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Pamela R Tessier MS

TitleResearch Supervisor
InstitutionHartford Hospital
DepartmentCenter for Anti-Infective Research and Development
Address80 Seymour Street
Phone860-545-4407
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. O'Dowd H, Shannon DE, Chandupatla KR, Dixit V, Engtrakul JJ, Ye Z, Jones SM, O'Brien CF, Nicolau DP, Tessier PR, Crandon JL, Song B, Macikenas D, Hanzelka BL, Le Tiran A, Bennani YL, Charifson PS, Grillot AL. Discovery and Characterization of a Water-Soluble Prodrug of a Dual Inhibitor of Bacterial DNA Gyrase and Topoisomerase IV. ACS Med Chem Lett. 2015 Jul 9; 6(7):822-6. PMID: 26191374; PMCID: PMC4499827 [Available on 07/09/16].
    2. Perola E, Stamos D, Grillot AL, Ronkin S, Wang T, LeTiran A, Tang Q, Deininger DD, Liao Y, Tian SK, Drumm JE, Nicolau DP, Tessier PR, Mani N, Grossman TH, Charifson PS. Successful application of serum shift prediction models to the design of dual targeting inhibitors of bacterial gyrase B and topoisomerase IV with improved in vivo efficacy. Bioorg Med Chem Lett. 2014 May 1; 24(9):2177-81. PMID: 24685546.
      View in: PubMed
    3. Tessier PR, Nicolau DP. In vitro activity of novel gyrase inhibitors against a highly resistant population of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2013 Jun; 57(6):2887-9. PMID: 23571537; PMCID: PMC3716190.
    4. Tessier PR, Nicolau DP. Tigecycline displays in vivo bactericidal activity against extended-spectrum-ß-lactamase-producing Enterobacteriaceae after 72-hour exposure period. Antimicrob Agents Chemother. 2013 Jan; 57(1):640-2. PMID: 23114764; PMCID: PMC3535914.
    5. Tessier PR, Keel RA, Hagihara M, Crandon JL, Nicolau DP. Comparative in vivo efficacies of epithelial lining fluid exposures of tedizolid, linezolid, and vancomycin for methicillin-resistant Staphylococcus aureus in a mouse pneumonia model. Antimicrob Agents Chemother. 2012 May; 56(5):2342-6. PMID: 22354302; PMCID: PMC3346598.
    6. Housman ST, Tessier PR, Nicolau DP, Kuti JL. Physical compatibility of telavancin hydrochloride with select i.v. drugs during simulated Y-site administration. Am J Health Syst Pharm. 2011 Dec 1; 68(23):2265-70. PMID: 22095816.
      View in: PubMed
    7. Bulik CC, Tessier PR, Keel RA, Sutherland CA, Nicolau DP. In vivo comparison of CXA-101 (FR264205) with and without tazobactam versus piperacillin-tazobactam using human simulated exposures against phenotypically diverse gram-negative organisms. Antimicrob Agents Chemother. 2012 Jan; 56(1):544-9. PMID: 22064538; PMCID: PMC3256089.
    8. Rodvold KA, Nicolau DP, Lodise TP, Khashab M, Noel GJ, Kahn JB, Gotfried M, Murray SA, Nicholson S, Laohavaleeson S, Tessier PR, Drusano GL. Identifying exposure targets for treatment of staphylococcal pneumonia with ceftobiprole. Antimicrob Agents Chemother. 2009 Aug; 53(8):3294-301. PMID: 19451287; PMCID: PMC2715607.
    9. Nicasio AM, Tessier PR, Nicolau DP, Knauft RF, Russomanno J, Shore E, Kuti JL. Bronchopulmonary disposition of micafungin in healthy adult volunteers. Antimicrob Agents Chemother. 2009 Mar; 53(3):1218-20. PMID: 19114675; PMCID: PMC2650581.
    10. Charifson PS, Grillot AL, Grossman TH, Parsons JD, Badia M, Bellon S, Deininger DD, Drumm JE, Gross CH, LeTiran A, Liao Y, Mani N, Nicolau DP, Perola E, Ronkin S, Shannon D, Swenson LL, Tang Q, Tessier PR, Tian SK, Trudeau M, Wang T, Wei Y, Zhang H, Stamos D. Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationships. J Med Chem. 2008 Sep 11; 51(17):5243-63. PMID: 18690678.
      View in: PubMed
    11. Laohavaleeson S, Tessier PR, Nicolau DP. Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. Antimicrob Agents Chemother. 2008 Jul; 52(7):2389-94. PMID: 18411322; PMCID: PMC2443930.
    12. Lee SY, Tessier PR, Murphy CK, Nicolau DP. Bactericidal efficacy of ABI-0043, a novel rifamycin, in a murine pneumococcal pneumonia model. J Antibiot (Tokyo). 2006 Dec; 59(12):804-7. PMID: 17323649.
      View in: PubMed
    13. Ong CT, Tessier PR, Li C, Nightingale CH, Nicolau DP. Comparative in vivo efficacy of meropenem, imipenem, and cefepime against Pseudomonas aeruginosa expressing MexA-MexB-OprM efflux pumps. Diagn Microbiol Infect Dis. 2007 Feb; 57(2):153-61. PMID: 16930925.
      View in: PubMed
    14. Dandekar PK, Tessier PR, Farrell DJ, Nightingale CH, Nicolau DP. Evaluation of telithromycin against Streptococcus pneumoniae with ribosomal mutations utilizing in vitro time-kill methodology. Int J Antimicrob Agents. 2005 Oct; 26(4):331-4. PMID: 16144757.
      View in: PubMed
    15. Dandekar PK, Williams P, Tessier PR, Farrell DJ, Nightingale CH, Nicolau DP. Assessment of the efficacy of telithromycin simulating human exposures against S. pneumoniae with ribosomal mutations in a murine pneumonia model. Int J Antimicrob Agents. 2005 Jun; 25(6):530-4. PMID: 15894464.
      View in: PubMed
    16. Tessier PR, Mattoes HM, Dandekar PK, Nightingale CH, Nicolau DP. Pharmacodynamic profile of telithromycin against macrolide- and fluoroquinolone-resistant Streptococcus pneumoniae in a neutropenic mouse thigh model. Antimicrob Agents Chemother. 2005 Jan; 49(1):188-94. PMID: 15616295; PMCID: PMC538883.
    17. Maglio D, Capitano B, Banevicius MA, Tessier PR, Nightingale CH, Nicolau DP. Efficacy of clarithromycin against Streptococcus pneumoniae expressing mef(A)-mediated resistance. Int J Antimicrob Agents. 2004 May; 23(5):498-501. PMID: 15120730.
      View in: PubMed
    18. Dandekar PK, Tessier PR, Williams P, Zhang C, Nightingale CH, Nicolau DP. Determination of the pharmacodynamic profile of daptomycin against Streptococcus pneumoniae isolates with varying susceptibility to penicillin in a murine thigh infection model. Chemotherapy. 2004 Apr; 50(1):11-6. PMID: 15084799.
      View in: PubMed
    19. Florea NR, Tessier PR, Zhang C, Nightingale CH, Nicolau DP. Pharmacodynamics of moxifloxacin and levofloxacin at simulated epithelial lining fluid drug concentrations against Streptococcus pneumoniae. Antimicrob Agents Chemother. 2004 Apr; 48(4):1215-21. PMID: 15047522; PMCID: PMC375308.
    20. Dandekar PK, Tessier PR, Williams P, Nightingale CH, Nicolau DP. Pharmacodynamic profile of daptomycin against Enterococcus species and methicillin-resistant Staphylococcus aureus in a murine thigh infection model. J Antimicrob Chemother. 2003 Sep; 52(3):405-11. PMID: 12917254.
      View in: PubMed
    21. Tessier PR. Interscience Conference on Antimicrobial Agents and Chemotherapy--42nd meeting. Investigational drugs. 27-30 September 2002, San Diego, CA, USA. IDrugs. 2002 Nov; 5(11):1033-5. PMID: 14649641.
      View in: PubMed
    22. Kim MK, Zhou W, Tessier PR, Xuan D, Ye M, Nightingale CH, Nicolau DP. Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. Antimicrob Agents Chemother. 2002 Oct; 46(10):3185-92. PMID: 12234843; PMCID: PMC128791.
    23. Tessier PR, Kim MK, Zhou W, Xuan D, Li C, Ye M, Nightingale CH, Nicolau DP. Pharmacodynamic assessment of clarithromycin in a murine model of pneumococcal pneumonia. Antimicrob Agents Chemother. 2002 May; 46(5):1425-34. PMID: 11959578; PMCID: PMC127127.
    24. Tessier P. American Society of Microbiology - 101st General Meeting. Vaccines and antifungals. 20-24 May 2001, Orlando, FL, USA. IDrugs. 2001 Aug; 4(8):908-10. PMID: 15973587.
      View in: PubMed
    25. Tessier PR, Nicolau DP, Onyeji CO, Nightingale CH. Pharmacodynamics of intermittent- and continuous-infusion cefepime alone and in combination with once-daily tobramycin against Pseudomonas aeruginosa in an in vitro infection model. Chemotherapy. 1999 Jul-Aug; 45(4):284-95. PMID: 10394012.
      View in: PubMed
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