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Peter Benn PhD

TitleProfessor
InstitutionUConn Health Center
DepartmentGenetics and Developmental Biology
AddressMC 6140
MC 6140
263 Farmington Avenue
Phone860-679-3614
Fax860-679-3616
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Benn P, Chapman AR. Ethical and practical challenges in providing noninvasive prenatal testing for chromosome abnormalities: an update. Curr Opin Obstet Gynecol. 2016 Apr; 28(2):119-24. PMID: 26938150.
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    2. Benn P. Posttest risk calculation following positive noninvasive prenatal screening using cell-free DNA in maternal plasma. Am J Obstet Gynecol. 2016 Jun; 214(6):676.e1-7. PMID: 26772793.
      View in: PubMed
    3. Gross SJ, Stosic M, McDonald-McGinn DM, Bassett AS, Norvez A, Dhamankar R, Kobara K, Kirkizlar E, Zimmermann B, Wayham N, Babiarz JE, Ryan A, Jinnett KN, Demko Z, Benn P. Clinical experience with single-nucleotide polymorphism-based non-invasive prenatal screening for 22q11.2 deletion syndrome. Ultrasound Obstet Gynecol. 2016 Feb; 47(2):177-83. PMID: 26396068.
      View in: PubMed
    4. Rose NC, Benn P, Milunsky A. Current controversies in prenatal diagnosis 1: should NIPT routinely include microdeletions/microduplications? Prenat Diagn. 2016 Jan; 36(1):10-4. PMID: 26492631.
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    5. Benn P, Curnow KJ, Chapman S, Michalopoulos SN, Hornberger J, Rabinowitz M. An Economic Analysis of Cell-Free DNA Non-Invasive Prenatal Testing in the US General Pregnancy Population. PLoS One. 2015; 10(7):e0132313. PMID: 26158465; PMCID: PMC4497716.
    6. Dar P, Gross SJ, Benn P. Positive predictive values and false-positive results in noninvasive prenatal screening. Am J Obstet Gynecol. 2015 Oct; 213(4):595-6. PMID: 26070701.
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    7. Benn P, Borrell A, Chiu RW, Cuckle H, Dugoff L, Faas B, Gross S, Huang T, Johnson J, Maymon R, Norton M, Odibo A, Schielen P, Spencer K, Wright D, Yaron Y. Position statement from the Chromosome Abnormality Screening Committee on behalf of the Board of the International Society for Prenatal Diagnosis. Prenat Diagn. 2015 Aug; 35(8):725-34. PMID: 25970088.
      View in: PubMed
    8. Gross SJ, Ryan A, Benn P. Noninvasive prenatal testing for 22q11.2 deletion syndrome: deeper sequencing increases the positive predictive value. Am J Obstet Gynecol. 2015 Aug; 213(2):254-5. PMID: 25986033.
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    9. Dar P, Gross SJ, Benn P. Reply: To PMID 25111587. Am J Obstet Gynecol. 2015 Aug; 213(2):253-4. PMID: 25940611.
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    10. Benn P. Re: Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146?958 pregnancies. H. Zhang, Y. Gao, F. Jiang, M. Fu, Y. Yuan, Y. Guo, Z. Zhu, M. Lin, Q. Liu, Z. Tian, H. Zhang, F. Chen, T. K. Lau, L. Zhao, X. Yi, Y. Yin and W. Wang. Ultrasound Obstet Gynecol 2015; 45: 530-538. Ultrasound Obstet Gynecol. 2015 May; 45(5):512-3. PMID: 25914392.
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    11. Cuckle H, Benn P, Pergament E. Cell-free DNA screening for fetal aneuploidy as a clinical service. Clin Biochem. 2015 Oct; 48(15):932-41. PMID: 25732593.
      View in: PubMed
    12. Langlois S, Benn P, Wilkins-Haug L. Current controversies in prenatal diagnosis 4: pre-conception expanded carrier screening should replace all current prenatal screening for specific single gene disorders. Prenat Diagn. 2015 Jan; 35(1):23-8. PMID: 25395388.
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    13. Wapner RJ, Babiarz JE, Levy B, Stosic M, Zimmermann B, Sigurjonsson S, Wayham N, Ryan A, Banjevic M, Lacroute P, Hu J, Hall MP, Demko Z, Siddiqui A, Rabinowitz M, Gross SJ, Hill M, Benn P. Expanding the scope of noninvasive prenatal testing: detection of fetal microdeletion syndromes. Am J Obstet Gynecol. 2015 Mar; 212(3):332.e1-9. PMID: 25479548.
      View in: PubMed
    14. Dar P, Curnow KJ, Gross SJ, Hall MP, Stosic M, Demko Z, Zimmermann B, Hill M, Sigurjonsson S, Ryan A, Banjevic M, Kolacki PL, Koch SW, Strom CM, Rabinowitz M, Benn P. Clinical experience and follow-up with large scale single-nucleotide polymorphism-based noninvasive prenatal aneuploidy testing. Am J Obstet Gynecol. 2014 Nov; 211(5):527.e1-527.e17. PMID: 25111587.
      View in: PubMed
    15. Benn P. Non-Invasive Prenatal Testing Using Cell Free DNA in Maternal Plasma: Recent Developments and Future Prospects. J Clin Med. 2014; 3(2):537-65. PMID: 26237390; PMCID: PMC4449688.
    16. Gurram P, Benn P, Grady J, Prabulos AM, Campbell W. First Trimester Aneuploidy Screening Markers in Women with Pre-Gestational Diabetes Mellitus. J Clin Med. 2014; 3(2):480-90. PMID: 26237386; PMCID: PMC4449679.
    17. Benn P, Cuckle H. Theoretical performance of non-invasive prenatal testing for chromosome imbalances using counting of cell-free DNA fragments in maternal plasma. Prenat Diagn. 2014 Aug; 34(8):778-83. PMID: 24676912.
      View in: PubMed
    18. Benn P, Chapman AR, Erickson K, Defrancesco MS, Wilkins-Haug L, Egan JF, Schulkin J. Obstetricians and gynecologists' practice and opinions of expanded carrier testing and noninvasive prenatal testing. Prenat Diagn. 2014 Feb; 34(2):145-52. PMID: 24222397.
      View in: PubMed
    19. Benn P, Borrell A, Chiu R, Cuckle H, Dugoff L, Faas B, Gross S, Johnson J, Maymon R, Norton M, Odibo A, Schielen P, Spencer K, Huang T, Wright D, Yaron Y. Response to "On gestational weeks and maths". Prenat Diagn. 2013 Dec; 33(12):1218-9. PMID: 24307534.
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    20. Benn PA. Prenatal technologies and the sex ratio. Genet Med. 2014 Jun; 16(6):433-4. PMID: 24177056.
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    21. Shamshirsaz AA, Ravangard SF, Turner G, Borgida A, Janicki MB, Campbell WA, Zelop C, Shamshirsaz AA, Spiel M, Prabulos AM, Feldman D, Rodis J, Ingardia CJ, Gurram P, Fuller K, Fang YM, Benn P, Egan JF. Efficacy of the genetic sonogram in a stepwise sequential protocol for down syndrome screening. J Ultrasound Med. 2013 Sep; 32(9):1607-13. PMID: 23980222.
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    22. Cuckle H, Benn P, Pergament E. Clinical utility and cost of non-invasive prenatal testing. J Matern Fetal Neonatal Med. 2014 Feb; 27(3):320-1. PMID: 23875873.
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    23. Shamshirsaz AA, Salmanian B, Ravangard SF, Shamshirsaz AA, Javadian P, Borgida A, Turner G, Feldman D, Spiel M, Benn P, Campbell WA. Nuchal translucency and cardiac abnormalities in euploid singleton pregnancies. J Matern Fetal Neonatal Med. 2014 Mar; 27(5):495-9. PMID: 23806115.
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    24. Benn P, Cuckle H, Pergament E. Non-invasive prenatal testing for aneuploidy: current status and future prospects. Ultrasound Obstet Gynecol. 2013 Jul; 42(1):15-33. PMID: 23765643.
      View in: PubMed
    25. Cuckle H, Benn P, Pergament E. Maternal cfDNA screening for Down syndrome--a cost sensitivity analysis. Prenat Diagn. 2013 Jul; 33(7):636-42. PMID: 23674341.
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    26. Gurram P, Benn P, Campbell WA. Impact of diabetes on aneuploidy screening. Clin Lab Med. 2013 Jun; 33(2):271-80. PMID: 23702117.
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    27. Benn P, Borell A, Chiu R, Cuckle H, Dugoff L, Faas B, Gross S, Johnson J, Maymon R, Norton M, Odibo A, Schielen P, Spencer K, Huang T, Wright D, Yaron Y. Position statement from the Aneuploidy Screening Committee on behalf of the Board of the International Society for Prenatal Diagnosis. Prenat Diagn. 2013 Jul; 33(7):622-9. PMID: 23616385.
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    28. Benn PA. Prenatal counseling and the detection of copy-number variants. Genet Med. 2013 Apr; 15(4):316-7. PMID: 23552451.
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    29. Norton ME, Rose NC, Benn P. Noninvasive prenatal testing for fetal aneuploidy: clinical assessment and a plea for restraint. Obstet Gynecol. 2013 Apr; 121(4):847-50. PMID: 23635685.
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    30. Chapman AR, Benn PA. Noninvasive prenatal testing for early sex identification: a few benefits and many concerns. Perspect Biol Med. 2013; 56(4):530-47. PMID: 24769746.
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    31. Faas BH, Odibo AO, Cirigliano V, Schielen P, Pergament D, Devers P, Oepkes D, Benn P. Summary of the ISPD Preconference Day, June 3, 2012, Miami Beach. Prenat Diagn. 2013 Jan; 33(1):1-5. PMID: 23132177.
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    32. Guanciali-Franchi P, Iezzi I, Soranno A, de Volo CP, Alfonsi M, Calabrese G, Benn P. Optimal cut-offs for Down syndrome contingent screening in a population of 10,156 pregnant women. Prenat Diagn. 2012 Dec; 32(12):1147-50. PMID: 23007955.
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    33. Benn P, Cuckle H, Pergament E. Genome-wide fetal aneuploidy detection by maternal plasma DNA sequencing. Obstet Gynecol. 2012 Jun; 119(6):1270; author reply 1270-1. PMID: 22617594.
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    34. Benn P, Cuckle H, Pergament E. Non-invasive prenatal diagnosis for Down syndrome: the paradigm will shift, but slowly. Ultrasound Obstet Gynecol. 2012 Feb; 39(2):127-30. PMID: 22278776.
      View in: PubMed
    35. Benn P, Borrell A, Cuckle H, Dugoff L, Gross S, Johnson JA, Maymon R, Odibo A, Schielen P, Spencer K, Wright D, Yaron Y. Prenatal Detection of Down Syndrome using Massively Parallel Sequencing (MPS): a rapid response statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, 24 October 2011. Prenat Diagn. 2012 Jan; 32(1):1-2. PMID: 22275335.
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    36. Guanciali-Franchi P, Iezzi I, Palka C, Matarrelli B, Morizio E, Calabrese G, Benn P. Comparison of combined, stepwise sequential, contingent, and integrated screening in 7292 high-risk pregnant women. Prenat Diagn. 2011 Nov; 31(11):1077-81. PMID: 21800336.
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    37. Benn P, Borrell A, Crossley J, Cuckle H, Dugoff L, Gross S, Johnson JA, Maymon R, Odibo A, Schielen P, Spencer K, Wright D, Yaron Y. Aneuploidy screening: a position statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, January 2011. Prenat Diagn. 2011 Jun; 31(6):519-22. PMID: 21604286.
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    38. Egan JF, Campbell WA, Chapman A, Shamshirsaz AA, Gurram P, Benn PA. Distortions of sex ratios at birth in the United States; evidence for prenatal gender selection. Prenat Diagn. 2011 Jun; 31(6):560-5. PMID: 21442626.
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    39. Kourelis TV, Kahl BS, Benn P, Delach JA, Bilgrami SF. Treatment of synchronous mantle cell lymphoma and small lymphocytic lymphoma with bendamustine and rituximab. Acta Haematol. 2011; 126(1):40-3. PMID: 21430370.
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    40. Egan JF, Smith K, Timms D, Bolnick JM, Campbell WA, Benn PA. Demographic differences in Down syndrome livebirths in the US from 1989 to 2006. Prenat Diagn. 2011 Apr; 31(4):389-94. PMID: 21302335.
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    41. Shamshirsaz AA, Benn P, Egan JF. The role of second-trimester serum screening in the post-first-trimester screening era. Clin Lab Med. 2010 Sep; 30(3):667-76. PMID: 20638580.
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    42. Benn PA, Chapman AR. Ethical challenges in providing noninvasive prenatal diagnosis. Curr Opin Obstet Gynecol. 2010 Apr; 22(2):128-34. PMID: 20098325.
      View in: PubMed
    43. Benn PA, Chapman AR. Practical and ethical considerations of noninvasive prenatal diagnosis. JAMA. 2009 May 27; 301(20):2154-6. PMID: 19470991.
      View in: PubMed
    44. Fang YM, Benn P, Campbell W, Bolnick J, Prabulos AM, Egan JF. Down syndrome screening in the United States in 2001 and 2007: a survey of maternal-fetal medicine specialists. Am J Obstet Gynecol. 2009 Jul; 201(1):97.e1-5. PMID: 19467637.
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    45. Fang YM, Benn P, Egan JF. Use of the genetic sonogram in the United States in 2001 and 2007. J Ultrasound Med. 2008 Nov; 27(11):1543-8. PMID: 18946092.
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    46. Benn P, Delach J. Human lymphocyte culture and chromosome analysis. CSH Protoc. 2008; 2008:pdb.prot5035. PMID: 21356908.
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    47. Benn PA, Egan JF. Expected performance of second trimester maternal serum testing followed by a 'genetic sonogram' in screening of fetal Down syndrome. Prenat Diagn. 2008 Mar; 28(3):230-5. PMID: 18264966.
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    48. Benn PA, Egan JF. Second trimester prenatal ultrasound and screening for Down syndrome. Prenat Diagn. 2007 Sep; 27(9):884. PMID: 17724762.
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    49. Benn PA, Campbell WA, Zelop CM, Ingardia C, Egan JF. Stepwise sequential screening for fetal aneuploidy. Am J Obstet Gynecol. 2007 Sep; 197(3):312.e1-5. PMID: 17826434.
      View in: PubMed
    50. Gorusu M, Benn P, Li Z, Fang M. On the genesis and prognosis of variant translocations in chronic myeloid leukemia. Cancer Genet Cytogenet. 2007 Mar; 173(2):97-106. PMID: 17321324.
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    51. Gianferrari EA, Benn PA, Dries L, Brault K, Egan JF, Zelop CM. Absent or shortened nasal bone length and the detection of Down Syndrome in second-trimester fetuses. Obstet Gynecol. 2007 Feb; 109(2 Pt 1):371-5. PMID: 17267838.
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    52. Wright D, Bradbury I, Benn P, Nix B, Spencer K, Cuckle H. CT ratios: parameter estimates are inconsistent with SURUSS publications? Prenat Diagn. 2006 Oct; 26(10):991-2; author reply 994. PMID: 17029298.
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    53. Benn PA, Makowski GS, Egan JF, Wright D. Reproducibility of risk figures in 2nd-trimester maternal serum screening for down syndrome: comparison of 2 laboratories. Clin Chem. 2006 Nov; 52(11):2087-94. PMID: 16990427.
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    54. Wright D, Bradbury I, Cuckle H, Gardosi J, Tonks A, Standing S, Benn P. Three-stage contingent screening for Down syndrome. Prenat Diagn. 2006 Jun; 26(6):528-34. PMID: 16634118.
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    55. Benn P, Donnenfeld AE. Sequential Down syndrome screening: the importance of first and second trimester test correlations when calculating risk. J Genet Couns. 2005 Dec; 14(6):409-13. PMID: 16388325.
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    56. Zelop CM, Milewski E, Brault K, Benn P, Borgida AF, Egan JF. Variation of fetal nasal bone length in second-trimester fetuses according to race and ethnicity. J Ultrasound Med. 2005 Nov; 24(11):1487-9. PMID: 16239650.
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    57. Ronski K, Sanders M, Burleson JA, Moyo V, Benn P, Fang M. Early growth response gene 1 (EGR1) is deleted in estrogen receptor-negative human breast carcinoma. Cancer. 2005 Sep 1; 104(5):925-30. PMID: 15999367.
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    58. Cuckle H, Benn P, Wright D. Down syndrome screening in the first and/or second trimester: model predicted performance using meta-analysis parameters. Semin Perinatol. 2005 Aug; 29(4):252-7. PMID: 16104677.
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    59. Benn P, Wright D, Cuckle H. Practical strategies in contingent sequential screening for Down syndrome. Prenat Diagn. 2005 Aug; 25(8):645-52. PMID: 16049988.
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    60. Wright D, Bradbury I, Benn P, Cuckle H, Ritchie K. Which contingent sequential screening protocol? Prenat Diagn. 2005 Jun; 25(6):520-1. PMID: 15966050.
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    61. Benn PA, Fang M, Egan JF. Trends in the use of second trimester maternal serum screening from 1991 to 2003. Genet Med. 2005 May-Jun; 7(5):328-31. PMID: 15915084.
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    62. Wright D, Bradbury I, Benn P, Cuckle H, Ritchie K. Contingent screening for Down syndrome is an efficient alternative to non-disclosure sequential screening. Prenat Diagn. 2004 Oct; 24(10):762-6. PMID: 15503281.
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    63. Egan JF, Benn PA, Zelop CM, Bolnick A, Gianferrari E, Borgida AF. Down syndrome births in the United States from 1989 to 2001. Am J Obstet Gynecol. 2004 Sep; 191(3):1044-8. PMID: 15467587.
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    64. Benn PA, Egan JF, Fang M, Smith-Bindman R. Changes in the utilization of prenatal diagnosis. Obstet Gynecol. 2004 Jun; 103(6):1255-60. PMID: 15172861.
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    65. Souter VL, Nyberg DA, Benn PA, Zebelman A, Luthardt F, Luthy DA. Correlation of second-trimester sonographic and biochemical markers. J Ultrasound Med. 2004 Apr; 23(4):505-11. PMID: 15098869.
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    66. Benn PA, Ying J. Preliminary estimate for the second-trimester maternal serum screening detection rate of the 45,X karyotype using alpha-fetoprotein, unconjugated estriol and human chorionic gonadotropin. J Matern Fetal Neonatal Med. 2004 Mar; 15(3):160-6. PMID: 15280141.
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    67. Pinette MG, Egan JF, Wax JR, Blackstone J, Cartin A, Benn PA. Combined sonographic and biochemical markers for Down syndrome screening. J Ultrasound Med. 2003 Nov; 22(11):1185-90. PMID: 14620889.
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    68. Benn P. S100beta protein and amniotic fluid. Clin Chim Acta. 2003 Sep; 335(1-2):169. PMID: 12927700.
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    69. Benn P. Improved antenatal screening for Down's syndrome. Lancet. 2003 Mar 8; 361(9360):794-5. PMID: 12642040.
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    70. Benn PA, Fang M, Egan JF, Horne D, Collins R. Incorporation of inhibin-A in second-trimester screening for Down syndrome. Obstet Gynecol. 2003 Mar; 101(3):451-4. PMID: 12636947.
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    71. Hartnett J, Borgida AF, Benn PA, Feldman DM, DeRoche ME, Egan JF. Cost analysis of Down syndrome screening in advanced maternal age. J Matern Fetal Neonatal Med. 2003 Feb; 13(2):80-4. PMID: 12735407.
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    72. Benn PA, Kaminsky LM, Ying J, Borgida AF, Egan JF. Combined second-trimester biochemical and ultrasound screening for Down syndrome. Obstet Gynecol. 2002 Dec; 100(6):1168-76. PMID: 12468159.
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    73. Egan JF, Kaminsky LM, DeRoche ME, Barsoom MJ, Borgida AF, Benn PA. Antenatal Down syndrome screening in the United States in 2001: a survey of maternal-fetal medicine specialists. Am J Obstet Gynecol. 2002 Nov; 187(5):1230-4. PMID: 12439510.
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    74. Abbott MA, Benn P. Prenatal genetic diagnosis of Down's syndrome. Expert Rev Mol Diagn. 2002 Nov; 2(6):605-15. PMID: 12465456.
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    75. Benn PA. Advances in prenatal screening for Down syndrome: II first trimester testing, integrated testing, and future directions. Clin Chim Acta. 2002 Oct; 324(1-2):1-11. PMID: 12204419.
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    76. Benn PA. Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing. Clin Chim Acta. 2002 Sep; 323(1-2):1-16. PMID: 12135803.
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    77. Benn PA, Egan JF, Ingardia CJ. Extreme second-trimester serum analyte values in down syndrome pregnancies with hydrops fetalis. J Matern Fetal Neonatal Med. 2002 Apr; 11(4):262-5. PMID: 12375682.
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    78. Egan JF, Malakh L, Turner GW, Markenson G, Wax JR, Benn PA. Role of ultrasound for Down syndrome screening in advanced maternal age. Am J Obstet Gynecol. 2001 Nov; 185(5):1028-31. PMID: 11717626.
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    79. Benn PA. Singleton versus duplicate assays in maternal serum screening. Prenat Diagn. 2001 Oct; 21(10):894-6. PMID: 11746137.
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    80. Benn PA, Gainey A, Ingardia CJ, Rodis JF, Egan JF. Second trimester maternal serum analytes in triploid pregnancies: correlation with phenotype and sex chromosome complement. Prenat Diagn. 2001 Aug; 21(8):680-6. PMID: 11536271.
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    81. Egan JF, Rodis JF, Benn PA. Ultrasound markers of fetal Down syndrome. JAMA. 2001 Jun 13; 285(22):2856-7; author reply 2858. PMID: 11401603.
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    82. Benn PA, Collins R. Evaluation of effect of analytical imprecision in maternal serum screening for Down's syndrome. Ann Clin Biochem. 2001 Jan; 38(Pt 1):28-36. PMID: 11270838.
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    83. Benn PA, Ying J, Beazoglou T, Egan JF. Estimates for the sensitivity and false-positive rates for second trimester serum screening for Down syndrome and trisomy 18 with adjustment for cross-identification and double-positive results. Prenat Diagn. 2001 Jan; 21(1):46-51. PMID: 11180240.
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    84. Egan JF, Benn P, Borgida AF, Rodis JF, Campbell WA, Vintzileos AM. Efficacy of screening for fetal Down syndrome in the United States from 1974 to 1997. Obstet Gynecol. 2000 Dec; 96(6):979-85. PMID: 11084189.
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    85. Wax JR, Lopes AM, Benn PA, Lerer T, Steinfeld JD, Ingardia CJ. Unexplained elevated midtrimester maternal serum levels of alpha fetoprotein, human chorionic gonadotropin, or low unconjugated estriol: recurrence risk and association with adverse perinatal outcome. J Matern Fetal Med. 2000 May-Jun; 9(3):161-4. PMID: 10914623.
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    86. Benn PA, Craffey A, Horne D, Ramsdell L, Rodis JF. Elevated maternal serum alpha-fetoprotein with low unconjugated estriol and the risk for lethal perinatal outcome. J Matern Fetal Med. 2000 May-Jun; 9(3):165-9. PMID: 10914624.
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    87. Benn PA, Egan JF. Survival of Down syndrome in utero. Prenat Diagn. 2000 May; 20(5):432-3. PMID: 10820415.
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    88. Wax JR, Benn P, Steinfeld JD, Ingardia CJ. Prenatally diagnosed sacrococcygeal teratoma: a unique expression of trisomy 1q. Cancer Genet Cytogenet. 2000 Feb; 117(1):84-6. PMID: 10700874.
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    89. Wallerstein R, Yu MT, Neu RL, Benn P, Lee Bowen C, Crandall B, Disteche C, Donahue R, Harrison B, Hershey D, Higgins RR, Jenkins LS, Jackson-Cook C, Keitges E, Khodr G, Lin CC, Luthardt FW, Meisner L, Mengden G, Patil SR, Rodriguez M, Sciorra LJ, Shaffer LG, Stetten G, Van Dyke DL, Wang H. Common trisomy mosaicism diagnosed in amniocytes involving chromosomes 13, 18, 20 and 21: karyotype-phenotype correlations. Prenat Diagn. 2000 Feb; 20(2):103-22. PMID: 10694683.
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    90. Hsu LY, Benn PA. Revised guidelines for the diagnosis of mosaicism in amniocytes. Prenat Diagn. 1999 Nov; 19(11):1081-82. PMID: 10589067.
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    91. Pilarski RT, Brothman AR, Benn P, Shulman Rosengren S. Attenuated familial adenomatous polyposis in a man with an interstitial deletion of chromosome arm 5q. Am J Med Genet. 1999 Oct 8; 86(4):321-4. PMID: 10494086.
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    92. Tanski S, Rosengren SS, Benn PA. Predictive value of the triple screening test for the phenotype of Down syndrome. Am J Med Genet. 1999 Jul 16; 85(2):123-6. PMID: 10406664.
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    93. Benn PA, Rodis JF, Beazoglou T. Cost-effectiveness of estimating gestational age by ultrasonography in Down syndrome screening. Obstet Gynecol. 1999 Jul; 94(1):29-33. PMID: 10389713.
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    94. Benn PA, Leo MV, Rodis JF, Beazoglou T, Collins R, Horne D. Maternal serum screening for fetal trisomy 18: a comparison of fixed cutoff and patient-specific risk protocols. Obstet Gynecol. 1999 May; 93(5 Pt 1):707-11. PMID: 10912972.
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    95. Devi A, Benn PA. X-chromosome abnormalities in women with premature ovarian failure. J Reprod Med. 1999 Apr; 44(4):321-4. PMID: 10319299.
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    96. Beazoglou T, Heffley D, Kyriopoulos J, Vintzileos A, Benn P. Economic evaluation of prenatal screening for Down syndrome in the U.S.A. Prenat Diagn. 1998 Dec; 18(12):1241-52. PMID: 9885015.
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    97. Benn P. Trisomy 16 and trisomy 16 Mosaicism: a review. Am J Med Genet. 1998 Sep 1; 79(2):121-33. PMID: 9741470.
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    98. Devi AS, Metzger DA, Luciano AA, Benn PA. 45,X/46,XX mosaicism in patients with idiopathic premature ovarian failure. Fertil Steril. 1998 Jul; 70(1):89-93. PMID: 9660427.
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    99. Benn PA. Preliminary evidence for associations between second-trimester human chorionic gonadotropin and unconjugated oestriol levels with pregnancy outcome in Down syndrome pregnancies. Prenat Diagn. 1998 Apr; 18(4):319-24. PMID: 9602476.
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    100. Benn P. Aging chromosome telomeres: parallel studies with terminal repeat and telomere associated DNA probes. Mech Ageing Dev. 1997 Dec 15; 99(2):153-66. PMID: 9483489.
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    101. Benn PA, Borgida A, Horne D, Briganti S, Collins R, Rodis JF. Down syndrome and neural tube defect screening: the value of using gestational age by ultrasonography. Am J Obstet Gynecol. 1997 May; 176(5):1056-61. PMID: 9166168.
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    102. Hsu LY, Yu MT, Neu RL, Van Dyke DL, Benn PA, Bradshaw CL, Shaffer LG, Higgins RR, Khodr GS, Morton CC, Wang H, Brothman AR, Chadwick D, Disteche CM, Jenkins LS, Kalousek DK, Pantzar TJ, Wyatt P. Rare trisomy mosaicism diagnosed in amniocytes, involving an autosome other than chromosomes 13, 18, 20, and 21: karyotype/phenotype correlations. Prenat Diagn. 1997 Mar; 17(3):201-42. PMID: 9110367.
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    103. Greger V, Knoll JH, Wagstaff J, Woolf E, Lieske P, Glatt H, Benn PA, Rosengren SS, Lalande M. Angelman syndrome associated with an inversion of chromosome 15q11.2q24.3. Am J Hum Genet. 1997 Mar; 60(3):574-80. PMID: 9042916; PMCID: PMC1712510.
    104. Benn PA. Down syndrome and open neural tube defect screen-positive pregnancies: premature delivery and premature placental karyotyping. Prenat Diagn. 1997 Mar; 17(3):282-4. PMID: 9110375.
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    105. Cassidy SB, Forsythe M, Heeger S, Nicholls RD, Schork N, Benn P, Schwartz S. Comparison of phenotype between patients with Prader-Willi syndrome due to deletion 15q and uniparental disomy 15. Am J Med Genet. 1997 Feb 11; 68(4):433-40. PMID: 9021017.
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    106. Benn PA, Clive JM, Collins R. Medians for second-trimester maternal serum alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol; differences between races or ethnic groups. Clin Chem. 1997 Feb; 43(2):333-7. PMID: 9023136.
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    107. Tantravahi U, Matsumoto C, Delach J, Craffey A, Smeltzer J, Benn P. Trisomy 16 mosaicism in amniotic fluid cell cultures. Prenat Diagn. 1996 Aug; 16(8):749-54. PMID: 8878286.
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    108. Benn PA, Horne D, Craffey A, Collins R, Ramsdell L, Greenstein R. Maternal serum screening for birth defects: results of a Connecticut regional program. Conn Med. 1996 Jun; 60(6):323-7. PMID: 8706425.
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    109. Benn PA, Horne D, Briganti S, Rodis JF, Clive JM. Elevated second-trimester maternal serum hCG alone or in combination with elevated alpha-fetoprotein. Obstet Gynecol. 1996 Feb; 87(2):217-22. PMID: 8559527.
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    110. Cusick W, Bork M, Fabri B, Benn P, Rodis JF, Buttino L. Trisomy 16 fetus surviving into the second trimester. Prenat Diagn. 1995 Nov; 15(11):1078-81. PMID: 8606889.
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    111. Pilarski RT, Greenstein RM, Benn P. Developing a role for genetics within a cancer program. Ann N Y Acad Sci. 1995 Sep 30; 768:258-60. PMID: 8526361.
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    112. Benn PA, Horne D, Briganti S, Greenstein RM. Prenatal diagnosis of diverse chromosome abnormalities in a population of patients identified by triple-marker testing as screen positive for Down syndrome. Am J Obstet Gynecol. 1995 Aug; 173(2):496-501. PMID: 7544068.
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    113. Delach JA, Rosengren SS, Kaplan L, Greenstein RM, Cassidy SB, Benn PA. Comparison of high resolution chromosome banding and fluorescence in situ hybridization (FISH) for the laboratory evaluation of Prader-Willi syndrome and Angelman syndrome. Am J Med Genet. 1994 Aug 1; 52(1):85-91. PMID: 7977469.
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    114. Devi AS, Velinov M, Kamath MV, Eisenfeld L, Neu R, Ciarleglio L, Greenstein R, Benn P. Variable clinical expression of mosaic trisomy 16 in the newborn infant. Am J Med Genet. 1993 Aug 15; 47(2):294-8. PMID: 8213923.
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    115. Lu G, Altman AJ, Benn PA. Review of the cytogenetic changes in acute megakaryoblastic leukemia: one disease or several? Cancer Genet Cytogenet. 1993 Jun; 67(2):81-9. PMID: 8330276.
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    116. Chen LL, Narayanan R, Hibbs MS, Benn PA, Clawson ML, Lu G, Rhim JS, Greenberg B, Mendelsohn J. Altered epidermal growth factor signal transduction in activated Ha-ras-transformed human keratinocytes. Biochem Biophys Res Commun. 1993 May 28; 193(1):167-74. PMID: 8503904.
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    117. Pertschuk LP, Feldman JG, Kim DS, Nayeri K, Eisenberg KB, Carter AC, Thelmo WT, Rhong ZT, Benn P, Grossman A. Steroid hormone receptor immunohistochemistry and amplification of c-myc protooncogene. Relationship to disease-free survival in breast cancer. Cancer. 1993 Jan 1; 71(1):162-71. PMID: 8416713.
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    118. Hsu LY, Kaffe S, Jenkins EC, Alonso L, Benn PA, David K, Hirschhorn K, Lieber E, Shanske A, Shapiro LR, et al. Proposed guidelines for diagnosis of chromosome mosaicism in amniocytes based on data derived from chromosome mosaicism and pseudomosaicism studies. Prenat Diagn. 1992 Jul; 12(7):555-73. PMID: 1508847.
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    119. Benn P, Ciarleglio L, Lettieri L, Rodis J, Greenstein R. A rapid (but wrong) prenatal diagnosis. N Engl J Med. 1992 Jun 11; 326(24):1638-40. PMID: 1584278.
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    120. Wang JC, Lang HD, Lichter S, Weinstein M, Benn P. Cytogenetic studies of bone marrow fibroblasts cultured from patients with myelofibrosis and myeloid metaplasia. Br J Haematol. 1992 Feb; 80(2):184-8. PMID: 1550774.
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    121. Mills KI, Benn P, Birnie GD. Does the breakpoint within the major breakpoint cluster region (M-bcr) influence the duration of the chronic phase in chronic myeloid leukemia? An analytical comparison of current literature. Blood. 1991 Sep 1; 78(5):1155-61. PMID: 1878582.
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    122. Grossman A, Silver RT, Szatroswki TP, Gutfriend A, Verma RS, Benn PA. Densitometric analysis of Southern blot autoradiographs and its application to monitoring patients with chronic myeloid leukemia. Leukemia. 1991 Jul; 5(7):540-7. PMID: 2072739.
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    123. Benn P, Birnie GD, MacKenzie E, Mills KI. bcr breakpoint and prognosis of chronic phase chronic myeloid leukemia. Blood. 1990 Dec 15; 76(12):2637-9. PMID: 2265256.
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    124. Weinstein M, Grossman A, Dittmar K, Weiss R, Benn P. Highly complex genetic rearrangement involving at least seven breakpoints in a case of chronic myeloid leukemia. Cancer Genet Cytogenet. 1990 Aug 1; 48(1):75-81. PMID: 2164879.
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    125. Silver RT, Benn P, Verma RS, Coleman M, Soper L, Gutfriend A. Recombinant gamma-interferon has activity in chronic myeloid leukemia. Am J Clin Oncol. 1990 Feb; 13(1):49-54. PMID: 2154924.
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    126. Grossman A, Mathew A, O'Connell MP, Tiso P, Distenfeld A, Benn P. Multiple restriction enzyme digests are required to rule out polymorphism in the molecular diagnosis of chronic myeloid leukemia. Leukemia. 1990 Jan; 4(1):63-4. PMID: 1967323.
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    127. Grossman A, Silver RT, Arlin Z, Coleman M, Camposano E, Gascon P, Benn PA. Fine mapping of chromosome 22 breakpoints within the breakpoint cluster region (bcr) implies a role for bcr exon 3 in determining disease duration in chronic myeloid leukemia. Am J Hum Genet. 1989 Nov; 45(5):729-38. PMID: 2683759; PMCID: PMC1683428.
    128. Dubé I, Dixon J, Beckett T, Grossman A, Weinstein M, Benn P, McKeithan T, Norman C, Pinkerton P. Location of breakpoints within the major breakpoint cluster region (bcr) in 33 patients with bcr rearrangement-positive chronic myeloid leukemia (CML) with complex or absent Philadelphia chromosomes. Genes Chromosomes Cancer. 1989 Sep; 1(1):106-11. PMID: 2487142.
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    129. Verma RS, Macera MJ, Benn P, Groffen J. Molecular characterization of variant translocations in chronic myelogenous leukemia. Oncogene. 1989 Sep; 4(9):1145-8. PMID: 2674857.
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    130. Birnie GD, Mills KI, Benn P. Does the site of the breakpoint on chromosome 22 influence the duration of the chronic phase in chronic myeloid leukemia? Leukemia. 1989 Aug; 3(8):545-7. PMID: 2747287.
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    131. Benn P, Grossman A, Soper L, Halka K, Eisenberg A, Gascon P. A rare restriction enzyme site polymorphism in the breakpoint cluster region (bcr) of chromosome 22. Leukemia. 1988 Nov; 2(11):760-2. PMID: 2903273.
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    132. Botti AC, Silver RT, Macera MJ, Benn P, Verma RS. A new translocation involving chromosomes 8 and 9 in a Philadelphia-negative chronic myelogenous leukemia. Cancer Genet Cytogenet. 1988 Oct 1; 35(1):51-4. PMID: 3180010.
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    133. Eisenberg A, Silver R, Soper L, Arlin Z, Coleman M, Bernhardt B, Benn P. The location of breakpoints within the breakpoint cluster region (bcr) of chromosome 22 in chronic myeloid leukemia. Leukemia. 1988 Oct; 2(10):642-7. PMID: 3172841.
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    134. Kaffe S, Benn PA, Hsu LY. Fetal blood sampling in investigation of chromosome mosaicism in amniotic fluid cell culture. Lancet. 1988 Jul 30; 2(8605):284. PMID: 2899277.
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    135. Benn P, Soper L, Eisenberg A, Silver RT, Coleman M, Cacciapaglia B, Bennett L, Baird M, Silverstein M, Berger C, et al. Utility of molecular genetic analysis of bcr rearrangement in the diagnosis of chronic myeloid leukemia. Cancer Genet Cytogenet. 1987 Nov; 29(1):1-7. PMID: 2822224.
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    136. Benn PA, Hsu LY, Verma RS, Alonso ML, Reich E, Wishnick M. Prenatal diagnosis of minute 5p- deletion: a cytogenetic problem in detection. Obstet Gynecol. 1987 Sep; 70(3 Pt 2):449-52. PMID: 3627600.
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    137. Hsu LY, Benn PA, Tannenbaum HL, Perlis TE, Carlson AD. Chromosomal polymorphisms of 1, 9, 16, and Y in 4 major ethnic groups: a large prenatal study. Am J Med Genet. 1987 Jan; 26(1):95-101. PMID: 3812584.
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    138. Benn PA, Hsu LY. Evidence for preferential involvement of chromosome bands 6p21 and 13q14 in amniotic fluid cell balanced translocation pseudomosaicism. Clin Genet. 1986 Feb; 29(2):116-21. PMID: 3955861.
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    139. Benn PA, Hsu LY, Carlson A, Tannenbaum HL. The centralized prenatal genetics screening program of New York City III: The first 7,000 cases. Am J Med Genet. 1985 Feb; 20(2):369-84. PMID: 2579556.
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    140. Shapiro LR, Pettersen RO, Wilmot PL, Warburton D, Benn PA, Hsu LY. Pericentric inversion of the Y chromosome and prenatal diagnosis. Prenat Diagn. 1984 Nov-Dec; 4(6):463-5. PMID: 6522349.
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    141. Benn PA, Hsu LY. Incidence and significance of supernumerary marker chromosomes in prenatal diagnosis. Am J Hum Genet. 1984 Sep; 36(5):1092-102. PMID: 6594043; PMCID: PMC1684529.
    142. Benn PA, Gilbert F, Hsu LY. Maternal cell contamination of amniotic fluid cell cultures from two consecutive pregnancies complicated by fibroids. Prenat Diagn. 1984 Mar-Apr; 4(2):151-3. PMID: 6739438.
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    143. Benn P, Hsu LY, Perlis T, Schonhaut A. Prenatal diagnosis of chromosome mosaicism. Prenat Diagn. 1984 Jan-Feb; 4(1):1-9. PMID: 6728823.
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    144. Benn PA, Hsu LY. Maternal cell contamination of amniotic fluid cell cultures: results of a U.S. nationwide survey. Am J Med Genet. 1983 Jun; 15(2):297-305. PMID: 6349361.
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    145. Benn PA, Schonhaut AG, Hsu LY. A high incidence of maternal cell contamination of amniotic fluid cell cultures. Am J Med Genet. 1983 Feb; 14(2):361-5. PMID: 6837631.
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    146. Benn PA, Sugarman M, Greco MA, Harris G, Deguire GB, Hsu LY. Prenatal diagnosis of 49, XXXYY. Prenat Diagn. 1982 Oct; 2(4):309-12. PMID: 7156028.
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    147. Hsu LY, Benn PA. The centralized prenatal genetics screening program of New York City: II. Establishment of prenatal diagnosis laboratory. Am J Med Genet. 1981; 8(3):331-9. PMID: 7234903.
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    148. Harnden DG, Benn PA, Oxford JM, Taylor AM, Webb TP. Cytogenetically marked clones in human fibroblasts cultured from normal subjects. Somatic Cell Genet. 1976 Jan; 2(1):55-62. PMID: 1028160.
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