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Syam Prasad Nukavarapu PhD

TitleAssistant Professor
InstitutionUConn Health Center
DepartmentOrthopaedic Surgery
AddressMC 3711
MC 3711
263 Farmington Avenue
Phone860-679-4183
Fax860-679-1553
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    Other Positions
    TitleAssistant Professor
    InstitutionUniversity of Connecticut
    DepartmentChemical, Materials and Biomolecular Engineering

    TitleAssistant Professor
    InstitutionUConn Health Center
    DepartmentInstitute for Regenerative Engineering


    Collapse Overview 
    Collapse overview
    Dr. Nukavarapu received his Ph.D. in Materials Science from the Indian Institute of Science, India. He later held post doctoral positions in the Department of Materials Science and Engineering, Lehigh University and the department of Orthopedic Surgery, University of Virginia (UVA), Charlottesville, Virginia. During the stay at UVA, Dr. Nukavarapu developed novel biodegradable scaffolds and characterized them for bone tissue engineering applications. He recently joined the University of Connecticut where he is an assistant professor in the Department of Orthopaedic Surgery and the Department of Chemical, Materials, and Biomolecular Engineering. His research interests include orthopaedic biomaterials and tissue engineering.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Amini AR, Xu TO, Chidambaram RM, Nukavarapu SP. Oxygen Tension-Controlled Matrices with Osteogenic and Vasculogenic Cells for Vascularized Bone Regeneration In Vivo. Tissue Eng Part A. 2016 Apr; 22(7-8):610-20. PMID: 26914219.
      View in: PubMed
    2. Majumdar S, Pothirajan P, Dorcemus D, Nukavarapu S, Kotecha M. Erratum to: High Field Sodium MRI Assessment of Stem Cell Chondrogenesis in a Tissue-Engineered Matrix. Ann Biomed Eng. 2016 Mar; 44(3):833. PMID: 26795975.
      View in: PubMed
    3. Majumdar S, Pothirajan P, Dorcemus D, Nukavarapu S, Kotecha M. High Field Sodium MRI Assessment of Stem Cell Chondrogenesis in a Tissue-Engineered Matrix. Ann Biomed Eng. 2016 Apr; 44(4):1120-7. PMID: 26168719.
      View in: PubMed
    4. Mikael PE, Amini AR, Basu J, Josefina Arellano-Jimenez M, Laurencin CT, Sanders MM, Barry Carter C, Nukavarapu SP. Functionalized carbon nanotube reinforced scaffolds for bone regenerative engineering: fabrication, in vitro and in vivo evaluation. Biomed Mater. 2014 Jun; 9(3):035001. PMID: 24687391.
      View in: PubMed
    5. Amini AR, Nukavarapu SP. Oxygen-tension controlled matrices for enhanced osteogenic cell survival and performance. Ann Biomed Eng. 2014 Jun; 42(6):1261-70. PMID: 24570389.
      View in: PubMed
    6. Mikael PE, Xin X, Urso M, Jiang X, Wang L, Barnes B, Lichtler AC, Rowe DW, Nukavarapu SP. A potential translational approach for bone tissue engineering through endochondral ossification. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:3925-8. PMID: 25570850.
      View in: PubMed
    7. Pothirajan P, Dorcemus D, Nukavarapu S, Kotecha M. True MRI assessment of stem cell chondrogenesis in a tissue engineered matrix. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:3933-6. PMID: 25570852.
      View in: PubMed
    8. Nukavarapu SP, Dorcemus DL. Osteochondral tissue engineering: current strategies and challenges. Biotechnol Adv. 2013 Sep-Oct; 31(5):706-21. PMID: 23174560.
      View in: PubMed
    9. Igwe JC, Mikael PE, Nukavarapu SP. Design, fabrication and in vitro evaluation of a novel polymer-hydrogel hybrid scaffold for bone tissue engineering. J Tissue Eng Regen Med. 2014 Feb; 8(2):131-42. PMID: 22689304.
      View in: PubMed
    10. Amini AR, Adams DJ, Laurencin CT, Nukavarapu SP. Optimally porous and biomechanically compatible scaffolds for large-area bone regeneration. Tissue Eng Part A. 2012 Jul; 18(13-14):1376-88. PMID: 22401817.
      View in: PubMed
    11. Amini AR, Laurencin CT, Nukavarapu SP. Differential analysis of peripheral blood- and bone marrow-derived endothelial progenitor cells for enhanced vascularization in bone tissue engineering. J Orthop Res. 2012 Sep; 30(9):1507-15. PMID: 22378621.
      View in: PubMed
    12. Amini AR, Laurencin CT, Nukavarapu SP. Bone tissue engineering: recent advances and challenges. Crit Rev Biomed Eng. 2012; 40(5):363-408. PMID: 23339648; PMCID: PMC3766369.
    13. Nukavarapu SP, Amini AR. Optimal scaffold design and effective progenitor cell identification for the regeneration of vascularized bone. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:2464-7. PMID: 22254840.
      View in: PubMed
    14. Amini AR, Wallace JS, Nukavarapu SP. Short-term and long-term effects of orthopedic biodegradable implants. J Long Term Eff Med Implants. 2011; 21(2):93-122. PMID: 22043969; PMCID: PMC3470866.
    15. Taylor ED, Nair LS, Nukavarapu SP, McLaughlin S, Laurencin CT. Novel nanostructured scaffolds as therapeutic replacement options for rotator cuff disease. J Bone Joint Surg Am. 2010 Dec; 92 Suppl 2:170-9. PMID: 21123600; PMCID: PMC2995583.
    16. Deng M, Nair LS, Nukavarapu SP, Jiang T, Kanner WA, Li X, Kumbar SG, Weikel AL, Krogman NR, Allcock HR, Laurencin CT. Dipeptide-based polyphosphazene and polyester blends for bone tissue engineering. Biomaterials. 2010 Jun; 31(18):4898-908. PMID: 20334909; PMCID: PMC2856749.
    17. Jiang T, Nukavarapu SP, Deng M, Jabbarzadeh E, Kofron MD, Doty SB, Abdel-Fattah WI, Laurencin CT. Chitosan-poly(lactide-co-glycolide) microsphere-based scaffolds for bone tissue engineering: in vitro degradation and in vivo bone regeneration studies. Acta Biomater. 2010 Sep; 6(9):3457-70. PMID: 20307694.
      View in: PubMed
    18. Deng M, Nair LS, Nukavarapu SP, Kumbar SG, Brown JL, Krogman NR, Weikel AL, Allcock HR, Laurencin CT. Biomimetic, bioactive etheric polyphosphazene-poly(lactide-co-glycolide) blends for bone tissue engineering. J Biomed Mater Res A. 2010 Jan; 92(1):114-25. PMID: 19165780.
      View in: PubMed
    19. Krogman NR, Weikel AL, Kristhart KA, Nukavarapu SP, Deng M, Nair LS, Laurencin CT, Allcock HR. The influence of side group modification in polyphosphazenes on hydrolysis and cell adhesion of blends with PLGA. Biomaterials. 2009 Jun; 30(17):3035-41. PMID: 19345410; PMCID: PMC2693372.
    20. Laurencin CT, Kumbar SG, Nukavarapu SP. Nanotechnology and orthopedics: a personal perspective. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Jan-Feb; 1(1):6-10. PMID: 20049774.
      View in: PubMed
    21. Kumbar SG, James R, Nukavarapu SP, Laurencin CT. Electrospun nanofiber scaffolds: engineering soft tissues. Biomed Mater. 2008 Sep; 3(3):034002. PMID: 18689924.
      View in: PubMed
    22. Kumbar SG, Nukavarapu SP, James R, Nair LS, Laurencin CT. Electrospun poly(lactic acid-co-glycolic acid) scaffolds for skin tissue engineering. Biomaterials. 2008 Oct; 29(30):4100-7. PMID: 18639927; PMCID: PMC2605109.
    23. Nukavarapu SP, Kumbar SG, Brown JL, Krogman NR, Weikel AL, Hindenlang MD, Nair LS, Allcock HR, Laurencin CT. Polyphosphazene/nano-hydroxyapatite composite microsphere scaffolds for bone tissue engineering. Biomacromolecules. 2008 Jul; 9(7):1818-25. PMID: 18517248; PMCID: PMC2746952.
    24. Deng M, Nair LS, Nukavarapu SP, Kumbar SG, Jiang T, Krogman NR, Singh A, Allcock HR, Laurencin CT. Miscibility and in vitro osteocompatibility of biodegradable blends of poly[(ethyl alanato) (p-phenyl phenoxy) phosphazene] and poly(lactic acid-glycolic acid). Biomaterials. 2008 Jan; 29(3):337-49. PMID: 17942150; PMCID: PMC2129129.
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