learning to functional deficits in geriatric depression. Int J Geriatr Psychiatry. 2012 Nov; 27(11):1172-9. PMID: 22271429; PMCID: PMC3866797.
    65. Zannas AS, McQuoid DR, Steffens DC, Chrousos GP, Taylor WD. Stressful life events, perceived stress, and 12-month course of geriatric depression: direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms. Stress. 2012 Jul; 15(4):425-34. PMID: 22044241; PMCID: PMC3319482.
    66. Sawyer K, Corsentino E, Sachs-Ericsson N, Steffens DC. Depression, hippocampal volume changes, and cognitive decline in a clinical sample of older depressed outpatients and non-depressed controls. Aging Ment Health. 2012; 16(6):753-62. PMID: 22548411; PMCID: PMC3430833.
    67. Lee CT, Leoutsakos JM, Lyketsos CG, Steffens DC, Breitner JC, Norton MC. Latent class-derived subgroups of depressive symptoms in a community sample of older adults: the Cache County Study. Int J Geriatr Psychiatry. 2012 Oct; 27(10):1061-9. PMID: 22135008; PMCID: PMC3419796.
    68. Jiang W, Oken H, Fiuzat M, Shaw LK, Martsberger C, Kuchibhatla M, Kaddurah-Daouk R, Steffens DC, Baillie R, Cuffe M, Krishnan R, O'Connor C. Plasma omega-3 polyunsaturated fatty acids and survival in patients with chronic heart failure and major depressive disorder. J Cardiovasc Transl Res. 2012 Feb; 5(1):92-9. PMID: 22042636.
      View in: PubMed
    69. Taylor WD, Zhao Z, Ashley-Koch A, Payne ME, Steffens DC, Krishnan RR, Hauser E, MacFall JR. Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype. Hum Brain Mapp. 2013 Feb; 34(2):295-303. PMID: 22021115; PMCID: PMC3772522.
    70. Barcelos-Ferreira R, Lopes MA, Nakano EY, Steffens DC, Bottino CM. Clinical and sociodemographic factors in a sample of older subjects experiencing depressive symptoms. Int J Geriatr Psychiatry. 2012 Sep; 27(9):924-30. PMID: 21989903.
      View in: PubMed
    71. Whitson HE, Ansah D, Sanders LL, Whitaker D, Potter GG, Cousins SW, Steffens DC, Landerman LR, Pieper CF, Cohen HJ. Comorbid cognitive impairment and functional trajectories in low vision rehabilitation for macular disease. Aging Clin Exp Res. 2011 Oct-Dec; 23(5-6):343-50. PMID: 22526069; PMCID: PMC3338208.
    72. Burke J, McQuoid DR, Payne ME, Steffens DC, Krishnan RR, Taylor WD. Amygdala volume in late-life depression: relationship with age of onset. Am J Geriatr Psychiatry. 2011 Sep; 19(9):771-6. PMID: 21873832; PMCID: PMC3164525.
    73. Norton MC, Smith KR, Østbye T, Tschanz JT, Schwartz S, Corcoran C, Breitner JC, Steffens DC, Skoog I, Rabins PV, Welsh-Bohmer KA. Early parental death and remarriage of widowed parents as risk factors for Alzheimer disease: the Cache County study. Am J Geriatr Psychiatry. 2011 Sep; 19(9):814-24. PMID: 21873837; PMCID: PMC3164808.
    74. Steffens DC, Taylor WD, Denny KL, Bergman SR, Wang L. Structural integrity of the uncinate fasciculus and resting state functional connectivity of the ventral prefrontal cortex in late life depression. PLoS One. 2011; 6(7):e22697. PMID: 21799934; PMCID: PMC3142185.
    75. Benjamin S, Steffens DC. Structural neuroimaging of geriatric depression. Psychiatr Clin North Am. 2011 Jun; 34(2):423-35, ix. PMID: 21536166; PMCID: PMC3746760.
    76. Alalade E, Denny K, Potter G, Steffens D, Wang L. Altered cerebellar-cerebral functional connectivity in geriatric depression. PLoS One. 2011; 6(5):e20035. PMID: 21637831; PMCID: PMC3102667.
    77. Chang CC, Yu SC, McQuoid DR, Messer DF, Taylor WD, Singh K, Boyd BD, Krishnan KR, MacFall JR, Steffens DC, Payne ME. Reduction of dorsolateral prefrontal cortex gray matter in late-life depression. Psychiatry Res. 2011 Jul 30; 193(1):1-6. PMID: 21596532; PMCID: PMC3105213.
    78. Owen AD, Hayward RD, Koenig HG, Steffens DC, Payne ME. Religious factors and hippocampal atrophy in late life. PLoS One. 2011; 6(3):e17006. PMID: 21479219; PMCID: PMC3068149.
    79. Plassman BL, Langa KM, McCammon RJ, Fisher GG, Potter GG, Burke JR, Steffens DC, Foster NL, Giordani B, Unverzagt FW, Welsh-Bohmer KA, Heeringa SG, Weir DR, Wallace RB. Incidence of dementia and cognitive impairment, not dementia in the United States. Ann Neurol. 2011 Sep; 70(3):418-26. PMID: 21425187; PMCID: PMC3139807.
    80. Dickinson WJ, Potter GG, Hybels CF, McQuoid DR, Steffens DC. Change in stress and social support as predictors of cognitive decline in older adults with and without depression. Int J Geriatr Psychiatry. 2011 Dec; 26(12):1267-74. PMID: 21370277; PMCID: PMC3280427.
    81. Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM. Neuropsychiatric symptoms and the risk of institutionalization and death: the aging, demographics, and memory study. J Am Geriatr Soc. 2011 Mar; 59(3):473-81. PMID: 21391937; PMCID: PMC3088883.
    82. Oddone CG, Hybels CF, McQuoid DR, Steffens DC. Social support modifies the relationship between personality and depressive symptoms in older adults. Am J Geriatr Psychiatry. 2011 Feb; 19(2):123-31. PMID: 21328795; PMCID: PMC3059603.
    83. Hybels CF, Blazer DG, Landerman LR, Steffens DC. Heterogeneity in symptom profiles among older adults diagnosed with major depression. Int Psychogeriatr. 2011 Aug; 23(6):906-22. PMID: 21241529; PMCID: PMC3139722.
    84. Sachs-Erisson N, Sawyer K, Corsentino E, Collins N, Steffens DC. The moderating effect of the APOE [small element of] 4 allele on the relationship between hippocampal volume and cognitive decline in older depressed patients. Am J Geriatr Psychiatry. 2011 Jan; 19(1):23-32. PMID: 21218563; PMCID: PMC3057467.
    85. Steffens DC, McQuoid DR, Payne ME, Potter GG. Change in hippocampal volume on magnetic resonance imaging and cognitive decline among older depressed and nondepressed subjects in the neurocognitive outcomes of depression in the elderly study. Am J Geriatr Psychiatry. 2011 Jan; 19(1):4-12. PMID: 20808107; PMCID: PMC3010251.
    86. Culang-Reinlieb ME, Johnert LC, Brickman AM, Steffens DC, Garcon E, Sneed JR. MRI-defined vascular depression: a review of the construct. Int J Geriatr Psychiatry. 2011 Nov; 26(11):1101-8. PMID: 21192018.
      View in: PubMed
    87. Isamah N, Faison W, Payne ME, MacFall J, Steffens DC, Beyer JL, Krishnan KR, Taylor WD. Variability in frontotemporal brain structure: the importance of recruitment of African Americans in neuroscience research. PLoS One. 2010; 5(10):e13642. PMID: 21049028; PMCID: PMC2964318.
    88. Zhang X, Nicholls PJ, Laje G, Sotnikova TD, Gainetdinov RR, Albert PR, Rajkowska G, Stockmeier CA, Speer MC, Steffens DC, Austin MC, McMahon FJ, Krishnan KR, Garcia-Blanco MA, Caron MG. A functional alternative splicing mutation in human tryptophan hydroxylase-2. Mol Psychiatry. 2011 Dec; 16(12):1169-76. PMID: 20856248; PMCID: PMC3021090.
    89. Steffens DC, Nelson JC, Eudicone JM, Andersson C, Yang H, Tran QV, Forbes RA, Carlson BX, Berman RM. Efficacy and safety of adjunctive aripiprazole in major depressive disorder in older patients: a pooled subpopulation analysis. Int J Geriatr Psychiatry. 2011 Jun; 26(6):564-72. PMID: 20827794; PMCID: PMC3709840.
    90. Smith PJ, Blumenthal JA, Babyak MA, Watkins LL, Hinderliter A, Hoffman BM, Steffens DC, Sherwood A, Doraiswamy PM. Cerebrovascular risk factors and cerebral hyperintensities among middle-aged and older adults with major depression. Am J Geriatr Psychiatry. 2010 Sep; 18(9):848-52. PMID: 20808104; PMCID: PMC3075070.
    91. Lee JJ, Kim KW, Kim TH, Park JH, Lee SB, Park JW, McQuoid DR, Steffens DC. Cross-cultural considerations in administering the center for epidemiologic studies depression scale. Gerontology. 2011; 57(5):455-61. PMID: 20720392; PMCID: PMC3180654.
    92. Marquine MJ, Attix DK, Goldstein LB, Samsa GP, Payne ME, Chelune GJ, Steffens DC. Differential patterns of cognitive decline in anterior and posterior white matter hyperintensity progression. Stroke. 2010 Sep; 41(9):1946-50. PMID: 20651266; PMCID: PMC3279727.
    93. Grangeon MC, Seixas C, Quarantini LC, Miranda-Scippa A, Pompili M, Steffens DC, Wenzel A, Lacerda AL, de Oliveira IR. White matter hyperintensities and their association with suicidality in major affective disorders: a meta-analysis of magnetic resonance imaging studies. CNS Spectr. 2010 Jun; 15(6):375-81. PMID: 20625370; PMCID: PMC2976664.
    94. Naylor JC, Kilts JD, Hulette CM, Steffens DC, Blazer DG, Ervin JF, Strauss JL, Allen TB, Massing MW, Payne VM, Youssef NA, Shampine LJ, Marx CE. Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects. Biochim Biophys Acta. 2010 Aug; 1801(8):951-9. PMID: 20488256; PMCID: PMC2907131.
    95. Barcelos-Ferreira R, Izbicki R, Steffens DC, Bottino CM. Depressive morbidity and gender in community-dwelling Brazilian elderly: systematic review and meta-analysis. Int Psychogeriatr. 2010 Aug; 22(5):712-26. PMID: 20478096.
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    96. Norton MC, Smith KR, Østbye T, Tschanz JT, Corcoran C, Schwartz S, Piercy KW, Rabins PV, Steffens DC, Skoog I, Breitner JC, Welsh-Bohmer KA. Greater risk of dementia when spouse has dementia? The Cache County study. J Am Geriatr Soc. 2010 May; 58(5):895-900. PMID: 20722820; PMCID: PMC2945313.
    97. Ribeiz SR, Bassitt DP, Arrais JA, Avila R, Steffens DC, Bottino CM. Cholinesterase inhibitors as adjunctive therapy in patients with schizophrenia and schizoaffective disorder: a review and meta-analysis of the literature. CNS Drugs. 2010 Apr; 24(4):303-17. PMID: 20297855.
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    98. Benjamin S, McQuoid DR, Potter GG, Payne ME, MacFall JR, Steffens DC, Taylor WD. The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression. Am J Geriatr Psychiatry. 2010 Apr; 18(4):323-31. PMID: 20220593; PMCID: PMC2928477.
    99. Pae CU, Sohi MS, Seo HJ, Serretti A, Patkar AA, Steffens DC, Masand PS. Quetiapine XR: current status for the treatment of major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1; 34(7):1165-73. PMID: 20307622.
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    100. Taylor WD, McQuoid DR, Ashley-Koch A, MacFall JR, Bridgers J, Krishnan RR, Steffens DC. BDNF Val66Met genotype and 6-month remission rates in late-life depression. Pharmacogenomics J. 2011 Apr; 11(2):146-54. PMID: 20195291; PMCID: PMC2962689.
    101. Sheline YI, Pieper CF, Barch DM, Welsh-Bohmer K, Welsh-Boehmer K, McKinstry RC, MacFall JR, D'Angelo G, Garcia KS, Gersing K, Wilkins C, Taylor W, Steffens DC, Krishnan RR, Doraiswamy PM. Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial. Arch Gen Psychiatry. 2010 Mar; 67(3):277-85. PMID: 20194828; PMCID: PMC2838210.
    102. Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM. Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study. J Am Geriatr Soc. 2010 Feb; 58(2):330-7. PMID: 20374406; PMCID: PMC2875937.
    103. Steffens DC. Metabolomic differences in heart failure patients with and without major depression. J Geriatr Psychiatry Neurol. 2010 Jun; 23(2):138-46. PMID: 20101071; PMCID: PMC3279728.
    104. Steffens DC. Imaging and genetics advances in understanding geriatric depression. Neuropsychopharmacology. 2010 Jan; 35(1):349-50. PMID: 20010715; PMCID: PMC3055442.
    105. Hybels CF, Pieper CF, Blazer DG, Fillenbaum GG, Steffens DC. Trajectories of mobility and IADL function in older patients diagnosed with major depression. Int J Geriatr Psychiatry. 2010 Jan; 25(1):74-81. PMID: 19548209; PMCID: PMC2894462.
    106. Calakos N, Patel VD, Gottron M, Wang G, Tran-Viet KN, Brewington D, Beyer JL, Steffens DC, Krishnan RR, Züchner S. Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia. J Med Genet. 2010 Sep; 47(9):646-50. PMID: 19955557; PMCID: PMC2891583.
    107. Potter GG, Plassman BL, Burke JR, Kabeto MU, Langa KM, Llewellyn DJ, Rogers MA, Steffens DC. Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites. Alzheimers Dement. 2009 Nov; 5(6):445-53. PMID: 19896583; PMCID: PMC2805266.
    108. Steffens DC. A multiplicity of approaches to characterize geriatric depression and its outcomes. Curr Opin Psychiatry. 2009 Nov; 22(6):522-6. PMID: 19625967; PMCID: PMC2833219.
    109. Hong ED, Taylor WD, McQuoid DR, Potter GG, Payne ME, Ashley-Koch A, Steffens DC. Influence of the MTHFR C677T polymorphism on magnetic resonance imaging hyperintensity volume and cognition in geriatric depression. Am J Geriatr Psychiatry. 2009 Oct; 17(10):847-55. PMID: 19910873; PMCID: PMC2805265.
    110. Payne ME, Jamerson BD, Potocky CF, Ashley-Koch AE, Speer MC, Steffens DC. Natural food folate and late-life depression. J Nutr Elder. 2009 Oct; 28(4):348-58. PMID: 21184377; PMCID: PMC3324853.
    111. Potter GG, Taylor WD, McQuoid DR, Steffens DC, Welsh-Bohmer KA, Krishnan KR. The COMT Val158Met polymorphism and cognition in depressed and nondepressed older adults. Int J Geriatr Psychiatry. 2009 Oct; 24(10):1127-33. PMID: 19296553; PMCID: PMC3793427.
    112. Ayotte BJ, Potter GG, Williams HT, Steffens DC, Bosworth HB. The moderating role of personality factors in the relationship between depression and neuropsychological functioning among older adults. Int J Geriatr Psychiatry. 2009 Sep; 24(9):1010-9. PMID: 19226526; PMCID: PMC2730210.
    113. Pan CC, McQuoid DR, Taylor WD, Payne ME, Ashley-Koch A, Steffens DC. Association analysis of the COMT/MTHFR genes and geriatric depression: an MRI study of the putamen. Int J Geriatr Psychiatry. 2009 Aug; 24(8):847-55. PMID: 19235787; PMCID: PMC2711996.
    114. Van Otterloo E, O'Dwyer G, Stockmeier CA, Steffens DC, Krishnan RR, Rajkowska G. Reductions in neuronal density in elderly depressed are region specific. Int J Geriatr Psychiatry. 2009 Aug; 24(8):856-64. PMID: 19405038; PMCID: PMC2756775.
    115. Barcelos-Ferreira R, Pinto JA, Nakano EY, Steffens DC, Litvoc J, Bottino CM. Clinically significant depressive symptoms and associated factors in community elderly subjects from Sao Paulo, Brazil. Am J Geriatr Psychiatry. 2009 Jul; 17(7):582-90. PMID: 19546654.
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    117. Pae CU, Mandelli L, Han C, Ham BJ, Masand PS, Patkar AA, Steffens DC, De Ronchi D, Serretti A. Thyroid hormones affect recovery from depression during antidepressant treatment. Psychiatry Clin Neurosci. 2009 Jun; 63(3):305-13. PMID: 19566761.
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    118. Whitson HE, Ansah D, Whitaker D, Potter G, Cousins SW, MacDonald H, Pieper CF, Landerman L, Steffens DC, Cohen HJ. Prevalence and patterns of comorbid cognitive impairment in low vision rehabilitation for macular disease. Arch Gerontol Geriatr. 2010 Mar-Apr; 50(2):209-12. PMID: 19427045; PMCID: PMC2815114.
    119. Hybels CF, Blazer DG, Pieper CF, Landerman LR, Steffens DC. Profiles of depressive symptoms in older adults diagnosed with major depression: latent cluster analysis. Am J Geriatr Psychiatry. 2009 May; 17(5):387-96. PMID: 19390296; PMCID: PMC2718569.
    120. Wang CS, Burke JR, Steffens DC, Hulette CM, Breitner JC, Plassman BL. Twin pairs discordant for neuropathologically confirmed Lewy body dementia. J Neurol Neurosurg Psychiatry. 2009 May; 80(5):562-5. PMID: 19372291; PMCID: PMC2758029.
    121. Venkatraman TN, Krishnan RR, Steffens DC, Song AW, Taylor WD. Biochemical abnormalities of the medial temporal lobe and medial prefrontal cortex in late-life depression. Psychiatry Res. 2009 Apr 30; 172(1):49-54. PMID: 19179054; PMCID: PMC2659332.
    122. Taylor WD, Steffens DC, Ashley-Koch A, Payne ME, MacFall JR, Potocky CF, Krishnan KR. Angiotensin receptor gene polymorphisms and 2-year change in hyperintense lesion volume in men. Mol Psychiatry. 2010 Aug; 15(8):816-22. PMID: 19274051; PMCID: PMC2891956.
    123. Potter GG, McQuoid DR, Steffens DC, Welsh-Bohmer KA, Krishnan KR. Neuropsychological correlates of magnetic resonance imaging-defined subcortical ischemic depression. Int J Geriatr Psychiatry. 2009 Mar; 24(3):219-25. PMID: 18655212; PMCID: PMC2645482.
    124. Steffens DC, McQuoid DR, Potter GG. Outcomes of older cognitively impaired individuals with current and past depression in the NCODE study. J Geriatr Psychiatry Neurol. 2009 Mar; 22(1):52-61. PMID: 19196631; PMCID: PMC2745319.
    125. Trone RJ, Weaver KG, Steffens DC, Payne ME. Glycemic index and glycemic load are not associated with brain lesions in the elderly. J Nutr Health Aging. 2009 Feb; 13(2):117-20. PMID: 19214339; PMCID: PMC2850063.
    126. Züchner S, Wendland JR, Ashley-Koch AE, Collins AL, Tran-Viet KN, Quinn K, Timpano KC, Cuccaro ML, Pericak-Vance MA, Steffens DC, Krishnan KR, Feng G, Murphy DL. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. Mol Psychiatry. 2009 Jan; 14(1):6-9. PMID: 19096451; PMCID: PMC2803344.
    127. Pae CU, Marks DM, Han C, Patkar AA, Steffens D. Does neurotropin-3 have a therapeutic implication in major depression? Int J Neurosci. 2008 Nov; 118(11):1515-22. PMID: 18853330.
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    128. Qiu A, Taylor WD, Zhao Z, MacFall JR, Miller MI, Key CR, Payne ME, Steffens DC, Krishnan KR. APOE related hippocampal shape alteration in geriatric depression. Neuroimage. 2009 Feb 1; 44(3):620-6. PMID: 19010425; PMCID: PMC2648826.
    129. Taylor WD, Züchner S, McQuoid DR, Steffens DC, Blazer DG, Krishnan KR. Social support in older individuals: the role of the BDNF Val66Met polymorphism. Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5; 147B(7):1205-12. PMID: 18384075; PMCID: PMC2575229.
    130. Carlson MC, Helms MJ, Steffens DC, Burke JR, Potter GG, Plassman BL. Midlife activity predicts risk of dementia in older male twin pairs. Alzheimers Dement. 2008 Sep; 4(5):324-31. PMID: 18790459; PMCID: PMC3673771.
    131. Story TJ, Potter GG, Attix DK, Welsh-Bohmer KA, Steffens DC. Neurocognitive correlates of response to treatment in late-life depression. Am J Geriatr Psychiatry. 2008 Sep; 16(9):752-9. PMID: 18697883; PMCID: PMC2722450.
    132. Steffens DC. Separating mood disturbance from mild cognitive impairment in geriatric depression. Int Rev Psychiatry. 2008 Aug; 20(4):374-81. PMID: 18925486.
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    133. Pae CU, Mandelli L, Han C, Ham BJ, Masand PS, Patkar AA, Steffens DC, De Ronchi D, Serretti A. Do estradiol levels influence on the cognitive function during antidepressant treatments in post-menopausal women with major depressive disorder? A comparison with pre-menopausal women. Neuro Endocrinol Lett. 2008 Aug; 29(4):500-6. PMID: 18766158.
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    134. Cukrowicz KC, Duberstein PR, Vannoy SD, Lynch TR, McQuoid DR, Steffens DC. Course of suicide ideation and predictors of change in depressed older adults. J Affect Disord. 2009 Feb; 113(1-2):30-6. PMID: 18617271; PMCID: PMC2673909.
    135. Greenberg DL, Payne ME, MacFall JR, Steffens DC, Krishnan RR. Hippocampal volumes and depression subtypes. Psychiatry Res. 2008 Jul 15; 163(2):126-32. PMID: 18508244; PMCID: PMC2486434.
    136. Sneed JR, Rindskopf D, Steffens DC, Krishnan KR, Roose SP. The vascular depression subtype: evidence of internal validity. Biol Psychiatry. 2008 Sep 15; 64(6):491-7. PMID: 18490003; PMCID: PMC2597784.
    137. Naylor JC, Hulette CM, Steffens DC, Shampine LJ, Ervin JF, Payne VM, Massing MW, Kilts JD, Strauss JL, Calhoun PS, Calnaido RP, Blazer DG, Lieberman JA, Madison RD, Marx CE. Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage. J Clin Endocrinol Metab. 2008 Aug; 93(8):3173-8. PMID: 18477662; PMCID: PMC2515081.
    138. Payne ME, Anderson JJ, Steffens DC. Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders. Nutr Res. 2008 May; 28(5):285-92. PMID: 19083421; PMCID: PMC2516961.
    139. Wang L, Krishnan KR, Steffens DC, Potter GG, Dolcos F, McCarthy G. Depressive state- and disease-related alterations in neural responses to affective and executive challenges in geriatric depression. Am J Psychiatry. 2008 Jul; 165(7):863-71. PMID: 18450929.
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    140. Sun X, Steffens DC, Au R, Folstein M, Summergrad P, Yee J, Rosenberg I, Mwamburi DM, Qiu WQ. Amyloid-associated depression: a prodromal depression of Alzheimer disease? Arch Gen Psychiatry. 2008 May; 65(5):542-50. PMID: 18458206; PMCID: PMC3042807.
    141. Norton MC, Singh A, Skoog I, Corcoran C, Tschanz JT, Zandi PP, Breitner JC, Welsh-Bohmer KA, Steffens DC. Church attendance and new episodes of major depression in a community study of older adults: the Cache County Study. J Gerontol B Psychol Sci Soc Sci. 2008 May; 63(3):P129-37. PMID: 18559677; PMCID: PMC2673327.
    142. Pae CU, Mandelli L, Kim TS, Han C, Masand PS, Marks DM, Patkar AA, Steffens DC, De Ronchi D, Serretti A. Effectiveness of antidepressant treatments in pre-menopausal versus post-menopausal women: a pilot study on differential effects of sex hormones on antidepressant effects. Biomed Pharmacother. 2009 Mar; 63(3):228-35. PMID: 18502089.
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    143. Doty TJ, Payne ME, Steffens DC, Beyer JL, Krishnan KR, LaBar KS. Age-dependent reduction of amygdala volume in bipolar disorder. Psychiatry Res. 2008 May 30; 163(1):84-94. PMID: 18407469; PMCID: PMC2483539.
    144. Hybels CF, Pieper CF, Blazer DG, Steffens DC. The course of depressive symptoms in older adults with comorbid major depression and dysthymia. Am J Geriatr Psychiatry. 2008 Apr; 16(4):300-9. PMID: 18378555.
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    145. Zhao Z, Taylor WD, Styner M, Steffens DC, Krishnan KR, MacFall JR. Hippocampus shape analysis and late-life depression. PLoS One. 2008; 3(3):e1837. PMID: 18350172; PMCID: PMC2265542.
    146. Plassman BL, Langa KM, Fisher GG, Heeringa SG, Weir DR, Ofstedal MB, Burke JR, Hurd MD, Potter GG, Rodgers WL, Steffens DC, McArdle JJ, Willis RJ, Wallace RB. Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med. 2008 Mar 18; 148(6):427-34. PMID: 18347351; PMCID: PMC2670458.
    147. Steffens DC, Taylor WD, McQuoid DR, Krishnan KR. Short/long heterozygotes at 5HTTLPR and white matter lesions in geriatric depression. Int J Geriatr Psychiatry. 2008 Mar; 23(3):244-8. PMID: 17702053.
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    148. Taylor WD, Züchner S, McQuoid DR, Payne ME, MacFall JR, Steffens DC, Speer MC, Krishnan KR. The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression. Am J Geriatr Psychiatry. 2008 Apr; 16(4):263-71. PMID: 18263664.
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    149. Steinberg M, Shao H, Zandi P, Lyketsos CG, Welsh-Bohmer KA, Norton MC, Breitner JC, Steffens DC, Tschanz JT. Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry. 2008 Feb; 23(2):170-7. PMID: 17607801; PMCID: PMC2932652.
    150. Bosworth HB, Voils CI, Potter GG, Steffens DC. The effects of antidepressant medication adherence as well as psychosocial and clinical factors on depression outcome among older adults. Int J Geriatr Psychiatry. 2008 Feb; 23(2):129-34. PMID: 17563920.
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    151. Steffens DC, Chung H, Krishnan KR, Longstreth WT, Carlson M, Burke GL. Antidepressant treatment and worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study. Stroke. 2008 Mar; 39(3):857-62. PMID: 18239166.
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    152. Thakur M, Grossman I, McCrory DC, Orlando LA, Steffens DC, Cline KE, Gray RN, Farmer J, DeJesus G, O'Brien C, Samsa G, Goldstein DB, Matchar DB. Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors. Genet Med. 2007 Dec; 9(12):826-35. PMID: 18091432.
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    153. Plassman BL, Langa KM, Fisher GG, Heeringa SG, Weir DR, Ofstedal MB, Burke JR, Hurd MD, Potter GG, Rodgers WL, Steffens DC, Willis RJ, Wallace RB. Prevalence of dementia in the United States: the aging, demographics, and memory study. Neuroepidemiology. 2007; 29(1-2):125-32. PMID: 17975326; PMCID: PMC2705925.
    154. Han C, Jo SA, Kwak JH, Pae CU, Steffens D, Jo I, Park MH. Validation of the Patient Health Questionnaire-9 Korean version in the elderly population: the Ansan Geriatric study. Compr Psychiatry. 2008 Mar-Apr; 49(2):218-23. PMID: 18243897.
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    155. Pae CU, Lim HK, Han C, Patkar AA, Steffens DC, Masand PS, Lee C. Fatigue as a core symptom in major depressive disorder: overview and the role of bupropion. Expert Rev Neurother. 2007 Oct; 7(10):1251-63. PMID: 17939764.
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    156. Taylor WD, Züchner S, McQuoid DR, Steffens DC, Speer MC, Krishnan KR. Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. Am J Geriatr Psychiatry. 2007 Oct; 15(10):850-7. PMID: 17911362.
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    157. Kim JJ, Mandelli L, Pae CU, De Ronchi D, Jun TY, Lee C, Paik IH, Patkar AA, Steffens D, Serretti A, Han C. Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15; 32(2):375-9. PMID: 17964051.
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    159. Potter GG, Helms MJ, Burke JR, Steffens DC, Plassman BL. Job demands and dementia risk among male twin pairs. Alzheimers Dement. 2007 Jul; 3(3):192-9. PMID: 18591984.
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    160. Kondo DG, Speer MC, Krishnan KR, McQuoid DR, Slifer SH, Pieper CF, Billups AV, Steffens DC. Association of AGTR1 with 18-month treatment outcome in late-life depression. Am J Geriatr Psychiatry. 2007 Jul; 15(7):564-72. PMID: 17586781.
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    161. Steffens DC, Stechuchak KM, Oddone EZ. How asymptomatic is asymptomatic carotid stenosis? Radiology. 2007 Jul; 244(1):317-8, author reply 318-9. PMID: 17581914.
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    162. Steffens DC. Spiritual considerations in suicide and depression among the elderly. South Med J. 2007 Jul; 100(7):748-9. PMID: 17639767.
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    163. Steffens DC, Potter GG. Geriatric depression and cognitive impairment. Psychol Med. 2008 Feb; 38(2):163-75. PMID: 17588275.
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    164. Taylor WD, Bae JN, MacFall JR, Payne ME, Provenzale JM, Steffens DC, Krishnan KR. Widespread effects of hyperintense lesions on cerebral white matter structure. AJR Am J Roentgenol. 2007 Jun; 188(6):1695-704. PMID: 17515396.
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    165. Potter GG, Steffens DC. Contribution of depression to cognitive impairment and dementia in older adults. Neurologist. 2007 May; 13(3):105-17. PMID: 17495754.
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    166. Paige LA, Mitchell MW, Krishnan KR, Kaddurah-Daouk R, Steffens DC. A preliminary metabolomic analysis of older adults with and without depression. Int J Geriatr Psychiatry. 2007 May; 22(5):418-23. PMID: 17048218.
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    167. Sun C, Tikellis G, Klein R, Steffens DC, Larsen EK, Wong TY. Depressive symptoms and age-related macular degeneration in older people: the cardiovascular health study. Ophthalmic Epidemiol. 2007 May-Jun; 14(3):127-33. PMID: 17613847.
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    168. Voils CI, Allaire JC, Olsen MK, Steffens DC, Hoyle RH, Bosworth HB. Five-year trajectories of social networks and social support in older adults with major depression. Int Psychogeriatr. 2007 Dec; 19(6):1110-24. PMID: 17433120.
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    169. Sun C, Tikellis G, Klein R, Steffens DC, Larsen EK, Siscovick DS, Klein BE, Wong TY. Are microvascular abnormalities in the retina associated with depression symptoms? The Cardiovascular Health Study. Am J Geriatr Psychiatry. 2007 Apr; 15(4):335-43. PMID: 17384316.
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    170. Taylor WD, Macfall JR, Payne ME, McQuoid DR, Steffens DC, Provenzale JM, Krishnan KR. Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. Psychol Med. 2007 Dec; 37(12):1763-73. PMID: 17335636.
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    172. Young AJ, Johnson S, Steffens DC, Doraiswamy PM. Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 2007 Jan; 12(1):62-8. PMID: 17192765.
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    173. Matchar DB, Thakur ME, Grossman I, McCrory DC, Orlando LA, Steffens DC, Goldstein DB, Cline KE, Gray RN. Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs). Evid Rep Technol Assess (Full Rep). 2007 Jan; (146):1-77. PMID: 17764209.
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    174. Hannestad J, Taylor WD, McQuoid DR, Payne ME, Krishnan KR, Steffens DC, Macfall JR. White matter lesion volumes and caudate volumes in late-life depression. Int J Geriatr Psychiatry. 2006 Dec; 21(12):1193-8. PMID: 16955447.
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    175. Plassman BL, Steffens DC, Burke JR, Welsh-Bohmer KA, Newman TN, Drosdick D, Helms MJ, Potter GG, Breitner JC. Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry. Twin Res Hum Genet. 2006 Dec; 9(6):950-7. PMID: 17254435.
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    176. Xiong GL, Plassman BL, Helms MJ, Steffens DC. Vascular risk factors and cognitive decline among elderly male twins. Neurology. 2006 Nov 14; 67(9):1586-91. PMID: 17101888.
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    177. Payne ME, Haines PS, Chambless LE, Anderson JJ, Steffens DC. Food group intake and brain lesions in late-life vascular depression. Int Psychogeriatr. 2007 Apr; 19(2):295-305. PMID: 17054820.
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    178. Greenberg DL, Messer DF, Payne ME, Macfall JR, Provenzale JM, Steffens DC, Krishnan RR. Aging, gender, and the elderly adult brain: an examination of analytical strategies. Neurobiol Aging. 2008 Feb; 29(2):290-302. PMID: 17049410; PMCID: PMC2694568.
    179. Taylor WD, Steffens DC, Krishnan KR. Psychiatric disease in the twenty-first century: The case for subcortical ischemic depression. Biol Psychiatry. 2006 Dec 15; 60(12):1299-303. PMID: 17014829.
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    180. Unützer J, Tang L, Oishi S, Katon W, Williams JW, Hunkeler E, Hendrie H, Lin EH, Levine S, Grypma L, Steffens DC, Fields J, Langston C. Reducing suicidal ideation in depressed older primary care patients. J Am Geriatr Soc. 2006 Oct; 54(10):1550-6. PMID: 17038073.
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    181. Marx CE, Trost WT, Shampine LJ, Stevens RD, Hulette CM, Steffens DC, Ervin JF, Butterfield MI, Blazer DG, Massing MW, Lieberman JA. The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease. Biol Psychiatry. 2006 Dec 15; 60(12):1287-94. PMID: 16997284.
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    279. Steffens DC, Norton MC, Plassman BL, Tschanz JT, Wyse BW, Welsh-Bohmer KA, Anthony JC, Breitner JC. Enhanced cognitive performance with estrogen use in nondemented community-dwelling older women. J Am Geriatr Soc. 1999 Oct; 47(10):1171-5. PMID: 10522948.
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    280. Breitner JC, Wyse BW, Anthony JC, Welsh-Bohmer KA, Steffens DC, Norton MC, Tschanz JT, Plassman BL, Meyer MR, Skoog I, Khachaturian A. APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study. Neurology. 1999 Jul 22; 53(2):321-31. PMID: 10430421.
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    281. Steffens DC, O'Connor CM, Jiang WJ, Pieper CF, Kuchibhatla MN, Arias RM, Look A, Davenport C, Gonzalez MB, Krishnan KR. The effect of major depression on functional status in patients with coronary artery disease. J Am Geriatr Soc. 1999 Mar; 47(3):319-22. PMID: 10078894.
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    282. Steffens DC, Hays JC, Krishnan KR. Disability in geriatric depression. Am J Geriatr Psychiatry. 1999; 7(1):34-40. PMID: 9919318.
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    283. Ahearn EP, Steffens DC, Cassidy F, Van Meter SA, Provenzale JM, Seldin MF, Weisler RH, Krishnan KR. Familial leukoencephalopathy in bipolar disorder. Am J Psychiatry. 1998 Nov; 155(11):1605-7. PMID: 9812127.
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    284. Doraiswamy PM, Steffens DC. Combination therapy for early Alzheimer's disease: what are we waiting for? J Am Geriatr Soc. 1998 Oct; 46(10):1322-4. PMID: 9777922.
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    285. Steffens DC, Tupler LA, Ranga K, Krishnan R. Magnetic resonance imaging signal hypointensity and iron content of putamen nuclei in elderly depressed patients. Psychiatry Res. 1998 Aug 26; 83(2):95-103. PMID: 9818735.
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    286. Meyer MR, Tschanz JT, Norton MC, Welsh-Bohmer KA, Steffens DC, Wyse BW, Breitner JC. APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease. Nat Genet. 1998 Aug; 19(4):321-2. PMID: 9697689.
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    287. Steffens DC, Krishnan KR. Structural neuroimaging and mood disorders: recent findings, implications for classification, and future directions. Biol Psychiatry. 1998 May 15; 43(10):705-12. PMID: 9606523.
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    288. Krystal AD, Watts BV, Weiner RD, Moore S, Steffens DC, Lindahl V. The use of flumazenil in the anxious and benzodiazepine-dependent ECT patient. J ECT. 1998 Mar; 14(1):5-14. PMID: 9661088.
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    289. Steffens DC, Rama Krishnan KR. Psychotherapeutic agents in older adults. Metabolism, bioavailability, and drug interactions. Clin Geriatr Med. 1998 Feb; 14(1):17-31. PMID: 9456333.
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    290. Doraiswamy PM, Steffens DC, Pitchumoni S, Tabrizi S. Early recognition of Alzheimer's disease: what is consensual? What is controversial? What is practical? J Clin Psychiatry. 1998; 59 Suppl 13:6-18. PMID: 9771825.
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    291. Steffens DC, Artigues DL, Ornstein KA, Krishnan KR. A review of racial differences in geriatric depression: implications for care and clinical research. J Natl Med Assoc. 1997 Nov; 89(11):731-6. PMID: 9375477; PMCID: PMC2608282.
    292. Rossmanith WG, Steffens D, Schramm G. A comparative randomized trial on the impact of two low-dose oral contraceptives on ovarian activity, cervical permeability, and endometrial receptivity. Contraception. 1997 Jul; 56(1):23-30. PMID: 9306028.
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    293. Steffens DC, Plassman BL, Helms MJ, Welsh-Bohmer KA, Saunders AM, Breitner JC. A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease. Biol Psychiatry. 1997 Apr 15; 41(8):851-6. PMID: 9099411.
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    294. Steffens DC, Krishnan KR, Helms MJ. Are SSRIs better than TCAs? Comparison of SSRIs and TCAs: a meta-analysis. Depress Anxiety. 1997; 6(1):10-8. PMID: 9394870.
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    295. Steffens DC, McDonald WM, Tupler LA, Boyko OB, Krishnan KR. Magnetic resonance imaging changes in putamen nuclei iron content and distribution in normal subjects. Psychiatry Res. 1996 Nov 25; 68(1):55-61. PMID: 9027933.
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    296. Steffens DC, Hays JC, George LK, Krishnan KR, Blazer DG. Sociodemographic and clinical correlates of number of previous depressive episodes in the depressed elderly. J Affect Disord. 1996 Jul 8; 39(2):99-106. PMID: 8827418.
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    297. Steffens DC, Krishnan KR. Decision model for the acute treatment of mania. Depress Anxiety. 1996-1997; 4(6):289-93. PMID: 9166657.
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    298. Breitner JC, Welsh KA, Gau BA, McDonald WM, Steffens DC, Saunders AM, Magruder KM, Helms MJ, Plassman BL, Folstein MF, et al. Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance. Arch Neurol. 1995 Aug; 52(8):763-71. PMID: 7639628.
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    299. Jerrett JG, Steffens DC. Carbon monoxide-related organic mood disorder successfully treated with ECT. J Clin Psychiatry. 1995 Jul; 56(7):332-3. PMID: 7615491.
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    300. Muly EC, McDonald W, Steffens D, Book S. Serotonin syndrome produced by a combination of fluoxetine and lithium. Am J Psychiatry. 1993 Oct; 150(10):1565. PMID: 8379573.
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