Keywords
Last Name
Institution

Leslie I Wolfson MD

TitleProfessor and Chairman
InstitutionUConn Health Center
DepartmentNeurology
AddressMC 1840
MC 1840
263 Farmington Avenue
Phone860-679-3186
Fax860-679-4446
vCardDownload vCard
    Other Positions
    TitleDirector
    InstitutionHartford Hospital
    DepartmentNeurology


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Abraham HM, Wolfson L, Moscufo N, Guttmann CR, Kaplan RF, White WB. Cardiovascular risk factors and small vessel disease of the brain: Blood pressure, white matter lesions, and functional decline in older persons. J Cereb Blood Flow Metab. 2016 Jan; 36(1):132-42. PMID: 26036933.
      View in: PubMed
    2. Cavallari M, Moscufo N, Meier D, Skudlarski P, Pearlson GD, White WB, Wolfson L, Guttmann CR. Thalamic fractional anisotropy predicts accrual of cerebral white matter damage in older subjects with small-vessel disease. J Cereb Blood Flow Metab. 2014 Aug; 34(8):1321-7. PMID: 24824915; PMCID: PMC4126092.
    3. Papp KV, Kaplan RF, Springate B, Moscufo N, Wakefield DB, Guttmann CR, Wolfson L. Processing speed in normal aging: effects of white matter hyperintensities and hippocampal volume loss. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2014; 21(2):197-213. PMID: 23895570; PMCID: PMC3974573.
    4. Wolfson L, Wakefield DB, Moscufo N, Kaplan RF, Hall CB, Schmidt JA, Guttmann CR, White WB. Rapid buildup of brain white matter hyperintensities over 4 years linked to ambulatory blood pressure, mobility, cognition, and depression in old persons. J Gerontol A Biol Sci Med Sci. 2013 Nov; 68(11):1387-94. PMID: 23766429; PMCID: PMC3805298.
    5. Cavallari M, Moscufo N, Skudlarski P, Meier D, Panzer VP, Pearlson GD, White WB, Wolfson L, Guttmann CR. Mobility impairment is associated with reduced microstructural integrity of the inferior and superior cerebellar peduncles in elderly with no clinical signs of cerebellar dysfunction. Neuroimage Clin. 2013; 2:332-40. PMID: 24179787; PMCID: PMC3777843.
    6. White WB, Marfatia R, Schmidt J, Wakefield DB, Kaplan RF, Bohannon RW, Hall CB, Guttmann CR, Moscufo N, Fellows D, Wolfson L. INtensive versus standard ambulatory blood pressure lowering to prevent functional DeclINe in the ElderlY (INFINITY). Am Heart J. 2013 Mar; 165(3):258-265.e1. PMID: 23453090; PMCID: PMC3587966.
    7. White WB, Wolfson L, Wakefield DB, Hall CB, Campbell P, Moscufo N, Schmidt J, Kaplan RF, Pearlson G, Guttmann CR. Average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people. Circulation. 2011 Nov 22; 124(21):2312-9. PMID: 22105196; PMCID: PMC3235794.
    8. Panzer VP, Wakefield DB, Hall CB, Wolfson LI. Mobility assessment: sensitivity and specificity of measurement sets in older adults. Arch Phys Med Rehabil. 2011 Jun; 92(6):905-12. PMID: 21621667; PMCID: PMC3146767.
    9. Bauer LO, Wu Z, Wolfson LI. An obese body mass increases the adverse effects of HIV/AIDS on balance and gait. Phys Ther. 2011 Jul; 91(7):1063-71. PMID: 21527386; PMCID: PMC3129518.
    10. Moscufo N, Wolfson L, Meier D, Liguori M, Hildenbrand PG, Wakefield D, Schmidt JA, Pearlson GD, Guttmann CR. Mobility decline in the elderly relates to lesion accrual in the splenium of the corpus callosum. Age (Dordr). 2012 Apr; 34(2):405-14. PMID: 21505765; PMCID: PMC3312641.
    11. Zeevi N, Pachter J, McCullough LD, Wolfson L, Kuchel GA. The blood-brain barrier: geriatric relevance of a critical brain-body interface. J Am Geriatr Soc. 2010 Sep; 58(9):1749-57. PMID: 20863334.
      View in: PubMed
    12. Campbell P, Ghuman N, Wakefield D, Wolfson L, White WB. Long-term reproducibility of ambulatory blood pressure is superior to office blood pressure in the very elderly. J Hum Hypertens. 2010 Nov; 24(11):749-54. PMID: 20200549; PMCID: PMC2888732.
    13. Wakefield DB, Moscufo N, Guttmann CR, Kuchel GA, Kaplan RF, Pearlson G, Wolfson L. White matter hyperintensities predict functional decline in voiding, mobility, and cognition in older adults. J Am Geriatr Soc. 2010 Feb; 58(2):275-81. PMID: 20374403; PMCID: PMC3764600.
    14. Masdeu JC, Wolfson L. White matter lesions predispose to falls in older people. Stroke. 2009 Sep; 40(9):e546. PMID: 19628802.
      View in: PubMed
    15. Moscufo N, Guttmann CR, Meier D, Csapo I, Hildenbrand PG, Healy BC, Schmidt JA, Wolfson L. Brain regional lesion burden and impaired mobility in the elderly. Neurobiol Aging. 2011 Apr; 32(4):646-54. PMID: 19428145; PMCID: PMC2942957.
    16. Kuchel GA, Moscufo N, Guttmann CR, Zeevi N, Wakefield D, Schmidt J, Dubeau CE, Wolfson L. Localization of brain white matter hyperintensities and urinary incontinence in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2009 Aug; 64(8):902-9. PMID: 19386575; PMCID: PMC2709544.
    17. Kaplan RF, Cohen RA, Moscufo N, Guttmann C, Chasman J, Buttaro M, Hall CH, Wolfson L. Demographic and biological influences on cognitive reserve. J Clin Exp Neuropsychol. 2009 Oct; 31(7):868-76. PMID: 19333862.
      View in: PubMed
    18. Wolfson L. Microalbuminurea as an index of brain microvascular dysfunction. J Neurol Sci. 2008 Sep 15; 272(1-2):34-5. PMID: 18539299.
      View in: PubMed
    19. Wolfson L, Wei X, Hall CB, Panzer V, Wakefield D, Benson RR, Schmidt JA, Warfield SK, Guttmann CR. Accrual of MRI white matter abnormalities in elderly with normal and impaired mobility. J Neurol Sci. 2005 May 15; 232(1-2):23-7. PMID: 15850578.
      View in: PubMed
    20. Bauer LO, Ceballos NA, Shanley JD, Wolfson LI. Sensorimotor dysfunction in HIV/AIDS: effects of antiretroviral treatment and comorbid psychiatric disorders. AIDS. 2005 Mar 25; 19(5):495-502. PMID: 15764855; PMCID: PMC1255907.
    21. Pacelli JP, Wolfson L. Neurologic assessment and therapy of patients with impaired mobility. Conn Med. 2003 Sep; 67(8):475-9. PMID: 14587127.
      View in: PubMed
    22. King MB, Whipple RH, Gruman CA, Judge JO, Schmidt JA, Wolfson LI. The Performance Enhancement Project: improving physical performance in older persons. Arch Phys Med Rehabil. 2002 Aug; 83(8):1060-9. PMID: 12161826.
      View in: PubMed
    23. Wei X, Warfield SK, Zou KH, Wu Y, Li X, Guimond A, Mugler JP, Benson RR, Wolfson L, Weiner HL, Guttmann CR. Quantitative analysis of MRI signal abnormalities of brain white matter with high reproducibility and accuracy. J Magn Reson Imaging. 2002 Feb; 15(2):203-9. PMID: 11836778.
      View in: PubMed
    24. Benson RR, Guttmann CR, Wei X, Warfield SK, Hall C, Schmidt JA, Kikinis R, Wolfson LI. Older people with impaired mobility have specific loci of periventricular abnormality on MRI. Neurology. 2002 Jan 8; 58(1):48-55. PMID: 11781405.
      View in: PubMed
    25. Kario K, Tobin JN, Wolfson LI, Whipple R, Derby CA, Singh D, Marantz PR, Wassertheil-Smoller S. Lower standing systolic blood pressure as a predictor of falls in the elderly: a community-based prospective study. J Am Coll Cardiol. 2001 Jul; 38(1):246-52. PMID: 11451282.
      View in: PubMed
    26. Wolfson L. Gait and balance dysfunction: a model of the interaction of age and disease. Neuroscientist. 2001 Apr; 7(2):178-83. PMID: 11496928.
      View in: PubMed
    27. Miller MD, Cornes C, Frank E, Ehrenpreis L, Silberman R, Schlernitzauer MA, Tracey B, Richards V, Wolfson L, Zaltman J, Bensasi S, Reynolds CF. Interpersonal psychotherapy for late-life depression: past, present, and future. J Psychother Pract Res. 2001; 10(4):231-8. PMID: 11696649; PMCID: PMC3330668.
    28. Schmidt JA, Gruman C, King MB, Wolfson LI. Attrition in an exercise intervention: a comparison of early and later dropouts. J Am Geriatr Soc. 2000 Aug; 48(8):952-60. PMID: 10968301.
      View in: PubMed
    29. Guttmann CR, Benson R, Warfield SK, Wei X, Anderson MC, Hall CB, Abu-Hasaballah K, Mugler JP, Wolfson L. White matter abnormalities in mobility-impaired older persons. Neurology. 2000 Mar 28; 54(6):1277-83. PMID: 10746598.
      View in: PubMed
    30. King MB, Judge JO, Whipple R, Wolfson L. Reliability and responsiveness of two physical performance measures examined in the context of a functional training intervention. Phys Ther. 2000 Jan; 80(1):8-16. PMID: 10623956.
      View in: PubMed
    31. Duckrow RB, Abu-Hasaballah K, Whipple R, Wolfson L. Stance perturbation-evoked potentials in old people with poor gait and balance. Clin Neurophysiol. 1999 Dec; 110(12):2026-32. PMID: 10616107.
      View in: PubMed
    32. Miller MD, Wolfson L, Frank E, Cornes C, Silberman R, Ehrenpreis L, Zaltman J, Malloy J, Reynolds CF. Using interpersonal psychotherapy (IPT) in a combined psychotherapy/medication research protocol with depressed elders. A descriptive report with case vignettes. J Psychother Pract Res. 1997; 7(1):47-55. PMID: 9407475; PMCID: PMC3330480.
    33. Felice KJ, Grunnet ML, Rao KR, Wolfson LI. Childhood-onset spinocerebellar syndrome associated with massive polyglucosan body deposition. Acta Neurol Scand. 1997 Jan; 95(1):60-4. PMID: 9048988.
      View in: PubMed
    34. Wolfson L, Whipple R, Derby C, Judge J, King M, Amerman P, Schmidt J, Smyers D. Balance and strength training in older adults: intervention gains and Tai Chi maintenance. J Am Geriatr Soc. 1996 May; 44(5):498-506. PMID: 8617896.
      View in: PubMed
    35. Wolfson L, Judge J, Whipple R, King M. Strength is a major factor in balance, gait, and the occurrence of falls. J Gerontol A Biol Sci Med Sci. 1995 Nov; 50 Spec No:64-7. PMID: 7493221.
      View in: PubMed
    36. Rossiter-Fornoff JE, Wolf SL, Wolfson LI, Buchner DM. A cross-sectional validation study of the FICSIT common data base static balance measures. Frailty and Injuries: Cooperative Studies of Intervention Techniques. J Gerontol A Biol Sci Med Sci. 1995 Nov; 50(6):M291-7. PMID: 7583799.
      View in: PubMed
    37. Judge JO, King MB, Whipple R, Clive J, Wolfson LI. Dynamic balance in older persons: effects of reduced visual and proprioceptive input. J Gerontol A Biol Sci Med Sci. 1995 Sep; 50(5):M263-70. PMID: 7671028.
      View in: PubMed
    38. King MB, Judge JO, Wolfson L. Functional base of support decreases with age. J Gerontol. 1994 Nov; 49(6):M258-63. PMID: 7963278.
      View in: PubMed
    39. Judge JO, Whipple RH, Wolfson LI. Effects of resistive and balance exercises on isokinetic strength in older persons. J Am Geriatr Soc. 1994 Sep; 42(9):937-46. PMID: 8064101.
      View in: PubMed
    40. Wolfson L, Whipple R, Derby CA, Amerman P, Nashner L. Gender differences in the balance of healthy elderly as demonstrated by dynamic posturography. J Gerontol. 1994 Jul; 49(4):M160-7. PMID: 8014390.
      View in: PubMed
    41. Whipple R, Wolfson L, Derby C, Singh D, Tobin J. Altered sensory function and balance in older persons. J Gerontol. 1993 Sep; 48 Spec No:71-6. PMID: 8409244.
      View in: PubMed
    42. Wolfson L, Whipple R, Judge J, Amerman P, Derby C, King M. Training balance and strength in the elderly to improve function. J Am Geriatr Soc. 1993 Mar; 41(3):341-3. PMID: 8440862.
      View in: PubMed
    43. Wolfson L, Whipple R, Derby CA, Amerman P, Murphy T, Tobin JN, Nashner L. A dynamic posturography study of balance in healthy elderly. Neurology. 1992 Nov; 42(11):2069-75. PMID: 1436514.
      View in: PubMed
    44. Crystal HA, Dickson DW, Lizardi JE, Davies P, Wolfson LI. Antemortem diagnosis of diffuse Lewy body disease. Neurology. 1990 Oct; 40(10):1523-8. PMID: 2170865.
      View in: PubMed
    45. Wolfson L, Whipple R, Amerman P, Tobin JN. Gait assessment in the elderly: a gait abnormality rating scale and its relation to falls. J Gerontol. 1990 Jan; 45(1):M12-9. PMID: 2295773.
      View in: PubMed
    46. Masdeu JC, Wolfson L, Lantos G, Tobin JN, Grober E, Whipple R, Amerman P. Brain white-matter changes in the elderly prone to falling. Arch Neurol. 1989 Dec; 46(12):1292-6. PMID: 2590013.
      View in: PubMed
    47. Crystal H, Dickson D, Fuld P, Masur D, Scott R, Mehler M, Masdeu J, Kawas C, Aronson M, Wolfson L. Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology. 1988 Nov; 38(11):1682-7. PMID: 3185902.
      View in: PubMed
    48. Whipple RH, Wolfson LI, Amerman PM. The relationship of knee and ankle weakness to falls in nursing home residents: an isokinetic study. J Am Geriatr Soc. 1987 Jan; 35(1):13-20. PMID: 3794141.
      View in: PubMed
    49. Wolfson LI, Whipple R, Amerman P, Kleinberg A. Stressing the postural response. A quantitative method for testing balance. J Am Geriatr Soc. 1986 Dec; 34(12):845-50. PMID: 3782696.
      View in: PubMed
    50. Masdeu JC, Lantos G, Wolfson L. Hemispheric white matter lesions in the elderly prone to falling. Acta Radiol Suppl. 1986; 369:392. PMID: 2980506.
      View in: PubMed
    51. Wolfson LI, Leenders KL, Brown LL, Jones T. Alterations of regional cerebral blood flow and oxygen metabolism in Parkinson's disease. Neurology. 1985 Oct; 35(10):1399-405. PMID: 4033924.
      View in: PubMed
    52. Wolfson LI, Whipple R, Amerman P, Kaplan J, Kleinberg A. Gait and balance in the elderly. Two functional capacities that link sensory and motor ability to falls. Clin Geriatr Med. 1985 Aug; 1(3):649-59. PMID: 3913514.
      View in: PubMed
    53. Wolfson LI, Sharpless NS, Thal LJ, Waltz JM, Shapiro K. Decreased ventricular fluid norepinephrine metabolite in childhood-onset dystonia. Neurology. 1983 Mar; 33(3):369-72. PMID: 6681883.
      View in: PubMed
    54. Thal LJ, Wolfson LI. Functional anatomy of L-5-hydroxytryptophan-induced myoclonus in the guinea pig. Neurology. 1981 Aug; 31(8):955-60. PMID: 6973711.
      View in: PubMed
    55. Tabaddor K, Wolfson LI, Sharpless NS. Diminished ventricular fluid dopamine metabolites in adult-onset dystonia. Neurology. 1978 Dec; 28(12):1254-8. PMID: 569784.
      View in: PubMed
    56. Tabaddor K, Wolfson LI, Sharpless NS. Ventricular fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in patients with movement disorders. Neurology. 1978 Dec; 28(12):1249-53. PMID: 569783.
      View in: PubMed
    57. Wolfson LI, Escriva A. Clearance of 3-methoxy-4-hydroxyphenylglycol from the cerebrospinal fluid. Neurology. 1976 Aug; 26(8):781-4. PMID: 945873.
      View in: PubMed
    58. Wolfson LI, Katzman R, Escriva A. Clearance of amine metabolites from the cerebrospinal fluid: the brain as a "sink". Neurology. 1974 Aug; 24(8):772-9. PMID: 4858421.
      View in: PubMed
    59. Wolfson LI, Katzman R. Infusion manometric test in experimental subarachnoid hemorrhage in cats. Neurology. 1972 Aug; 22(8):856-62. PMID: 4673414.
      View in: PubMed
    Wolfson's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _