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Barbara E Kream PhD

TitleProfessor
InstitutionUConn Health Center
DepartmentMedicine
AddressMC 1850
MC 1850
263 Farmington Avenue
Phone860-679-3489
Fax860-679-1258
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cao J, Ou G, Yang N, Ding K, Kream BE, Hamrick MW, Isales CM, Shi XM. Impact of targeted PPAR? disruption on bone remodeling. Mol Cell Endocrinol. 2015 Jul 15; 410:27-34. PMID: 25666993; PMCID: PMC4444378 [Available on 07/15/16].
    2. Vang AG, Housley W, Dong H, Basole C, Ben-Sasson SZ, Kream BE, Epstein PM, Clark RB, Brocke S. Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. Biochem J. 2013 Dec 15; 456(3):463-73. PMID: 24007532.
      View in: PubMed
    3. Gillespie JR, Bush JR, Bell GI, Aubrey LA, Dupuis H, Ferron M, Kream B, DiMattia G, Patel S, Woodgett JR, Karsenty G, Hess DA, Beier F. GSK-3ß function in bone regulates skeletal development, whole-body metabolism, and male life span. Endocrinology. 2013 Oct; 154(10):3702-18. PMID: 23904355.
      View in: PubMed
    4. Yang W, Guo D, Harris MA, Cui Y, Gluhak-Heinrich J, Wu J, Chen XD, Skinner C, Nyman JS, Edwards JR, Mundy GR, Lichtler A, Kream BE, Rowe DW, Kalajzic I, David V, Quarles DL, Villareal D, Scott G, Ray M, Liu S, Martin JF, Mishina Y, Harris SE. Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells. J Cell Sci. 2013 Sep 15; 126(Pt 18):4085-98. PMID: 23843612; PMCID: PMC3772385.
    5. Khosla S, Bellido TM, Drezner MK, Gordon CM, Harris TB, Kiel DP, Kream BE, LeBoff MS, Lian JB, Peterson CA, Rosen CJ, Williams JP, Winer KK, Sherman SS. Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop. J Bone Miner Res. 2011 Nov; 26(11):2565-78. PMID: 21915901; PMCID: PMC3625440.
    6. Brennan-Speranza TC, Rizzoli R, Kream BE, Rosen C, Ammann P. Selective osteoblast overexpression of IGF-I in mice prevents low protein-induced deterioration of bone strength and material level properties. Bone. 2011 Nov; 49(5):1073-9. PMID: 21840432.
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    7. Bilezikian JP, Drezner M, Kream B, Stern P, Clemens T, Elderkin A, Siris E, Krane S, Eisman J, Arnold A, Feyen J, Hurley M, Kawaguchi H, Lorenzo J, Peck W, Pilbeam C, Rowe D, Martin TJ, Hock J, DeLuca H, Rodan S, Lukert B, Chen T, Klein-Nulend J. Lawrence G. Raisz November 13, 1925-August 25, 2010. J Bone Miner Res. 2011 May; 26(5):903-11. PMID: 21541991.
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    8. Zhang X, Tamasi J, Lu X, Zhu J, Chen H, Tian X, Lee TC, Threadgill DW, Kream BE, Kang Y, Partridge NC, Qin L. Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo. J Bone Miner Res. 2011 May; 26(5):1022-34. PMID: 21542005; PMCID: PMC3179301.
    9. Vang AG, Ben-Sasson SZ, Dong H, Kream B, DeNinno MP, Claffey MM, Housley W, Clark RB, Epstein PM, Brocke S. PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER. PLoS One. 2010; 5(8):e12011. PMID: 20711499; PMCID: PMC2918507.
    10. Yang M, Trettel LB, Adams DJ, Harrison JR, Canalis E, Kream BE. Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation. Bone. 2010 Sep; 47(3):573-82. PMID: 20541046; PMCID: PMC2926146.
    11. Huang H, Chikazu D, Voznesensky OS, Herschman HR, Kream BE, Drissi H, Pilbeam CC. Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway. J Bone Miner Res. 2010 Apr; 25(4):819-29. PMID: 19821778; PMCID: PMC3153333.
    12. Gluhak-Heinrich J, Guo D, Yang W, Harris MA, Lichtler A, Kream B, Zhang J, Feng JQ, Smith LC, Dechow P, Harris SE. New roles and mechanism of action of BMP4 in postnatal tooth cytodifferentiation. Bone. 2010 Jun; 46(6):1533-45. PMID: 20206312; PMCID: PMC2875306.
    13. Gaur T, Hussain S, Mudhasani R, Parulkar I, Colby JL, Frederick D, Kream BE, van Wijnen AJ, Stein JL, Stein GS, Jones SN, Lian JB. Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse. Dev Biol. 2010 Apr 1; 340(1):10-21. PMID: 20079730; PMCID: PMC2840721.
    14. Gao Q, Zhan P, Alander CB, Kream BE, Hao C, Breyer MD, Pilbeam CC, Raisz LG. Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice. Bone. 2009 Jul; 45(1):98-103. PMID: 19344793.
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    15. Yang M, Kream BE. Calcitonin induces expression of the inducible cAMP early repressor in osteoclasts. Endocrine. 2008 Jun; 33(3):245-53. PMID: 19016003; PMCID: PMC2858383.
    16. Chandhoke TK, Huang YF, Liu F, Gronowicz GA, Adams DJ, Harrison JR, Kream BE. Osteopenia in transgenic mice with osteoblast-targeted expression of the inducible cAMP early repressor. Bone. 2008 Jul; 43(1):101-9. PMID: 18460422; PMCID: PMC2474743.
    17. Notini AJ, McManus JF, Moore A, Bouxsein M, Jimenez M, Chiu WS, Glatt V, Kream BE, Handelsman DJ, Morris HA, Zajac JD, Davey RA. Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice. J Bone Miner Res. 2007 Mar; 22(3):347-56. PMID: 17147488.
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    18. Liu F, Lee SK, Adams DJ, Gronowicz GA, Kream BE. CREM deficiency in mice alters the response of bone to intermittent parathyroid hormone treatment. Bone. 2007 Apr; 40(4):1135-43. PMID: 17275432; PMCID: PMC1995436.
    19. Cochrane RL, Clark SH, Harris A, Kream BE. Rearrangement of a conditional allele regardless of inheritance of a Cre recombinase transgene. Genesis. 2007 Jan; 45(1):17-20. PMID: 17211878.
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    20. Sher LB, Harrison JR, Adams DJ, Kream BE. Impaired cortical bone acquisition and osteoblast differentiation in mice with osteoblast-targeted disruption of glucocorticoid signaling. Calcif Tissue Int. 2006 Aug; 79(2):118-25. PMID: 16927049.
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    21. Ivkosic A, Kronenberg MS, Lichtler AC, Kream BE. Analysis of internal deletions of a rat Col1a1 promoter fragment in transfected ROS17/2.8 cells. Coll Antropol. 2006 Jun; 30(2):401-4. PMID: 16848158.
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    22. Delahunty KM, Shultz KL, Gronowicz GA, Koczon-Jaremko B, Adamo ML, Horton LG, Lorenzo J, Donahue LR, Ackert-Bicknell C, Kream BE, Beamer WG, Rosen CJ. Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition. Endocrinology. 2006 Aug; 147(8):3915-23. PMID: 16675518.
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    23. Jiang J, Lichtler AC, Gronowicz GA, Adams DJ, Clark SH, Rosen CJ, Kream BE. Transgenic mice with osteoblast-targeted insulin-like growth factor-I show increased bone remodeling. Bone. 2006 Sep; 39(3):494-504. PMID: 16644298.
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    24. Lengner CJ, Steinman HA, Gagnon J, Smith TW, Henderson JE, Kream BE, Stein GS, Lian JB, Jones SN. Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. J Cell Biol. 2006 Mar 13; 172(6):909-21. PMID: 16533949; PMCID: PMC2063734.
    25. He J, Rosen CJ, Adams DJ, Kream BE. Postnatal growth and bone mass in mice with IGF-I haploinsufficiency. Bone. 2006 Jun; 38(6):826-35. PMID: 16427371.
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    26. Liu F, Huang YF, Kream BE. Identification of novel cAMP responsive element modulator (CREM) isoforms expressed by osteoblasts. Calcif Tissue Int. 2005 Aug; 77(2):91-5. PMID: 16059773.
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    27. Liu F, Woitge HW, Braut A, Kronenberg MS, Lichtler AC, Mina M, Kream BE. Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues. Int J Dev Biol. 2004 Sep; 48(7):645-53. PMID: 15470637.
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    28. Sher LB, Woitge HW, Adams DJ, Gronowicz GA, Krozowski Z, Harrison JR, Kream BE. Transgenic expression of 11beta-hydroxysteroid dehydrogenase type 2 in osteoblasts reveals an anabolic role for endogenous glucocorticoids in bone. Endocrinology. 2004 Feb; 145(2):922-9. PMID: 14617568.
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    29. Nervina JM, Tetradis S, Huang YF, Harrison D, Molina C, Kream BE. Expression of inducible cAMP early repressor is coupled to the cAMP-protein kinase A signaling pathway in osteoblasts. Bone. 2003 May; 32(5):483-90. PMID: 12753864.
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    30. Harrison JR, Woitge HW, Kream BE. Genetic approaches to determine the role of glucocorticoid signaling in osteoblasts. Endocrine. 2002 Feb; 17(1):37-42. PMID: 12014702.
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    31. Woitge H, Harrison J, Ivkosic A, Krozowski Z, Kream B. Cloning and in vitro characterization of alpha 1(I)-collagen 11 beta-hydroxysteroid dehydrogenase type 2 transgenes as models for osteoblast-selective inactivation of natural glucocorticoids. Endocrinology. 2001 Mar; 142(3):1341-8. PMID: 11181553.
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    32. Woitge HW, Kream BE. Calvariae from fetal mice with a disrupted Igf1 gene have reduced rates of collagen synthesis but maintain responsiveness to glucocorticoids. J Bone Miner Res. 2000 Oct; 15(10):1956-64. PMID: 11028448.
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    33. Bogdanovic Z, Huang YF, Dodig M, Clark SH, Lichtler AC, Kream BE. Parathyroid hormone inhibits collagen synthesis and the activity of rat col1a1 transgenes mainly by a cAMP-mediated pathway in mouse calvariae. J Cell Biochem. 2000 Feb; 77(1):149-58. PMID: 10679825.
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    34. Hurley MM, Tetradis S, Huang YF, Hock J, Kream BE, Raisz LG, Sabbieti MG. Parathyroid hormone regulates the expression of fibroblast growth factor-2 mRNA and fibroblast growth factor receptor mRNA in osteoblastic cells. J Bone Miner Res. 1999 May; 14(5):776-83. PMID: 10320526.
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    35. Tetradis S, Nervina JM, Nemoto K, Kream BE. Parathyroid hormone induces expression of the inducible cAMP early repressor in osteoblastic MC3T3-E1 cells and mouse calvariae. J Bone Miner Res. 1998 Dec; 13(12):1846-51. PMID: 9844102.
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    36. Huang YF, Harrison JR, Lorenzo JA, Kream BE. Parathyroid hormone induces interleukin-6 heterogeneous nuclear and messenger RNA expression in murine calvarial organ cultures. Bone. 1998 Oct; 23(4):327-32. PMID: 9763144.
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    37. Bedalov A, Salvatori R, Dodig M, Kapural B, Pavlin D, Kream BE, Clark SH, Woody CO, Rowe DW, Lichtler AC. 1,25-Dihydroxyvitamin D3 inhibition of col1a1 promoter expression in calvariae from neonatal transgenic mice. Biochim Biophys Acta. 1998 Jul 9; 1398(3):285-93. PMID: 9655920.
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    38. Harrison JR, Kleinert LM, Kelly PL, Krebsbach PH, Woody C, Clark S, Rowe DW, Lichtler AC, Kream BE. Interleukin-1 represses COLIA1 promoter activity in calvarial bones of transgenic ColCAT mice in vitro and in vivo. J Bone Miner Res. 1998 Jul; 13(7):1076-83. PMID: 9661071.
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    39. Tetradis S, Pilbeam CC, Liu Y, Herschman HR, Kream BE. Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3',5'-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells. Endocrinology. 1997 Sep; 138(9):3594-600. PMID: 9275040.
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    40. Kream BE, Tetradis S, Lafrancis D, Fall PM, Feyen JH, Raisz LG. Modulation of the effects of glucocorticoids on collagen synthesis in fetal rat calvariae by insulin-like growth factor binding protein-2. J Bone Miner Res. 1997 Jun; 12(6):889-95. PMID: 9169346.
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    41. Advani S, LaFrancis D, Bogdanovic E, Taxel P, Raisz LG, Kream BE. Dexamethasone suppresses in vivo levels of bone collagen synthesis in neonatal mice. Bone. 1997 Jan; 20(1):41-6. PMID: 8988346.
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    42. Tetradis S, Pilbeam CC, Liu Y, Kream BE. Parathyroid hormone induces prostaglandin G/H synthase-2 expression by a cyclic adenosine 3',5'-monophosphate-mediated pathway in the murine osteoblastic cell line MC3T3-E1. Endocrinology. 1996 Dec; 137(12):5435-40. PMID: 8940368.
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    43. Dodig M, Kronenberg MS, Bedalov A, Kream BE, Gronowicz G, Clark SH, Mack K, Liu YH, Maxon R, Pan ZZ, Upholt WB, Rowe DW, Lichtler AC. Identification of a TAAT-containing motif required for high level expression of the COL1A1 promoter in differentiated osteoblasts of transgenic mice. J Biol Chem. 1996 Jul 5; 271(27):16422-9. PMID: 8663211.
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    44. Bedalov A, Salvatori R, Dodig M, Kronenberg MS, Kapural B, Bogdanovic Z, Kream BE, Woody CO, Clark SH, Mack K, et al. Regulation of COL1A1 expression in type I collagen producing tissues: identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice. J Bone Miner Res. 1995 Oct; 10(10):1443-51. PMID: 8686499.
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    45. Kream BE, Harrison JR, Krebsbach PH, Bogdanovic Z, Bedalov A, Pavlin D, Woody CO, Clark SH, Rowe D, Lichtler AC. Regulation of type I collagen gene expression in bone. Connect Tissue Res. 1995; 31(4):261-4. PMID: 15612364.
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    46. Pavlin D, Bedalov A, Kronenberg MS, Kream BE, Rowe DW, Smith CL, Pike JW, Lichtler AC. Analysis of regulatory regions in the COL1A1 gene responsible for 1,25-dihydroxyvitamin D3-mediated transcriptional repression in osteoblastic cells. J Cell Biochem. 1994 Dec; 56(4):490-501. PMID: 7890807.
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    47. Lichtler A, Stover ML, Angilly J, Kream B, Rowe DW. Isolation and characterization of the rat alpha 1(I) collagen promoter. Regulation by vitamin D. J Biol Chem. 1994 Jun 10; 269(23):16518. PMID: 8206963.
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    48. Bedalov A, Breault DT, Sokolov BP, Lichtler AC, Bedalov I, Clark SH, Mack K, Khillan JS, Woody CO, Kream BE, et al. Regulation of the alpha 1(I) collagen promoter in vascular smooth muscle cells. Comparison with other alpha 1(I) collagen-producing cells in transgenic animals and cultured cells. J Biol Chem. 1994 Feb 18; 269(7):4903-9. PMID: 8106463.
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    49. Bogdanovic Z, Bedalov A, Krebsbach PH, Pavlin D, Woody CO, Clark SH, Thomas HF, Rowe DW, Kream BE, Lichtler AC. Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice. J Bone Miner Res. 1994 Feb; 9(2):285-92. PMID: 8024654.
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    50. Raisz LG, Fall PM, Gabbitas BY, McCarthy TL, Kream BE, Canalis E. Effects of prostaglandin E2 on bone formation in cultured fetal rat calvariae: role of insulin-like growth factor-I. Endocrinology. 1993 Oct; 133(4):1504-10. PMID: 7691577.
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    51. Krebsbach PH, Harrison JR, Lichtler AC, Woody CO, Rowe DW, Kream BE. Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cells. Mol Cell Biol. 1993 Sep; 13(9):5168-74. PMID: 8355676; PMCID: PMC360205.
    52. Hurley MM, Abreu C, Harrison JR, Lichtler AC, Raisz LG, Kream BE. Basic fibroblast growth factor inhibits type I collagen gene expression in osteoblastic MC3T3-E1 cells. J Biol Chem. 1993 Mar 15; 268(8):5588-93. PMID: 8449921.
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    53. Kream BE, LaFrancis D, Petersen DN, Woody C, Clark S, Rowe DW, Lichtler A. Parathyroid hormone represses alpha 1(I) collagen promoter activity in cultured calvariae from neonatal transgenic mice. Mol Endocrinol. 1993 Mar; 7(3):399-408. PMID: 8483479.
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    54. Raisz LG, Fall PM, Petersen DN, Lichtler A, Kream BE. Prostaglandin E2 inhibits alpha 1(I)procollagen gene transcription and promoter activity in the immortalized rat osteoblastic clonal cell line Py1a. Mol Endocrinol. 1993 Jan; 7(1):17-22. PMID: 8446104.
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    55. Pavlin D, Lichtler AC, Bedalov A, Kream BE, Harrison JR, Thomas HF, Gronowicz GA, Clark SH, Woody CO, Rowe DW. Differential utilization of regulatory domains within the alpha 1(I) collagen promoter in osseous and fibroblastic cells. J Cell Biol. 1992 Jan; 116(1):227-36. PMID: 1730746; PMCID: PMC2289260.
    56. Zernik J, Kream B, Twarog K. Tissue-specific and dexamethasone-inducible expression of alkaline phosphatase from alternative promoters of the rat bone/liver/kidney/placenta gene. Biochem Biophys Res Commun. 1991 May 15; 176(3):1149-56. PMID: 2039500.
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    57. Lukert B, Mador A, Raisz LG, Kream BE. The role of DNA synthesis in the responses of fetal rat calvariae to cortisol. J Bone Miner Res. 1991 May; 6(5):453-60. PMID: 1906221.
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    58. Hurley MM, Kream BE, Raisz LG. Structural determinants of the capacity of heparin to inhibit collagen synthesis in 21-day fetal rat calvariae. J Bone Miner Res. 1990 Nov; 5(11):1127-33. PMID: 2176772.
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    59. Kream BE, Petersen DN, Raisz LG. Cortisol enhances the anabolic effects of insulin-like growth factor I on collagen synthesis and procollagen messenger ribonucleic acid levels in cultured 21-day fetal rat calvariae. Endocrinology. 1990 Mar; 126(3):1576-83. PMID: 2307119.
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    60. Hurley MM, Gronowicz G, Kream BE, Raisz LG. Effect of heparin on bone formation in cultured fetal rat calvaria. Calcif Tissue Int. 1990 Mar; 46(3):183-8. PMID: 2106377.
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    61. Harrison JR, Vargas SJ, Petersen DN, Lorenzo JA, Kream BE. Interleukin-1 alpha and phorbol ester inhibit collagen synthesis in osteoblastic MC3T3-E1 cells by a transcriptional mechanism. Mol Endocrinol. 1990 Feb; 4(2):184-90. PMID: 2329998.
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    62. Hurley MM, Martin DL, Kream BE, Raisz LG. Effects of ethanol and acetaldehyde on collagen synthesis, prostaglandin release and resorption of fetal rat bone in organ culture. Bone. 1990; 11(1):47-51. PMID: 2331431.
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    63. Kream BE, Petersen DN, Raisz LG. Parathyroid hormone blocks the stimulatory effect of insulin-like growth factor-I on collagen synthesis in cultured 21-day fetal rat calvariae. Bone. 1990; 11(6):411-5. PMID: 1964062.
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    64. Hurley MM, Fall P, Harrison JR, Petersen DN, Kream BE, Raisz LG. Effects of transforming growth factor alpha and interleukin-1 on DNA synthesis, collagen synthesis, procollagen mRNA levels, and prostaglandin E2 production in cultured fetal rat calvaria. J Bone Miner Res. 1989 Oct; 4(5):731-6. PMID: 2816517.
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    65. Craig RG, Rowe DW, Petersen DN, Kream BE. Insulin increases the steady state level of alpha-1(I) procollagen mRNA in the osteoblast-rich segment of fetal rat calvaria. Endocrinology. 1989 Sep; 125(3):1430-7. PMID: 2667957.
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    66. Harrison JR, Petersen DN, Lichtler AC, Mador AT, Rowe DW, Kream BE. 1,25-Dihydroxyvitamin D3 inhibits transcription of type I collagen genes in the rat osteosarcoma cell line ROS 17/2.8. Endocrinology. 1989 Jul; 125(1):327-33. PMID: 2737151.
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    67. Lichtler A, Stover ML, Angilly J, Kream B, Rowe DW. Isolation and characterization of the rat alpha 1(I) collagen promoter. Regulation by 1,25-dihydroxyvitamin D. J Biol Chem. 1989 Feb 25; 264(6):3072-7. PMID: 2536733.
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    68. Kream B, Harrison J, Bailey R, Petersen D, Rowe D, Lichtler A. Hormonal regulation of collagen gene expression in osteoblastic cell-overview and new findings. Connect Tissue Res. 1989; 20(1-4):187-92. PMID: 2558841.
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    69. Nah HD, Rodgers BJ, Kulyk WM, Kream BE, Kosher RA, Upholt WB. In situ hybridization analysis of the expression of the type II collagen gene in the developing chicken limb bud. Coll Relat Res. 1988 Jul; 8(4):277-94. PMID: 2850886.
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    70. Hodge BO, Kream BE. Variable effects of dexamethasone on protein synthesis in clonal rat osteosarcoma cells. Endocrinology. 1988 May; 122(5):2127-33. PMID: 3162872.
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    71. Feyen JH, Petersen DN, Kream BE. Inhibition of bone collagen synthesis by the tumor promoter phorbol 12-myristate 13-acetate. J Bone Miner Res. 1988 Apr; 3(2):173-9. PMID: 3213612.
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    72. Kream BE, Rowe D, Smith MD, Maher V, Majeska R. Hormonal regulation of collagen synthesis in a clonal rat osteosarcoma cell line. Endocrinology. 1986 Nov; 119(5):1922-8. PMID: 3021431.
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    73. Kream BE, Smith MD, Canalis E, Raisz LG. Characterization of the effect of insulin on collagen synthesis in fetal rat bone. Endocrinology. 1985 Jan; 116(1):296-302. PMID: 3880543.
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    74. Genovese C, Rowe D, Kream B. Construction of DNA sequences complementary to rat alpha 1 and alpha 2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D. Biochemistry. 1984 Dec 4; 23(25):6210-6. PMID: 6395893.
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    75. Chyun YS, Kream BE, Raisz LG. Cortisol decreases bone formation by inhibiting periosteal cell proliferation. Endocrinology. 1984 Feb; 114(2):477-80. PMID: 6690287.
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    76. Eilon G, Trummel C, Kream B, Viola MV. New bone resorption stimulation factor elaborated by a human osteosarcoma cell line. Cancer Res. 1984 Jan; 44(1):209-14. PMID: 6606487.
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    77. Raisz LG, Kream BE. Regulation of bone formation (second of two parts). N Engl J Med. 1983 Jul 14; 309(2):83-9. PMID: 6343879.
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    78. Raisz LG, Kream BE. Regulation of bone formation. N Engl J Med. 1983 Jul 7; 309(1):29-35. PMID: 6343872.
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    79. Rowe DW, Kream BE. Regulation of collagen synthesis in fetal rat calvaria by 1,25-dihydroxyvitamin D3. J Biol Chem. 1982 Jul 25; 257(14):8009-15. PMID: 6896329.
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    80. Hock JM, Kream BE, Raisz LG. Autoradiographic study of the effect of 1,25-dihydroxyvitamin D3 on bone matrix synthesis in vitamin D replete rats. Calcif Tissue Int. 1982 Jul; 34(4):347-51. PMID: 6814724.
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    81. Kream BE, Raisz LG, Sandberg AL. Activation of serum complement inhibits collagen synthesis in fetal rat bone in organ culture. Calcif Tissue Int. 1982 Jul; 34(4):370-5. PMID: 6814726.
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    82. Raisz LG, Kream BE. Hormonal control of skeletal growth. Annu Rev Physiol. 1981; 43:225-38. PMID: 7011182.
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    83. Kream BE, Rowe DW, Gworek SC, Raisz LG. Parathyroid hormone alters collagen synthesis and procollagen mRNA levels in fetal rat calvaria. Proc Natl Acad Sci U S A. 1980 Oct; 77(10):5654-8. PMID: 6934501; PMCID: PMC350127.
    84. Raisz LG, Kream BE, Smith MD, Simmons HA. Comparison of the effects of vitamin D metabolites on collagen synthesis and resportion of fetal rat bone in organ culture. Calcif Tissue Int. 1980; 32(2):135-8. PMID: 6773630.
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    85. Raisz LG, Vanderhoek JY, Simmons HA, Kream BE, Nicolaou KC. Prostaglandin synthesis by fetal rat bone in vitro: evidence for a role of prostacyclin. Prostaglandins. 1979 Jun; 17(6):905-14. PMID: 388530.
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    86. Raisz LG, Lorenzo J, Gworek S, Kream B, Rosenblatt M. Comparison of the effects of a potent synthetic analog of bovine parathyroid hormone with native bPTH-(1-84) and synthetic bPTH-(1-34) on bone resorption and collagen synthesis. Calcif Tissue Int. 1979; 29(3):215-8. PMID: 117885.
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    87. Kream BE, DeLuca HF, Moriarity DM, Kendrick NC, Ghazarian JG. Origin of 25-hydroxyvitamin D3 binding protein from tissue cytosol preparations. Arch Biochem Biophys. 1979 Jan; 192(1):318-23. PMID: 434824.
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    88. Ghazarian JG, Kream B, Botham KM, Nickells MW, DeLuca HF. Rat plasma 25-hydroxyvitamin D3 binding protein: an inhibitor of the 25-hydroxyvitamin D3-1alpha-hydroxylase. Arch Biochem Biophys. 1978 Jul; 189(1):212-20. PMID: 708045.
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    89. Raisz LG, Canalis EM, Dietrich JW, Kream BE, Gworek SC. Hormonal regulation of bone formation. Recent Prog Horm Res. 1978; 34:335-56. PMID: 366683.
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    90. Chesney RW, Horowitz SD, Kream BE, Eisman JA, Hong R, DeLuca HF. Failure of conventional doses of 1 alpha, 25-dihydroxycholecalciferol to correct hypocalcemia in a girl with idiopathic hypoparathyroidism. N Engl J Med. 1977 Dec 8; 297(23):1272-5. PMID: 917074.
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    91. Kream BE, Sauer LA. Pregnenolone-binding proteins in the rat adrenal cortex. Endocrinology. 1977 Oct; 101(4):1318-24. PMID: 908279.
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    92. Kream BE, Jose M, Yamada S, DeLuca HF. A specific high-affinity binding macromolecule for 1,25-dihydroxyvitamin D3 in fetal bone. Science. 1977 Sep 9; 197(4308):1086-8. PMID: 887939.
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    93. Kream BE, Yamada S, Schnoes HK, DeLuca HF. Specific cytosol-binding protein for 1,25-dihydroxyvitamin D3 in rat intestine. J Biol Chem. 1977 Jul 10; 252(13):4501-5. PMID: 873901.
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    94. Kream BE, DeLuca HF. A specific binding protein for 1,25-dihydroxyvitamin D3 in rat intestinal cytosol. Biochem Biophys Res Commun. 1977 Jun 6; 76(3):735-8. PMID: 197923.
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    95. Kream BE, Jose MJ, DeLuca HF. The chick intestinal cytosol binding protein for 1,25-dihydroxyvitamin D3: a study of analog binding. Arch Biochem Biophys. 1977 Mar; 179(2):462-8. PMID: 851354.
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    96. Kream BE, Reynolds RD, Knutson JC, Eisman JA, DeLuca HF. Intestinal cytosol binders of 1,25-dihydroxyvitamin D and 25-hydroxyvitamin D. Arch Biochem Biophys. 1976 Oct; 176(2):779-87. PMID: 984855.
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    97. Eisman JA, Hamstra AJ, Kream BE, DeLuca HF. 1,25-Dihydroxyvitamin D in biological fluids: a simplified and sensitive assay. Science. 1976 Sep 10; 193(4257):1021-3. PMID: 1085035.
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    98. Eisman JA, Hamstra AJ, Kream BE, DeLuca HF. A sensitive, precise, and convenient method for determination of 1,25-dihydroxyvitamin D in human plasma. Arch Biochem Biophys. 1976 Sep; 176(1):235-43. PMID: 9906.
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    99. Kream BE, Sauer LA. On the intracellular localization of the 3beta-hydroxysteroid dehydrogenase isomerase in the rat adrenal cortex. Proc Soc Exp Biol Med. 1976 Jul; 152(3):459-62. PMID: 181764.
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    100. Botham KM, Ghazarian JG, Kream BE, DeLuca HF. Isolation of an inhibitor of 25-hydroxyvitamin D3-1-hydroxylase from rat serum. Biochemistry. 1976 May 18; 15(10):2130-5. PMID: 1276129.
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