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Last Name
Institution

Jeffrey C Hoch PhD

TitleProfessor
InstitutionUConn Health Center
DepartmentMolecular, Microbial and Structural Biology
AddressMC 3305
MC 3305
263 Farmington Avenue
Phone860-679-3566
Fax860-679-3408
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    Other Positions
    TitleDirector
    InstitutionUConn Health Center
    DepartmentGregory P. Mullen NMR Structural Biology Facility


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mobli M, Maciejewski MW, Schuyler AD, Stern AS, Hoch JC. Correction: Sparse sampling methods in multidimensional NMR. Phys Chem Chem Phys. 2016 Jul 28; 18(28):19482. PMID: 27364917.
      View in: PubMed
    2. Stern AS, Hoch JC. A new approach to compressed sensing for NMR. Magn Reson Chem. 2015 Nov; 53(11):908-12. PMID: 26256110.
      View in: PubMed
    3. Fenwick M, Hoch JC, Ulrich E, Gryk MR. CONNJUR R: an annotation strategy for fostering reproducibility in bio-NMR-protein spectral assignment. J Biomol NMR. 2015 Oct; 63(2):141-50. PMID: 26253947.
      View in: PubMed
    4. Palmer MR, Suiter CL, Henry GE, Rovnyak J, Hoch JC, Polenova T, Rovnyak D. Sensitivity of nonuniform sampling NMR. J Phys Chem B. 2015 Jun 4; 119(22):6502-15. PMID: 25901905.
      View in: PubMed
    5. Light D, Griffin M, Srivastava K, Danelli P, Ballerini A, Leone N, Bondurri A, Khare R, Shabbir A, Wijerathne S, So JB, Clara E, Tang SW, Tan WB, Hu J, Lomanto D, Ji Z, Li J, East B, Pazdirek F, Hoch J, Ji ZL, Malik D, Reddy P, Sahu D, Forgione U, Gianatiempo M, Xiong M, Chen B, Zhang JW, Li T, Luo XG, Li Q, Yu X, Zhao XD, Chen HY, Sun FX, Feng GZ, Zhang JP, Yu CZ, Aboulwafa A, Mahfouz A, Khairat M, Althani H, Albosoum E, Alebrahim H. Rare & Special Cases. Hernia. 2015 Apr; 19 Suppl 1:S19-24. PMID: 26518798.
      View in: PubMed
    6. Schuyler AD, Maciejewski MW, Stern AS, Hoch JC. Nonuniform sampling of hypercomplex multidimensional NMR experiments: Dimensionality, quadrature phase and randomization. J Magn Reson. 2015 May; 254:121-30. PMID: 25899289; PMCID: PMC4420639 [Available on 05/01/16].
    7. Mobli M, Hoch JC. Nonuniform sampling and non-Fourier signal processing methods in multidimensional NMR. Prog Nucl Magn Reson Spectrosc. 2014 Nov; 83:21-41. PMID: 25456315.
      View in: PubMed
    8. Suiter CL, Paramasivam S, Hou G, Sun S, Rice D, Hoch JC, Rovnyak D, Polenova T. Sensitivity gains, linearity, and spectral reproducibility in nonuniformly sampled multidimensional MAS NMR spectra of high dynamic range. J Biomol NMR. 2014 Jun; 59(2):57-73. PMID: 24752819; PMCID: PMC4142058.
    9. Hoch JC, Billeter M. The indelible mark of computation on bio-NMR. J Biomol NMR. 2014 Apr; 58(4):231-2. PMID: 24691942.
      View in: PubMed
    10. Hoch JC, Maciejewski MW, Mobli M, Schuyler AD, Stern AS. Nonuniform sampling and maximum entropy reconstruction in multidimensional NMR. Acc Chem Res. 2014 Feb 18; 47(2):708-17. PMID: 24400700; PMCID: PMC3982308.
    11. Schuyler AD, Maciejewski MW, Stern AS, Hoch JC. Formalism for hypercomplex multidimensional NMR employing partial-component subsampling. J Magn Reson. 2013 Feb; 227:20-4. PMID: 23246651; PMCID: PMC3552023.
    12. Sun S, Yan S, Guo C, Li M, Hoch JC, Williams JC, Polenova T. A time-saving strategy for MAS NMR spectroscopy by combining nonuniform sampling and paramagnetic relaxation assisted condensed data collection. J Phys Chem B. 2012 Nov 26; 116(46):13585-96. PMID: 23094591; PMCID: PMC3508383.
    13. Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, Cross TA, Dames S, Kessler H, Lange O, Madl T, Reif B, Sattler M, Eliezer D, Fersht A, Forman-Kay J, Kay LE, Fraser J, Gross J, Kortemme T, Sali A, Fujiwara T, Gardner K, Luo X, Rizo-Rey J, Rosen M, Gil RR, Ho C, Rule G, Gronenborn AM, Ishima R, Klein-Seetharaman J, Tang P, van der Wel P, Xu Y, Grzesiek S, Hiller S, Seelig J, Laue ED, Mott H, Nietlispach D, Barsukov I, Lian LY, Middleton D, Blumenschein T, Moore G, Campbell I, Schnell J, Vakonakis IJ, Watts A, Conte MR, Mason J, Pfuhl M, Sanderson MR, Craven J, Williamson M, Dominguez C, Roberts G, Günther U, Overduin M, Werner J, Williamson P, Blindauer C, Crump M, Driscoll P, Frenkiel T, Golovanov A, Matthews S, Parkinson J, Uhrin D, Williams M, Neuhaus D, Oschkinat H, Ramos A, Shaw DE, Steinbeck C, Vendruscolo M, Vuister GW, Walters KJ, Weinstein H, Wüthrich K, Yokoyama S. In support of the BMRB. Nat Struct Mol Biol. 2012 Sep; 19(9):854-60. PMID: 22955930.
      View in: PubMed
    14. Paramasivam S, Suiter CL, Hou G, Sun S, Palmer M, Hoch JC, Rovnyak D, Polenova T. Enhanced sensitivity by nonuniform sampling enables multidimensional MAS NMR spectroscopy of protein assemblies. J Phys Chem B. 2012 Jun 28; 116(25):7416-27. PMID: 22667827; PMCID: PMC3386641.
    15. Mobli M, Maciejewski MW, Schuyler AD, Stern AS, Hoch JC. Sparse sampling methods in multidimensional NMR. Phys Chem Chem Phys. 2012 Aug 21; 14(31):10835-43. PMID: 22481242; PMCID: PMC4229953.
    16. Bezsonova I, Rujan I, Bobenchik AM, Gorbatyuk V, Maciejewski MW, Gorbatyuk O, Hao B, Arthanari H, Mamoun CB, Hoch JC. (1)H, (13)C, and (15)N chemical shift assignments for PfPMT, a phosphoethanolamine methyltransferase from Plasmodium falciparum. Biomol NMR Assign. 2013 Apr; 7(1):17-20. PMID: 22392340; PMCID: PMC3882757.
    17. Gorbatyuk VY, Schiller MR, Gorbatyuk OI, Barwinski M, Hoch JC. N-terminal Dbl domain of the RhoGEF, Kalirin. J Biomol NMR. 2012 Mar; 52(3):269-76. PMID: 22314704; PMCID: PMC3362688.
    18. Maciejewski MW, Mobli M, Schuyler AD, Stern AS, Hoch JC. Data sampling in multidimensional NMR: fundamentals and strategies. Top Curr Chem. 2012; 316:49-77. PMID: 21773916.
      View in: PubMed
    19. Maciejewski MW, Fenwick M, Schuyler AD, Stern AS, Gorbatyuk V, Hoch JC. Random phase detection in multidimensional NMR. Proc Natl Acad Sci U S A. 2011 Oct 4; 108(40):16640-4. PMID: 21949370; PMCID: PMC3189084.
    20. Schuyler AD, Maciejewski MW, Arthanari H, Hoch JC. Knowledge-based nonuniform sampling in multidimensional NMR. J Biomol NMR. 2011 Jul; 50(3):247-62. PMID: 21626215; PMCID: PMC3199958.
    21. Bobenchik AM, Augagneur Y, Hao B, Hoch JC, Ben Mamoun C. Phosphoethanolamine methyltransferases in phosphocholine biosynthesis: functions and potential for antiparasite therapy. FEMS Microbiol Rev. 2011 Jul; 35(4):609-19. PMID: 21303393; PMCID: PMC4107886.
    22. Mobli M, Stern AS, Bermel W, King GF, Hoch JC. A non-uniformly sampled 4D HCC(CO)NH-TOCSY experiment processed using maximum entropy for rapid protein sidechain assignment. J Magn Reson. 2010 May; 204(1):160-4. PMID: 20299257; PMCID: PMC2859963.
    23. Hoch JC. New NMR machines are set to boost biomedical potential. Nature. 2010 Feb 25; 463(7284):1018. PMID: 20182489.
      View in: PubMed
    24. Bobenchik AM, Choi JY, Mishra A, Rujan IN, Hao B, Voelker DR, Hoch JC, Mamoun CB. Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay. BMC Biochem. 2010; 11:4. PMID: 20085640; PMCID: PMC2824672.
    25. Maciejewski MW, Qui HZ, Rujan I, Mobli M, Hoch JC. Nonuniform sampling and spectral aliasing. J Magn Reson. 2009 Jul; 199(1):88-93. PMID: 19414274; PMCID: PMC3108246.
    26. Hoch JC, Maciejewski MW, Gryk MR. Comment on "magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain". Science. 2008 Aug 1; 321(5889):640. PMID: 18669844; PMCID: PMC3049173.
    27. Hoch JC, Maciejewski MW, Filipovic B. Randomization improves sparse sampling in multidimensional NMR. J Magn Reson. 2008 Aug; 193(2):317-20. PMID: 18547850; PMCID: PMC2574885.
    28. Gryk MR, Hoch JC. Local knowledge helps determine protein structures. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4533-4. PMID: 18353980; PMCID: PMC2290792.
    29. Reynolds JM, Takebe S, Choi JY, El Bissati K, Witola WH, Bobenchik AM, Hoch JC, Voelker DR, Mamoun CB. Biochemical and genetic analysis of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum. J Biol Chem. 2008 Mar 21; 283(12):7894-900. PMID: 18178564.
      View in: PubMed
    30. Mobli M, Maciejewski MW, Gryk MR, Hoch JC. Automatic maximum entropy spectral reconstruction in NMR. J Biomol NMR. 2007 Oct; 39(2):133-9. PMID: 17701276.
      View in: PubMed
    31. Stern AS, Donoho DL, Hoch JC. NMR data processing using iterative thresholding and minimum l(1)-norm reconstruction. J Magn Reson. 2007 Oct; 188(2):295-300. PMID: 17723313; PMCID: PMC3199954.
    32. Mobli M, Maciejewski MW, Gryk MR, Hoch JC. An automated tool for maximum entropy reconstruction of biomolecular NMR spectra. Nat Methods. 2007 Jun; 4(6):467-8. PMID: 17538627.
      View in: PubMed
    33. Jordan JB, Kovacs H, Wang Y, Mobli M, Luo R, Anklin C, Hoch JC, Kriwacki RW. Three-dimensional 13C-detected CH3-TOCSY using selectively protonated proteins: facile methyl resonance assignment and protein structure determination. J Am Chem Soc. 2006 Jul 19; 128(28):9119-28. PMID: 16834385.
      View in: PubMed
    34. Mobli M, Stern AS, Hoch JC. Spectral reconstruction methods in fast NMR: reduced dimensionality, random sampling and maximum entropy. J Magn Reson. 2006 Sep; 182(1):96-105. PMID: 16815055.
      View in: PubMed
    35. Frueh DP, Sun ZY, Vosburg DA, Walsh CT, Hoch JC, Wagner G. Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins. J Am Chem Soc. 2006 May 3; 128(17):5757-63. PMID: 16637644; PMCID: PMC2527460.
    36. Sun ZY, Frueh DP, Selenko P, Hoch JC, Wagner G. Fast assignment of 15N-HSQC peaks using high-resolution 3D HNcocaNH experiments with non-uniform sampling. J Biomol NMR. 2005 Sep; 33(1):43-50. PMID: 16222556.
      View in: PubMed
    37. Teilum K, Hoch JC, Goffin V, Kinet S, Martial JA, Kragelund BB. Solution structure of human prolactin. J Mol Biol. 2005 Aug 26; 351(4):810-23. PMID: 16045928.
      View in: PubMed
    38. Sun ZY, Hyberts SG, Rovnyak D, Park S, Stern AS, Hoch JC, Wagner G. High-resolution aliphatic side-chain assignments in 3D HCcoNH experiments with joint H-C evolution and non-uniform sampling. J Biomol NMR. 2005 May; 32(1):55-60. PMID: 16041483.
      View in: PubMed
    39. Shimba N, Kovacs H, Stern AS, Nomura AM, Shimada I, Hoch JC, Craik CS, Dötsch V. Optimization of 13C direct detection NMR methods. J Biomol NMR. 2004 Oct; 30(2):175-9. PMID: 15557804.
      View in: PubMed
    40. Rovnyak D, Hoch JC, Stern AS, Wagner G. Resolution and sensitivity of high field nuclear magnetic resonance spectroscopy. J Biomol NMR. 2004 Sep; 30(1):1-10. PMID: 15452430.
      View in: PubMed
    41. Rovnyak D, Frueh DP, Sastry M, Sun ZY, Stern AS, Hoch JC, Wagner G. Accelerated acquisition of high resolution triple-resonance spectra using non-uniform sampling and maximum entropy reconstruction. J Magn Reson. 2004 Sep; 170(1):15-21. PMID: 15324754.
      View in: PubMed
    42. Connolly PJ, Stern AS, Turner CJ, Hoch JC. Molecular dynamics of the long neurotoxin LSIII. Biochemistry. 2003 Dec 16; 42(49):14443-51. PMID: 14661955.
      View in: PubMed
    43. Shimba N, Stern AS, Craik CS, Hoch JC, Dötsch V. Elimination of 13Calpha splitting in protein NMR spectra by deconvolution with maximum entropy reconstruction. J Am Chem Soc. 2003 Mar 5; 125(9):2382-3. PMID: 12603112.
      View in: PubMed
    44. Rovnyak D, Filip C, Itin B, Stern AS, Wagner G, Griffin RG, Hoch JC. Multiple-quantum magic-angle spinning spectroscopy using nonlinear sampling. J Magn Reson. 2003 Mar; 161(1):43-55. PMID: 12660110.
      View in: PubMed
    45. Offredi F, Dubail F, Kischel P, Sarinski K, Stern AS, Van de Weerdt C, Hoch JC, Prosperi C, François JM, Mayo SL, Martial JA. De novo backbone and sequence design of an idealized alpha/beta-barrel protein: evidence of stable tertiary structure. J Mol Biol. 2003 Jan 3; 325(1):163-74. PMID: 12473459.
      View in: PubMed
    46. Stern AS, Li KB, Hoch JC. Modern spectrum analysis in multidimensional NMR spectroscopy: comparison of linear-prediction extrapolation and maximum-entropy reconstruction. J Am Chem Soc. 2002 Mar 6; 124(9):1982-93. PMID: 11866612.
      View in: PubMed
    47. Hoch JC, Stern AS. Maximum entropy reconstruction, spectrum analysis and deconvolution in multidimensional nuclear magnetic resonance. Methods Enzymol. 2001; 338:159-78. PMID: 11460547.
      View in: PubMed
    48. Li KB, Stern AS, Hoch JC. Distributed parallel processing for multidimensional maximum entropy reconstruction. J Magn Reson. 1998 Sep; 134(1):161-3. PMID: 9740743.
      View in: PubMed
    49. Schmieder P, Stern AS, Wagner G, Hoch JC. Quantification of maximum-entropy spectrum reconstructions. J Magn Reson. 1997 Apr; 125(2):332-9. PMID: 9144266.
      View in: PubMed
    50. Connolly PJ, Stern AS, Hoch JC. Solution structure of LSIII, a long neurotoxin from the venom of Laticauda semifasciata. Biochemistry. 1996 Jan 16; 35(2):418-26. PMID: 8555211.
      View in: PubMed
    51. Schmieder P, Stern AS, Wagner G, Hoch JC. Improved resolution in triple-resonance spectra by nonlinear sampling in the constant-time domain. J Biomol NMR. 1994 Jul; 4(4):483-90. PMID: 8075537.
      View in: PubMed
    52. Schmieder P, Stern AS, Wagner G, Hoch JC. Application of nonlinear sampling schemes to COSY-type spectra. J Biomol NMR. 1993 Sep; 3(5):569-76. PMID: 8219741.
      View in: PubMed
    53. Donoho DL, Johnstone IM, Stern AS, Hoch JC. Does the maximum entropy method improve sensitivity? Proc Natl Acad Sci U S A. 1990 Jul; 87(13):5066-8. PMID: 11607089; PMCID: PMC54262.
    54. Hoch JC. Modern spectrum analysis in nuclear magnetic resonance: alternatives to the Fourier transform. Methods Enzymol. 1989; 176:216-41. PMID: 2811688.
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    55. Hoch JC, Dobson CM, Karplus M. Vicinal coupling constants and protein dynamics. Biochemistry. 1985 Jul 16; 24(15):3831-41. PMID: 4052369.
      View in: PubMed
    56. Hoch JC, Dobson CM, Karplus M. Fluctuations and averaging of proton chemical shifts in the bovine pancreatic trypsin inhibitor. Biochemistry. 1982 Mar 16; 21(6):1118-25. PMID: 6280757.
      View in: PubMed
    57. Poulsen FM, Hoch JC, Dobson CM. A structural study of the hydrophobic box region of lysozyme in solution using nuclear Overhauser effects. Biochemistry. 1980 Jun 10; 19(12):2597-607. PMID: 7190435.
      View in: PubMed
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