Keywords
Last Name
Institution

Cato T Laurencin MD, PhD

TitleUniversity Professor
InstitutionUniversity of Connecticut
AddressMC 3711
Academic Research Building, MC 3711
263 Farmington Avenue
Phone860-679-2594
Fax860-679-1533
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    Other Positions
    TitleAlbert and Wilda Van Dusen Distinguished Professor of Orthopaedic Surgery
    InstitutionUConn Health Center
    DepartmentOrthopaedic Surgery

    TitleProfessor
    InstitutionUniversity of Connecticut
    DepartmentChemical, Materials and Biomolecular Engineering

    TitleDirector
    InstitutionUConn Health Center
    DepartmentInstitute for Regenerative Engineering

    TitleDirector
    InstitutionUniversity of Connecticut
    DepartmentThe Raymond and Beverly Sackler Center for Biomedical, Biological, Engineering and Physical Sciences


    Collapse Biography 
    Collapse awards and honors
    1997Fellow, American Academy of Orthopaedic Surgeons
    2004Elected Member of the National Academy of Sciences, Institute of Medicine
    2006America’s Top Surgeons
    2006Nicolas Andry Award, American Association of Bone and Joint Surgeons
    2007Robert A. Bland Award, University of Virginia College of Engineering
    2007Who’s Who in Engineering Higher Education, Academic Keys
    2008One of the Top 50 Innovators, Scientific American
    2009Pierre Galletti Award (Organization’s Highest Award), American Institute for Medical and Biol
    2009Presidential Award of Excellence in Science, Engineering and Math Mentoring , Presented by President Barack Obama, January 2010
    2009Diversity Award, Biomedical Engineering Society's (BMES
    2011Elected Member, The African Academy of Sciences
    2011Elected Member, The National Academy of Engineering
    2012 Dr. Martin Luther King, Jr. Leadership Award, Massachusetts Institute of Technology
    2012Elizabeth Hurlock Beckman Award for inspiring their former students to make a significant contributi, The Elizabeth Hurlock Beckman Award Advisory Committee
    2012Regenerative Medicine among the “100 Scientific Discoveries That Changed the World”, National Geographic Magazine
    20132012 AAAS Mentor Award, The American Association for the Advancement of Science
    2013Technology, Innovation and Development Award, The Society for Biomaterials

    Collapse Overview 
    Collapse overview
    Dr. Laurencin is a designated University Professor; a tenured member of the faculty in the School of Engineering; and is Professor of Chemical and Biomolecular Engineering, Professor of Materials Engineering and Professor of Biomedical Engineering at UCONN. Dr. Laurencin serves as Chief Executive Officer of the Connecticut Institute for Clinical and Translational Science, UCONN’s Cross-University translational science institute. In addition, he is the Founding Director of the Institute for Regenerative Engineering and the Founding Director of the Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences at the UCONN Heath Center.

    He is the Albert and Wilda Van Dusen Distinguished Endowed Chair Professor of Orthopaedic Surgery in the School of Medicine. Also, Dr. Laurencin is an elected member of the Institute of Medicine of the National Academy of Sciences and an elected member of the National Academy of Engineering.

    Dr. Laurencin previously served as the UConn Health Center’s Vice President for Health Affairs and Dean of the UConn School of Medicine. Prior to that, Dr. Laurencin was the Lillian T. Pratt Distinguished Professor and chair of the Department of Orthopaedic Surgery at the University of Virginia, as well as the Orthopaedic Surgeon-in-Chief at the University of Virginia Health System. In addition, he was designated as a University Professor at the University of Virginia by the President of UVa, and held professorships in Biomedical Engineering and Chemical Engineering. Dr. Laurencin earned his undergraduate degree in chemical engineering from Princeton University and his medical degree, Magna Cum Laude from the Harvard Medical School. During medical school, he also earned his Ph.D. in biochemical engineering/biotechnology from the Massachusetts Institute of Technology.

    An expert in shoulder and knee surgery, Dr. Laurencin has been named to America’s Top Doctors, and America’s Top Surgeons; is widely published in scholarly journals; and holds more than 20 U.S. patents.. He is a Fellow of the American College of Surgeons, a Fellow of the American Academy of Orthopaedic surgeons and is one of few orthopaedic surgeons elected to the American Surgical Association. He is the winner of the Nicolas Andry Award from the Association of Bone and Joint Surgeons.

    He currently holds appointments by the Secretary of Health and Human Services to the National Advisory Council for Biomedical Imaging and Bioengineering, and the Advisory Committee to the Director of the National Institutes of Health.



    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. James R, Laurencin CT. Nanofiber technology: its transformative role in nanomedicine. Nanomedicine (Lond). 2016 Jun; 11(12):1499-501. PMID: 27246812.
      View in: PubMed
    2. Laurencin CT, Nair LS. The Quest toward limb regeneration: a regenerative engineering approach. Regen Biomater. 2016 Jun; 3(2):123-5. PMID: 27047679.
      View in: PubMed
    3. Kuyinu EL, Narayanan G, Nair LS, Laurencin CT. Animal models of osteoarthritis: classification, update, and measurement of outcomes. J Orthop Surg Res. 2016; 11(1):19. PMID: 26837951.
      View in: PubMed
    4. Pinn VW, Laurencin CT. The Fight for the Elimination of Racial and Ethnic Health Disparities: Acknowledging the Work and Celebrating the Life of Mr. Louis Stokes. J Racial Ethn Health Disparities. 2015 Dec; 2(4):423-4. PMID: 26863549.
      View in: PubMed
    5. Yu X, Tang X, Gohil SV, Laurencin CT. Biomaterials for Bone Regenerative Engineering. Adv Healthc Mater. 2015 Jun 24; 4(9):1268-85. PMID: 25846250; PMCID: PMC4507442 [Available on 06/01/16].
    6. Bagshaw KR, Hanenbaum CL, Carbone EJ, Lo KW, Laurencin CT, Walker J, Nair LS. Pain management via local anesthetics and responsive hydrogels. Ther Deliv. 2015 Feb; 6(2):165-76. PMID: 25690085; PMCID: PMC4500150 [Available on 12/01/15].
    7. Nelson C, Khan Y, Laurencin CT. Nanofiber-microsphere (nano-micro) matrices for bone regenerative engineering: a convergence approach toward matrix design. Regen Biomater. 2014 Nov; 1(1):3-9. PMID: 26816620.
      View in: PubMed
    8. Cushnie EK, Ulery BD, Nelson SJ, Deng M, Sethuraman S, Doty SB, Lo KW, Khan YM, Laurencin CT. Simple signaling molecules for inductive bone regenerative engineering. PLoS One. 2014; 9(7):e101627. PMID: 25019622; PMCID: PMC4096515.
    9. Mikael PE, Amini AR, Basu J, Josefina Arellano-Jimenez M, Laurencin CT, Sanders MM, Barry Carter C, Nukavarapu SP. Functionalized carbon nanotube reinforced scaffolds for bone regenerative engineering: fabrication, in vitro and in vivo evaluation. Biomed Mater. 2014 Jun; 9(3):035001. PMID: 24687391.
      View in: PubMed
    10. Laurencin CT, Ashe KM, Henry N, Kan HM, Lo KW. Delivery of small molecules for bone regenerative engineering: preclinical studies and potential clinical applications. Drug Discov Today. 2014 Jun; 19(6):794-800. PMID: 24508820; PMCID: PMC4048776.
    11. Lo KW, Jiang T, Gagnon KA, Nelson C, Laurencin CT. Small-molecule based musculoskeletal regenerative engineering. Trends Biotechnol. 2014 Feb; 32(2):74-81. PMID: 24405851; PMCID: PMC3992320.
    12. Ulery BD, Kan HM, Williams BA, Narasimhan B, Lo KW, Nair LS, Laurencin CT. Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics. Adv Healthc Mater. 2014 Jun; 3(6):843-7. PMID: 24376136; PMCID: PMC4053479.
    13. Lv Q, Deng M, Ulery BD, Nair LS, Laurencin CT. Nano-ceramic composite scaffolds for bioreactor-based bone engineering. Clin Orthop Relat Res. 2013 Aug; 471(8):2422-33. PMID: 23436161; PMCID: PMC3705070.
    14. Lo KW, Kan HM, Laurencin CT. Short-term administration of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells. J Tissue Eng Regen Med. 2016 Jun; 10(6):518-26. PMID: 23913855.
      View in: PubMed
    15. Jiang T, Deng M, James R, Nair LS, Laurencin CT. Micro- and nanofabrication of chitosan structures for regenerative engineering. Acta Biomater. 2014 Apr; 10(4):1632-45. PMID: 23851172.
      View in: PubMed
    16. Aravamudhan A, Ramos DM, Nip J, Harmon MD, James R, Deng M, Laurencin CT, Yu X, Kumbar SG. Cellulose and collagen derived micro-nano structured scaffolds for bone tissue engineering. J Biomed Nanotechnol. 2013 Apr; 9(4):719-31. PMID: 23621034.
      View in: PubMed
    17. Foley PL, Ulery BD, Kan HM, Burks MV, Cui Z, Wu Q, Nair LS, Laurencin CT. A chitosan thermogel for delivery of ropivacaine in regional musculoskeletal anesthesia. Biomaterials. 2013 Mar; 34(10):2539-46. PMID: 23321347.
      View in: PubMed
    18. Laurencin CT, Lo KW. Bone morphogenetic proteins for bone regeneration and their alternatives. Curr Pharm Des. 2013; 19(19):3353. PMID: 23432681.
      View in: PubMed
    19. Laurencin CT, Khan Y. Regenerative engineering. Sci Transl Med. 2012 Nov 14; 4(160):160ed9. PMID: 23152324.
      View in: PubMed
    20. Jabbarzadeh E, Deng M, Lv Q, Jiang T, Khan YM, Nair LS, Laurencin CT. VEGF-incorporated biomimetic poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering. J Biomed Mater Res B Appl Biomater. 2012 Nov; 100(8):2187-96. PMID: 22915492.
      View in: PubMed
    21. Lo KW, Ulery BD, Kan HM, Ashe KM, Laurencin CT. Evaluating the feasibility of utilizing the small molecule phenamil as a novel biofactor for bone regenerative engineering. J Tissue Eng Regen Med. 2014 Sep; 8(9):728-36. PMID: 22815259.
      View in: PubMed
    22. Lo KW, Ashe KM, Kan HM, Laurencin CT. The role of small molecules in musculoskeletal regeneration. Regen Med. 2012 Jul; 7(4):535-49. PMID: 22817627.
      View in: PubMed
    23. Peach MS, James R, Toti US, Deng M, Morozowich NL, Allcock HR, Laurencin CT, Kumbar SG. Polyphosphazene functionalized polyester fiber matrices for tendon tissue engineering: in vitro evaluation with human mesenchymal stem cells. Biomed Mater. 2012 Aug; 7(4):045016. PMID: 22736077.
      View in: PubMed
    24. McLaughlin SW, Cui Z, Starnes T, Laurencin CT, Kan HM, Wu Q, Nair LS. Injectable thermogelling chitosan for the local delivery of bone morphogenetic protein. J Mater Sci Mater Med. 2012 Sep; 23(9):2141-9. PMID: 22661244.
      View in: PubMed
    25. Amini AR, Adams DJ, Laurencin CT, Nukavarapu SP. Optimally porous and biomechanically compatible scaffolds for large-area bone regeneration. Tissue Eng Part A. 2012 Jul; 18(13-14):1376-88. PMID: 22401817.
      View in: PubMed
    26. Lo KW, Ulery BD, Ashe KM, Laurencin CT. Studies of bone morphogenetic protein-based surgical repair. Adv Drug Deliv Rev. 2012 Sep; 64(12):1277-91. PMID: 22512928; PMCID: PMC3401330.
    27. Amini AR, Laurencin CT, Nukavarapu SP. Differential analysis of peripheral blood- and bone marrow-derived endothelial progenitor cells for enhanced vascularization in bone tissue engineering. J Orthop Res. 2012 Sep; 30(9):1507-15. PMID: 22378621.
      View in: PubMed
    28. Peach MS, Kumbar SG, James R, Toti US, Balasubramaniam D, Deng M, Ulery B, Mazzocca AD, McCarthy MB, Morozowich NL, Allcock HR, Laurencin CT. Design and optimization of polyphosphazene functionalized fiber matrices for soft tissue regeneration. J Biomed Nanotechnol. 2012 Feb; 8(1):107-24. PMID: 22515099.
      View in: PubMed
    29. Deng M, James R, Laurencin CT, Kumbar SG. Nanostructured polymeric scaffolds for orthopaedic regenerative engineering. IEEE Trans Nanobioscience. 2012 Mar; 11(1):3-14. PMID: 22275722.
      View in: PubMed
    30. Amini AR, Laurencin CT, Nukavarapu SP. Bone tissue engineering: recent advances and challenges. Crit Rev Biomed Eng. 2012; 40(5):363-408. PMID: 23339648; PMCID: PMC3766369.
    31. Kumbar SG, Toti US, Deng M, James R, Laurencin CT, Aravamudhan A, Harmon M, Ramos DM. Novel mechanically competent polysaccharide scaffolds for bone tissue engineering. Biomed Mater. 2011 Dec; 6(6):065005. PMID: 22089383.
      View in: PubMed
    32. Ulery BD, Nair LS, Laurencin CT. Biomedical Applications of Biodegradable Polymers. J Polym Sci B Polym Phys. 2011 Jun 15; 49(12):832-864. PMID: 21769165.
      View in: PubMed
    33. James R, Kumbar SG, Laurencin CT, Balian G, Chhabra AB. Tendon tissue engineering: adipose-derived stem cell and GDF-5 mediated regeneration using electrospun matrix systems. Biomed Mater. 2011 Apr; 6(2):025011. PMID: 21436509; PMCID: PMC3206634.
    34. Bush JR, Nayak BK, Nair LS, Gupta MC, Laurencin CT. Improved bio-implant using ultrafast laser induced self-assembled nanotexture in titanium. J Biomed Mater Res B Appl Biomater. 2011 May; 97(2):299-305. PMID: 21394901.
      View in: PubMed
    35. Lo KW, Kan HM, Ashe KM, Laurencin CT. The small molecule PKA-specific cyclic AMP analogue as an inducer of osteoblast-like cells differentiation and mineralization. J Tissue Eng Regen Med. 2012 Jan; 6(1):40-8. PMID: 21312339; PMCID: PMC3133873.
    36. James R, Toti US, Laurencin CT, Kumbar SG. Electrospun nanofibrous scaffolds for engineering soft connective tissues. Methods Mol Biol. 2011; 726:243-58. PMID: 21424454.
      View in: PubMed
    37. Freeman JW, Woods MD, Cromer DA, Ekwueme EC, Andric T, Atiemo EA, Bijoux CH, Laurencin CT. Evaluation of a hydrogel-fiber composite for ACL tissue engineering. J Biomech. 2011 Feb 24; 44(4):694-9. PMID: 21111422.
      View in: PubMed
    38. Taylor ED, Nair LS, Nukavarapu SP, McLaughlin S, Laurencin CT. Novel nanostructured scaffolds as therapeutic replacement options for rotator cuff disease. J Bone Joint Surg Am. 2010 Dec; 92 Suppl 2:170-9. PMID: 21123600; PMCID: PMC2995583.
    39. El-Amin SF, Hogan MV, Allen AA, Hinds J, Laurencin CT. The indications and use of bone morphogenetic proteins in foot, ankle, and tibia surgery. Foot Ankle Clin. 2010 Dec; 15(4):543-51. PMID: 21056855.
      View in: PubMed
    40. Reichert WM, Ratner BD, Anderson J, Coury A, Hoffman AS, Laurencin CT, Tirrell D. 2010 Panel on the biomaterials grand challenges. J Biomed Mater Res A. 2011 Feb; 96(2):275-87. PMID: 21171147; PMCID: PMC4076103.
    41. Lewis KK, Bertolini MT, Hogan MJ, Laurencin C, Pettit CA, Purcaro MJ, Staub C, Williams MJ, Galvin JR. The new health-care system: results of a round table discussion. Conn Med. 2010 Nov-Dec; 74(10):609-13. PMID: 21189718.
      View in: PubMed
    42. Lo KW, Ashe KM, Kan HM, Lee DA, Laurencin CT. Activation of cyclic amp/protein kinase: a signaling pathway enhances osteoblast cell adhesion on biomaterials for regenerative engineering. J Orthop Res. 2011 Apr; 29(4):602-8. PMID: 20957743.
      View in: PubMed
    43. Brown JL, Peach MS, Nair LS, Kumbar SG, Laurencin CT. Composite scaffolds: bridging nanofiber and microsphere architectures to improve bioactivity of mechanically competent constructs. J Biomed Mater Res A. 2010 Dec 15; 95(4):1150-8. PMID: 20878987.
      View in: PubMed
    44. Deng M, Nair LS, Nukavarapu SP, Kumbar SG, Jiang T, Weikel AL, Krogman NR, Allcock HR, Laurencin CT. In Situ Porous Structures: A Unique Polymer Erosion Mechanism in Biodegradable Dipeptide-based Polyphosphazene and Polyester Blends Producing Matrices for Regenerative Engineering. Adv Funct Mater. 2010 Sep 9; 20(17):2743-2957. PMID: 21789036.
      View in: PubMed
    45. Weikel AL, Owens SG, Morozowich NL, Deng M, Nair LS, Laurencin CT, Allcock HR. Miscibility of choline-substituted polyphosphazenes with PLGA and osteoblast activity on resulting blends. Biomaterials. 2010 Nov; 31(33):8507-15. PMID: 20800277.
      View in: PubMed
    46. Cushnie EK, Khan YM, Laurencin CT. Tissue-engineered matrices as functional delivery systems: adsorption and release of bioactive proteins from degradable composite scaffolds. J Biomed Mater Res A. 2010 Aug; 94(2):568-75. PMID: 20198692.
      View in: PubMed
    47. Sethuraman S, Nair LS, El-Amin S, Nguyen MT, Singh A, Greish YE, Allcock HR, Brown PW, Laurencin CT. Development and characterization of biodegradable nanocomposite injectables for orthopaedic applications based on polyphosphazenes. J Biomater Sci Polym Ed. 2011; 22(4-6):733-52. PMID: 20566055.
      View in: PubMed
    48. Jiang T, Khan Y, Nair LS, Abdel-Fattah WI, Laurencin CT. Functionalization of chitosan/poly(lactic acid-glycolic acid) sintered microsphere scaffolds via surface heparinization for bone tissue engineering. J Biomed Mater Res A. 2010 Jun 1; 93(3):1193-208. PMID: 19777575.
      View in: PubMed
    49. Wang J, Valmikinathan CM, Liu W, Laurencin CT, Yu X. Spiral-structured, nanofibrous, 3D scaffolds for bone tissue engineering. J Biomed Mater Res A. 2010 May; 93(2):753-62. PMID: 19642211.
      View in: PubMed
    50. Deng M, Nair LS, Nukavarapu SP, Jiang T, Kanner WA, Li X, Kumbar SG, Weikel AL, Krogman NR, Allcock HR, Laurencin CT. Dipeptide-based polyphosphazene and polyester blends for bone tissue engineering. Biomaterials. 2010 Jun; 31(18):4898-908. PMID: 20334909; PMCID: PMC2856749.
    51. Jiang T, Nukavarapu SP, Deng M, Jabbarzadeh E, Kofron MD, Doty SB, Abdel-Fattah WI, Laurencin CT. Chitosan-poly(lactide-co-glycolide) microsphere-based scaffolds for bone tissue engineering: in vitro degradation and in vivo bone regeneration studies. Acta Biomater. 2010 Sep; 6(9):3457-70. PMID: 20307694.
      View in: PubMed
    52. Feng G, Yang X, Shang H, Marks IW, Shen FH, Katz A, Arlet V, Laurencin CT, Li X. Multipotential differentiation of human anulus fibrosus cells: an in vitro study. J Bone Joint Surg Am. 2010 Mar; 92(3):675-85. PMID: 20194326.
      View in: PubMed
    53. Deng M, Nair LS, Nukavarapu SP, Kumbar SG, Brown JL, Krogman NR, Weikel AL, Allcock HR, Laurencin CT. Biomimetic, bioactive etheric polyphosphazene-poly(lactide-co-glycolide) blends for bone tissue engineering. J Biomed Mater Res A. 2010 Jan; 92(1):114-25. PMID: 19165780.
      View in: PubMed
    54. Sethuraman S, Nair LS, El-Amin S, Nguyen MT, Singh A, Krogman N, Greish YE, Allcock HR, Brown PW, Laurencin CT. Mechanical properties and osteocompatibility of novel biodegradable alanine based polyphosphazenes: Side group effects. Acta Biomater. 2010 Jun; 6(6):1931-7. PMID: 20004751; PMCID: PMC2862891.
    55. Butler DL, Goldstein SA, Guldberg RE, Guo XE, Kamm R, Laurencin CT, McIntire LV, Mow VC, Nerem RM, Sah RL, Soslowsky LJ, Spilker RL, Tranquillo RT. The impact of biomechanics in tissue engineering and regenerative medicine. Tissue Eng Part B Rev. 2009 Dec; 15(4):477-84. PMID: 19583462; PMCID: PMC3192183.
    56. Lv Q, Nair L, Laurencin CT. Fabrication, characterization, and in vitro evaluation of poly(lactic acid glycolic acid)/nano-hydroxyapatite composite microsphere-based scaffolds for bone tissue engineering in rotating bioreactors. J Biomed Mater Res A. 2009 Dec; 91(3):679-91. PMID: 19030184.
      View in: PubMed
    57. Oredein-McCoy O, Krogman NR, Weikel AL, Hindenlang MD, Allcock HR, Laurencin CT. Novel factor-loaded polyphosphazene matrices: potential for driving angiogenesis. J Microencapsul. 2009 Sep; 26(6):544-55. PMID: 18972247; PMCID: PMC2755246.
    58. Merrell JG, McLaughlin SW, Tie L, Laurencin CT, Chen AF, Nair LS. Curcumin-loaded poly(epsilon-caprolactone) nanofibres: diabetic wound dressing with anti-oxidant and anti-inflammatory properties. Clin Exp Pharmacol Physiol. 2009 Dec; 36(12):1149-56. PMID: 19473187; PMCID: PMC2796710.
    59. Krogman NR, Weikel AL, Kristhart KA, Nukavarapu SP, Deng M, Nair LS, Laurencin CT, Allcock HR. The influence of side group modification in polyphosphazenes on hydrolysis and cell adhesion of blends with PLGA. Biomaterials. 2009 Jun; 30(17):3035-41. PMID: 19345410; PMCID: PMC2693372.
    60. Bhattacharyya S, Kumbar SG, Khan YM, Nair LS, Singh A, Krogman NR, Brown PW, Allcock HR, Laurencin CT. Biodegradable polyphosphazene-nanohydroxyapatite composite nanofibers: scaffolds for bone tissue engineering. J Biomed Nanotechnol. 2009 Feb; 5(1):69-75. PMID: 20055108.
      View in: PubMed
    61. Laurencin CT, Kumbar SG, Nukavarapu SP. Nanotechnology and orthopedics: a personal perspective. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Jan-Feb; 1(1):6-10. PMID: 20049774.
      View in: PubMed
    62. Freeman JW, Woods MD, Cromer DA, Wright LD, Laurencin CT. Tissue engineering of the anterior cruciate ligament: the viscoelastic behavior and cell viability of a novel braid-twist scaffold. J Biomater Sci Polym Ed. 2009; 20(12):1709-28. PMID: 19723437.
      View in: PubMed
    63. Taylor ED, Khan Y, Laurencin CT. Tissue engineering of bone: a primer for the practicing hand surgeon. J Hand Surg Am. 2009 Jan; 34(1):164-6. PMID: 19121744.
      View in: PubMed
    64. Kumbar SG, James R, Nukavarapu SP, Laurencin CT. Electrospun nanofiber scaffolds: engineering soft tissues. Biomed Mater. 2008 Sep; 3(3):034002. PMID: 18689924.
      View in: PubMed
    65. Jabbarzadeh E, Starnes T, Khan YM, Jiang T, Wirtel AJ, Deng M, Lv Q, Nair LS, Doty SB, Laurencin CT. Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: a combined gene therapy-cell transplantation approach. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11099-104. PMID: 18678895; PMCID: PMC2516212.
    66. Brown JL, Nair LS, Laurencin CT. Solvent/non-solvent sintering: a novel route to create porous microsphere scaffolds for tissue regeneration. J Biomed Mater Res B Appl Biomater. 2008 Aug; 86(2):396-406. PMID: 18161819; PMCID: PMC2755242.
    67. Kumbar SG, Nukavarapu SP, James R, Nair LS, Laurencin CT. Electrospun poly(lactic acid-co-glycolic acid) scaffolds for skin tissue engineering. Biomaterials. 2008 Oct; 29(30):4100-7. PMID: 18639927; PMCID: PMC2605109.
    68. Nukavarapu SP, Kumbar SG, Brown JL, Krogman NR, Weikel AL, Hindenlang MD, Nair LS, Allcock HR, Laurencin CT. Polyphosphazene/nano-hydroxyapatite composite microsphere scaffolds for bone tissue engineering. Biomacromolecules. 2008 Jul; 9(7):1818-25. PMID: 18517248; PMCID: PMC2746952.
    69. Laurencin CT, Nair L. The FDA and safety--beyond the heparin crisis. Nat Biotechnol. 2008 Jun; 26(6):621-3. PMID: 18536680.
      View in: PubMed
    70. Feng G, Wan Y, Balian G, Laurencin CT, Li X. Adenovirus-mediated expression of growth and differentiation factor-5 promotes chondrogenesis of adipose stem cells. Growth Factors. 2008 Jun; 26(3):132-42. PMID: 18569021; PMCID: PMC3034080.
    71. Touny AH, Laurencin C, Nair L, Allcock H, Brown PW. Formation of composites comprised of calcium deficient HAp and cross-linked gelatin. J Mater Sci Mater Med. 2008 Oct; 19(10):3193-201. PMID: 18452028.
      View in: PubMed
    72. Greish YE, Sturgeon JL, Singh A, Krogman NR, Touny AH, Sethuraman S, Nair LS, Laurencin CT, Allcock HR, Brown PW. Formation and properties of composites comprised of calcium-deficient hydroxyapatites and ethyl alanate polyphosphazenes. J Mater Sci Mater Med. 2008 Sep; 19(9):3153-60. PMID: 18437537.
      View in: PubMed
    73. Nair LS, Laurencin CT. Nanofibers and nanoparticles for orthopaedic surgery applications. J Bone Joint Surg Am. 2008 Feb; 90 Suppl 1:128-31. PMID: 18292367.
      View in: PubMed
    74. Khan Y, Yaszemski MJ, Mikos AG, Laurencin CT. Tissue engineering of bone: material and matrix considerations. J Bone Joint Surg Am. 2008 Feb; 90 Suppl 1:36-42. PMID: 18292355.
      View in: PubMed
    75. Khan Y, Laurencin CT. Fracture repair with ultrasound: clinical and cell-based evaluation. J Bone Joint Surg Am. 2008 Feb; 90 Suppl 1:138-44. PMID: 18292369.
      View in: PubMed
    76. Einhorn TA, Laurencin CT, Lyons K. An AAOS-NIH symposium. Fracture repair: challenges, opportunities, and directions for future research. J Bone Joint Surg Am. 2008 Feb; 90(2):438-42. PMID: 18245605.
      View in: PubMed
    77. Laurencin CT, Einhorn TA, Lyons K. Fracture repair: challenges and opportunities. J Bone Joint Surg Am. 2008 Feb; 90 Suppl 1:1-2. PMID: 18292348.
      View in: PubMed
    78. Jiang T, Kumbar SG, Nair LS, Laurencin CT. Biologically active chitosan systems for tissue engineering and regenerative medicine. Curr Top Med Chem. 2008; 8(4):354-64. PMID: 18393897.
      View in: PubMed
    79. Laurencin CT, El-Amin SF. Xenotransplantation in orthopaedic surgery. J Am Acad Orthop Surg. 2008 Jan; 16(1):4-8. PMID: 18180387.
      View in: PubMed
    80. Laurencin CT, Christensen DM, Taylor ED. HIV/AIDS and the African-American community: a state of emergency. J Natl Med Assoc. 2008 Jan; 100(1):35-43. PMID: 18277806.
      View in: PubMed
    81. Cushnie EK, Khan YM, Laurencin CT. Amorphous hydroxyapatite-sintered polymeric scaffolds for bone tissue regeneration: physical characterization studies. J Biomed Mater Res A. 2008 Jan; 84(1):54-62. PMID: 17600320.
      View in: PubMed
    82. Jabbarzadeh E, Jiang T, Deng M, Nair LS, Khan YM, Laurencin CT. Human endothelial cell growth and phenotypic expression on three dimensional poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering. Biotechnol Bioeng. 2007 Dec 1; 98(5):1094-102. PMID: 17497742.
      View in: PubMed
    83. Wan Y, Feng G, Shen FH, Laurencin CT, Li X. Biphasic scaffold for annulus fibrosus tissue regeneration. Biomaterials. 2008 Feb; 29(6):643-52. PMID: 17997480.
      View in: PubMed
    84. Wan Y, Feng G, Shen FH, Balian G, Laurencin CT, Li X. Novel biodegradable poly(1,8-octanediol malate) for annulus fibrosus regeneration. Macromol Biosci. 2007 Nov 12; 7(11):1217-24. PMID: 17683110.
      View in: PubMed
    85. Nair LS, Starnes T, Ko JW, Laurencin CT. Development of injectable thermogelling chitosan-inorganic phosphate solutions for biomedical applications. Biomacromolecules. 2007 Dec; 8(12):3779-85. PMID: 17994699.
      View in: PubMed
    86. Laurencin CT. Cato T. Laurencin, MD, PhD. J Natl Med Assoc. 2007 Nov; 99(11):1286-7. PMID: 18020107; PMCID: PMC2574318.
    87. Deng M, Nair LS, Nukavarapu SP, Kumbar SG, Jiang T, Krogman NR, Singh A, Allcock HR, Laurencin CT. Miscibility and in vitro osteocompatibility of biodegradable blends of poly[(ethyl alanato) (p-phenyl phenoxy) phosphazene] and poly(lactic acid-glycolic acid). Biomaterials. 2008 Jan; 29(3):337-49. PMID: 17942150; PMCID: PMC2129129.
    88. Sethuraman S, Nair LS, El-Amin S, Nguyen MT, Greish YE, Bender JD, Brown PW, Allcock HR, Laurencin CT. Novel low temperature setting nanocrystalline calcium phosphate cements for bone repair: osteoblast cellular response and gene expression studies. J Biomed Mater Res A. 2007 Sep 15; 82(4):884-91. PMID: 17335035.
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    89. Kofron MD, Cooper JA, Kumbar SG, Laurencin CT. Novel tubular composite matrix for bone repair. J Biomed Mater Res A. 2007 Aug; 82(2):415-25. PMID: 17295242.
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    90. Cui M, Wan Y, Anderson DG, Shen FH, Leo BM, Laurencin CT, Balian G, Li X. Mouse growth and differentiation factor-5 protein and DNA therapy potentiates intervertebral disc cell aggregation and chondrogenic gene expression. Spine J. 2008 Mar-Apr; 8(2):287-95. PMID: 17974491.
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    91. Kumbar SG, Bhattacharyya S, Sethuraman S, Laurencin CT. A preliminary report on a novel electrospray technique for nanoparticle based biomedical implants coating: precision electrospraying. J Biomed Mater Res B Appl Biomater. 2007 Apr; 81(1):91-103. PMID: 16924613.
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    92. Krogman NR, Singh A, Nair LS, Laurencin CT, Allcock HR. Miscibility of bioerodible polyphosphazene/poly(lactide-co-glycolide) blends. Biomacromolecules. 2007 Apr; 8(4):1306-12. PMID: 17338563.
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    93. Abdel-Fattah WI, Jiang T, El-Bassyouni Gel-T, Laurencin CT. Synthesis, characterization of chitosans and fabrication of sintered chitosan microsphere matrices for bone tissue engineering. Acta Biomater. 2007 Jul; 3(4):503-14. PMID: 17320493.
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    94. Cooper JA, Sahota JS, Gorum WJ, Carter J, Doty SB, Laurencin CT. Biomimetic tissue-engineered anterior cruciate ligament replacement. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3049-54. PMID: 17360607; PMCID: PMC1805619.
    95. Christenson EM, Anseth KS, van den Beucken JJ, Chan CK, Ercan B, Jansen JA, Laurencin CT, Li WJ, Murugan R, Nair LS, Ramakrishna S, Tuan RS, Webster TJ, Mikos AG. Nanobiomaterial applications in orthopedics. J Orthop Res. 2007 Jan; 25(1):11-22. PMID: 17048259.
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    96. Jabbarzadeh E, Nair LS, Khan YM, Deng M, Laurencin CT. Apatite nano-crystalline surface modification of poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering: implications for protein adsorption. J Biomater Sci Polym Ed. 2007; 18(9):1141-52. PMID: 17931504.
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    97. Freeman JW, Woods MD, Laurencin CT. Tissue engineering of the anterior cruciate ligament using a braid-twist scaffold design. J Biomech. 2007; 40(9):2029-36. PMID: 17097666; PMCID: PMC2034317.
    98. Shen FH, Zeng Q, Lv Q, Choi L, Balian G, Li X, Laurencin CT. Osteogenic differentiation of adipose-derived stromal cells treated with GDF-5 cultured on a novel three-dimensional sintered microsphere matrix. Spine J. 2006 Nov-Dec; 6(6):615-23. PMID: 17088192.
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    99. Kumbar SG, Nair LS, Bhattacharyya S, Laurencin CT. Polymeric nanofibers as novel carriers for the delivery of therapeutic molecules. J Nanosci Nanotechnol. 2006 Sep-Oct; 6(9-10):2591-607. PMID: 17048469.
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    100. Dupree MA, Pollack SR, Levine EM, Laurencin CT. Fibroblast growth factor 2 induced proliferation in osteoblasts and bone marrow stromal cells: a whole cell model. Biophys J. 2006 Oct 15; 91(8):3097-112. PMID: 16861274; PMCID: PMC1578487.
    101. Kofron MD, Laurencin CT. Bone tissue engineering by gene delivery. Adv Drug Deliv Rev. 2006 Jul 7; 58(4):555-76. PMID: 16790291.
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    102. Sethuraman S, Nair LS, El-Amin S, Farrar R, Nguyen MT, Singh A, Allcock HR, Greish YE, Brown PW, Laurencin CT. In vivo biodegradability and biocompatibility evaluation of novel alanine ester based polyphosphazenes in a rat model. J Biomed Mater Res A. 2006 Jun 15; 77(4):679-87. PMID: 16514601.
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    103. Jiang T, Abdel-Fattah WI, Laurencin CT. In vitro evaluation of chitosan/poly(lactic acid-glycolic acid) sintered microsphere scaffolds for bone tissue engineering. Biomaterials. 2006 Oct; 27(28):4894-903. PMID: 16762408.
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    104. Laurencin CT, Khan Y, Kofron M, El-Amin S, Botchwey E, Yu X, Cooper JA. The ABJS Nicolas Andry Award: Tissue engineering of bone and ligament: a 15-year perspective. Clin Orthop Relat Res. 2006 Jun; 447:221-36. PMID: 16741478.
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    105. Greish YE, Bender JD, Lakshmi S, Brown PW, Allcock HR, Laurencin CT. Formation of hydroxyapatite-polyphosphazene polymer composites at physiologic temperature. J Biomed Mater Res A. 2006 May; 77(2):416-25. PMID: 16482546.
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    106. Pelled G, Tai K, Sheyn D, Zilberman Y, Kumbar S, Nair LS, Laurencin CT, Gazit D, Ortiz C. Structural and nanoindentation studies of stem cell-based tissue-engineered bone. J Biomech. 2007; 40(2):399-411. PMID: 16524583.
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    107. El-Amin SF, Botchwey E, Tuli R, Kofron MD, Mesfin A, Sethuraman S, Tuan RS, Laurencin CT. Human osteoblast cells: isolation, characterization, and growth on polymers for musculoskeletal tissue engineering. J Biomed Mater Res A. 2006 Mar 1; 76(3):439-49. PMID: 16541483.
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    108. Singh A, Krogman NR, Sethuraman S, Nair LS, Sturgeon JL, Brown PW, Laurencin CT, Allcock HR. Effect of side group chemistry on the properties of biodegradable L-alanine cosubstituted polyphosphazenes. Biomacromolecules. 2006 Mar; 7(3):914-8. PMID: 16529431.
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    109. Cooper JA, Bailey LO, Carter JN, Castiglioni CE, Kofron MD, Ko FK, Laurencin CT. Evaluation of the anterior cruciate ligament, medial collateral ligament, achilles tendon and patellar tendon as cell sources for tissue-engineered ligament. Biomaterials. 2006 May; 27(13):2747-54. PMID: 16414115.
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    110. Khan Y, El-Amin SF, Laurencin C. In vitro and in vivo evaluation of a novel polymer-ceramic composite scaffold for bone tissue engineering. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:529-30. PMID: 17946840.
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    111. Laurencin C, Khan Y, El-Amin SF. Bone graft substitutes. Expert Rev Med Devices. 2006 Jan; 3(1):49-57. PMID: 16359252.
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    112. Nair LS, Laurencin CT. Polymers as biomaterials for tissue engineering and controlled drug delivery. Adv Biochem Eng Biotechnol. 2006; 102:47-90. PMID: 17089786.
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    113. Nair LS, Lee DA, Bender JD, Barrett EW, Greish YE, Brown PW, Allcock HR, Laurencin CT. Synthesis, characterization, and osteocompatibility evaluation of novel alanine-based polyphosphazenes. J Biomed Mater Res A. 2006 Jan; 76(1):206-13. PMID: 16265637.
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    114. Li X, Jin L, Balian G, Laurencin CT, Greg Anderson D. Demineralized bone matrix gelatin as scaffold for osteochondral tissue engineering. Biomaterials. 2006 Apr; 27(11):2426-33. PMID: 16343611.
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    115. Laurencin CT, Freeman JW. Ligament tissue engineering: an evolutionary materials science approach. Biomaterials. 2005 Dec; 26(36):7530-6. PMID: 16045982.
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    116. Greish YE, Bender JD, Lakshmi S, Brown PW, Allcock HR, Laurencin CT. Composite formation from hydroxyapatite with sodium and potassium salts of polyphosphazene. J Mater Sci Mater Med. 2005 Jul; 16(7):613-20. PMID: 15965592.
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    117. Cooper JA, Lu HH, Ko FK, Freeman JW, Laurencin CT. Fiber-based tissue-engineered scaffold for ligament replacement: design considerations and in vitro evaluation. Biomaterials. 2005 May; 26(13):1523-32. PMID: 15522754.
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    118. Kofron MD, Laurencin CT. Orthopaedic applications of gene therapy. Curr Gene Ther. 2005 Feb; 5(1):37-61. PMID: 15638710.
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    119. Lu HH, Cooper JA, Manuel S, Freeman JW, Attawia MA, Ko FK, Laurencin CT. Anterior cruciate ligament regeneration using braided biodegradable scaffolds: in vitro optimization studies. Biomaterials. 2005 Aug; 26(23):4805-16. PMID: 15763260.
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    120. Greish YE, Bender JD, Lakshmi S, Brown PW, Allcock HR, Laurencin CT. Low temperature formation of hydroxyapatite-poly(alkyl oxybenzoate)phosphazene composites for biomedical applications. Biomaterials. 2005 Jan; 26(1):1-9. PMID: 15193876.
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    121. Borden M, Attawia M, Khan Y, El-Amin SF, Laurencin CT. Tissue-engineered bone formation in vivo using a novel sintered polymeric microsphere matrix. J Bone Joint Surg Br. 2004 Nov; 86(8):1200-8. PMID: 15568538.
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    122. Nair LS, Bhattacharyya S, Bender JD, Greish YE, Brown PW, Allcock HR, Laurencin CT. Fabrication and optimization of methylphenoxy substituted polyphosphazene nanofibers for biomedical applications. Biomacromolecules. 2004 Nov-Dec; 5(6):2212-20. PMID: 15530035.
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    123. Kofron MD, Li X, Laurencin CT. Protein- and gene-based tissue engineering in bone repair. Curr Opin Biotechnol. 2004 Oct; 15(5):399-405. PMID: 15464368.
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    124. El-Amin SF, Kofron MD, Attawia MA, Lu HH, Tuan RS, Laurencin CT. Molecular regulation of osteoblasts for tissue engineered bone repair. Clin Orthop Relat Res. 2004 Oct; (427):220-5. PMID: 15552161.
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    125. Katti DS, Robinson KW, Ko FK, Laurencin CT. Bioresorbable nanofiber-based systems for wound healing and drug delivery: optimization of fabrication parameters. J Biomed Mater Res B Appl Biomater. 2004 Aug 15; 70(2):286-96. PMID: 15264311.
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    126. Yu X, Botchwey EA, Levine EM, Pollack SR, Laurencin CT. Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization. Proc Natl Acad Sci U S A. 2004 Aug 3; 101(31):11203-8. PMID: 15277663; PMCID: PMC509184.
    127. Khan YM, Katti DS, Laurencin CT. Novel polymer-synthesized ceramic composite-based system for bone repair: an in vitro evaluation. J Biomed Mater Res A. 2004 Jun 15; 69(4):728-37. PMID: 15162415.
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    128. Kofron MD, Laurencin CT. Development of a calcium phosphate co-precipitate/poly(lactide-co-glycolide) DNA delivery system: release kinetics and cellular transfection studies. Biomaterials. 2004 Jun; 25(13):2637-43. PMID: 14751750.
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    129. Botchwey EA, Pollack SR, Levine EM, Johnston ED, Laurencin CT. Quantitative analysis of three-dimensional fluid flow in rotating bioreactors for tissue engineering. J Biomed Mater Res A. 2004 May 1; 69(2):205-15. PMID: 15057993.
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    130. Nair LS, Bhattacharyya S, Laurencin CT. Development of novel tissue engineering scaffolds via electrospinning. Expert Opin Biol Ther. 2004 May; 4(5):659-68. PMID: 15155157.
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    131. Kofron MD, Opsitnick NC, Attawia MA, Laurencin CT. Cryopreservation of tissue engineered constructs for bone. J Orthop Res. 2003 Nov; 21(6):1005-10. PMID: 14554212.
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    132. Botchwey EA, Dupree MA, Pollack SR, Levine EM, Laurencin CT. Tissue engineered bone: measurement of nutrient transport in three-dimensional matrices. J Biomed Mater Res A. 2003 Oct 1; 67(1):357-67. PMID: 14517896.
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    133. Laurencin CT, Katti DS. Repair and restore with tissue engineering. IEEE Eng Med Biol Mag. 2003 Sep-Oct; 22(5):16-7. PMID: 14699931.
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    134. Ambrosio AM, Sahota JS, Runge C, Kurtz SM, Lakshmi S, Allcock HR, Laurencin CT. Novel polyphosphazene-hydroxyapatite composites as biomaterials. IEEE Eng Med Biol Mag. 2003 Sep-Oct; 22(5):18-26. PMID: 14699932.
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    135. Kofron MD, Zhang JX, Lieberman JR, Laurencin CT. Genetically modified mesodermal-derived cells for bone tissue engineering. IEEE Eng Med Biol Mag. 2003 Sep-Oct; 22(5):57-64. PMID: 14699937.
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    136. Lu HH, Kofron MD, El-Amin SF, Attawia MA, Laurencin CT. In vitro bone formation using muscle-derived cells: a new paradigm for bone tissue engineering using polymer-bone morphogenetic protein matrices. Biochem Biophys Res Commun. 2003 Jun 13; 305(4):882-9. PMID: 12767913.
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    137. Lakshmi S, Katti DS, Laurencin CT. Biodegradable polyphosphazenes for drug delivery applications. Adv Drug Deliv Rev. 2003 Apr 25; 55(4):467-82. PMID: 12706046.
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    138. El-Amin SF, Lu HH, Khan Y, Burems J, Mitchell J, Tuan RS, Laurencin CT. Extracellular matrix production by human osteoblasts cultured on biodegradable polymers applicable for tissue engineering. Biomaterials. 2003 Mar; 24(7):1213-21. PMID: 12527262.
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    139. Lu HH, El-Amin SF, Scott KD, Laurencin CT. Three-dimensional, bioactive, biodegradable, polymer-bioactive glass composite scaffolds with improved mechanical properties support collagen synthesis and mineralization of human osteoblast-like cells in vitro. J Biomed Mater Res A. 2003 Mar 1; 64(3):465-74. PMID: 12579560.
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    140. Borden M, El-Amin SF, Attawia M, Laurencin CT. Structural and human cellular assessment of a novel microsphere-based tissue engineered scaffold for bone repair. Biomaterials. 2003 Feb; 24(4):597-609. PMID: 12437954.
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    141. Botchwey EA, Pollack SR, El-Amin S, Levine EM, Tuan RS, Laurencin CT. Human osteoblast-like cells in three-dimensional culture with fluid flow. Biorheology. 2003; 40(1-3):299-306. PMID: 12454419.
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    142. Katti DS, Lakshmi S, Langer R, Laurencin CT. Toxicity, biodegradation and elimination of polyanhydrides. Adv Drug Deliv Rev. 2002 Oct 16; 54(7):933-61. PMID: 12384316.
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    143. Borden M, Attawia M, Laurencin CT. The sintered microsphere matrix for bone tissue engineering: in vitro osteoconductivity studies. J Biomed Mater Res. 2002 Sep 5; 61(3):421-9. PMID: 12115467.
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    144. Li WJ, Laurencin CT, Caterson EJ, Tuan RS, Ko FK. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res. 2002 Jun 15; 60(4):613-21. PMID: 11948520.
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    145. Ambrosio AM, Allcock HR, Katti DS, Laurencin CT. Degradable polyphosphazene/poly(alpha-hydroxyester) blends: degradation studies. Biomaterials. 2002 Apr; 23(7):1667-72. PMID: 11924588.
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    146. Borden M, Attawia M, Khan Y, Laurencin CT. Tissue engineered microsphere-based matrices for bone repair: design and evaluation. Biomaterials. 2002 Jan; 23(2):551-9. PMID: 11761175.
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    147. El-Amin SF, Attawia M, Lu HH, Shah AK, Chang R, Hickok NJ, Tuan RS, Laurencin CT. Integrin expression by human osteoblasts cultured on degradable polymeric materials applicable for tissue engineered bone. J Orthop Res. 2002 Jan; 20(1):20-8. PMID: 11853086.
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    148. Laurencin CT, Attawia MA, Lu LQ, Borden MD, Lu HH, Gorum WJ, Lieberman JR. Poly(lactide-co-glycolide)/hydroxyapatite delivery of BMP-2-producing cells: a regional gene therapy approach to bone regeneration. Biomaterials. 2001 Jun; 22(11):1271-7. PMID: 11336299.
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    149. Botchwey EA, Pollack SR, Levine EM, Laurencin CT. Bone tissue engineering in a rotating bioreactor using a microcarrier matrix system. J Biomed Mater Res. 2001 May; 55(2):242-53. PMID: 11255176; PMCID: PMC3464017.
    150. Ambrosio AM, Sahota JS, Khan Y, Laurencin CT. A novel amorphous calcium phosphate polymer ceramic for bone repair: I. Synthesis and characterization. J Biomed Mater Res. 2001 May 1; 58(3):295-301. PMID: 11319744.
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    151. Attawia MA, Borden MD, Herbert KM, Katti DS, Asrari F, Uhrich KE, Laurencin CT. Regional drug delivery with radiation for the treatment of Ewing's sarcoma. In vitro development of a taxol release system. J Control Release. 2001 Apr 2; 71(2):193-202. PMID: 11274751.
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    152. Greenwald AS, Boden SD, Goldberg VM, Khan Y, Laurencin CT, Rosier RN. Bone-graft substitutes: facts, fictions, and applications. J Bone Joint Surg Am. 2001; 83-A Suppl 2 Pt 2:98-103. PMID: 11712842.
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    153. Attawia MA, Nicholson JJ, Laurencin CT. Coculture system to assess biocompatibility of candidate orthopaedic materials. Clin Orthop Relat Res. 1999 Aug; (365):230-6. PMID: 10627707.
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    154. Laurencin CT. Quality and fairness: achieving the paradigm. A personal perspective. Clin Orthop Relat Res. 1999 May; (362):55-7. PMID: 10335279.
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    155. Laurencin CT, Ambrosio AM, Borden MD, Cooper JA. Tissue engineering: orthopedic applications. Annu Rev Biomed Eng. 1999; 1:19-46. PMID: 11701481.
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    156. Laurencin CT, Lipson SJ, Senatus P, Botchwey E, Jones TR, Koris M, Hunter J. The stenosis ratio: a new tool for the diagnosis of degenerative spinal stenosis. Int J Surg Investig. 1999; 1(2):127-31. PMID: 11341632.
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    157. Attawia MA, Herbert KM, Uhrich KE, Langer R, Laurencin CT. Proliferation, morphology, and protein expression by osteoblasts cultured on poly(anhydride-co-imides). J Biomed Mater Res. 1999; 48(3):322-7. PMID: 10398037.
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    158. Laurencin CT, Cummings RS, Jones TR, Martin L. Fracture-dislocation of the lunotriquetral coalition. J Natl Med Assoc. 1998 Dec; 90(12):779-81. PMID: 9884499; PMCID: PMC2608435.
    159. Uhrich KE, Ibim SE, Larrier DR, Langer R, Laurencin CT. Chemical changes during in vivo degradation of poly(anhydride-imide) matrices. Biomaterials. 1998 Nov; 19(22):2045-50. PMID: 9870755.
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    160. Ibim SM, Uhrich KE, Bronson R, El-Amin SF, Langer RS, Laurencin CT. Poly(anhydride-co-imides): in vivo biocompatibility in a rat model. Biomaterials. 1998 May; 19(10):941-51. PMID: 9690836.
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    161. Laurencin C, Attawia M, Botchwey E, Warren R, Attia E. Cell-material systems for anterior cruciate ligament regeneration. In Vitro Cell Dev Biol Anim. 1998 Feb; 34(2):90-2. PMID: 9542643.
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    162. Ibim SM, el-Amin SF, Goad ME, Ambrosio AM, Allcock HR, Laurencin CT. In vitro release of colchicine using poly(phosphazenes): the development of delivery systems for musculoskeletal use. Pharm Dev Technol. 1998 Feb; 3(1):55-62. PMID: 9532600.
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    163. Ibim SE, Uhrich KE, Attawia M, Shastri VR, El-Amin SF, Bronson R, Langer R, Laurencin CT. Preliminary in vivo report on the osteocompatibility of poly(anhydride-co-imides) evaluated in a tibial model. J Biomed Mater Res. 1998; 43(4):374-9. PMID: 9855196.
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    164. Ibim SE, Ambrosio AM, Kwon MS, El-Amin SF, Allcock HR, Laurencin CT. Novel polyphosphazene/poly(lactide-co-glycolide) blends: miscibility and degradation studies. Biomaterials. 1997 Dec; 18(23):1565-9. PMID: 9430340.
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    165. Williams RJ, Laurencin CT, Warren RF, Speciale AC, Brause BD, O'Brien S. Septic arthritis after arthroscopic anterior cruciate ligament reconstruction. Diagnosis and management. Am J Sports Med. 1997 Mar-Apr; 25(2):261-7. PMID: 9079185.
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    166. Laurencin CT, Stephens S, Warren RF, Altchek DW. Arthroscopic Bankart repair using a degradable tack. A followup study using optimized indications. Clin Orthop Relat Res. 1996 Nov; (332):132-7. PMID: 8913155.
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    167. Laurencin CT, Attawia MA, Elgendy HE, Herbert KM. Tissue engineered bone-regeneration using degradable polymers: the formation of mineralized matrices. Bone. 1996 Jul; 19(1 Suppl):93S-99S. PMID: 8831000.
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    168. Laurencin CT, Ferriter PJ, Millis MB. Oblique proximal tibial osteotomy for the correction of tibia vara in the young. Clin Orthop Relat Res. 1996 Jun; (327):218-24. PMID: 8641067.
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    169. Attawia MA, Uhrich KE, Botchwey E, Langer R, Laurencin CT. In vitro bone biocompatibility of poly (anhydride-co-imides) containing pyromellitylimidoalanine. J Orthop Res. 1996 May; 14(3):445-54. PMID: 8676258.
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    170. Laurencin CT, El-Amin SF, Ibim SE, Willoughby DA, Attawia M, Allcock HR, Ambrosio AA. A highly porous 3-dimensional polyphosphazene polymer matrix for skeletal tissue regeneration. J Biomed Mater Res. 1996 Feb; 30(2):133-8. PMID: 9019476.
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    171. Devin JE, Attawia MA, Laurencin CT. Three-dimensional degradable porous polymer-ceramic matrices for use in bone repair. J Biomater Sci Polym Ed. 1996; 7(8):661-9. PMID: 8639475.
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    172. Attawia MA, Uhrich KE, Botchwey E, Fan M, Langer R, Laurencin CT. Cytotoxicity testing of poly(anhydride-co-imides) for orthopedic applications. J Biomed Mater Res. 1995 Oct; 29(10):1233-40. PMID: 8557725.
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    173. Attawia MA, Herbert KM, Laurencin CT. Osteoblast-like cell adherance and migration through 3-dimensional porous polymer matrices. Biochem Biophys Res Commun. 1995 Aug 15; 213(2):639-44. PMID: 7646521.
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    174. Attawia MA, Devin JE, Laurencin CT. Immunofluorescence and confocal laser scanning microscopy studies of osteoblast growth and phenotypic expression in three-dimensional degradable synthetic matrices. J Biomed Mater Res. 1995 Jul; 29(7):843-8. PMID: 7593023.
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    175. Hinton JL, Warejcka DJ, Mei Y, McLendon RE, Laurencin C, Lucas PA, Robinson JS. Inhibition of epidural scar formation after lumbar laminectomy in the rat. Spine (Phila Pa 1976). 1995 Mar 1; 20(5):564-70; discussion 579-80. PMID: 7604326.
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    176. Laurencin CT, Schwartz JT, Koris MJ. Compression of the ulnar nerve at the elbow in association with synovial cysts. Orthop Rev. 1994 Jan; 23(1):62-5. PMID: 8159454.
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    177. Norman ME, Elgendy HM, Shors EC, el-Amin SF, Laurencin CT. An in-vitro evaluation of coralline porous hydroxyapatite as a scaffold for osteoblast growth. Clin Mater. 1994; 17(2):85-91. PMID: 10150211.
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    178. Laurencin CT, Norman ME, Elgendy HM, el-Amin SF, Allcock HR, Pucher SR, Ambrosio AA. Use of polyphosphazenes for skeletal tissue regeneration. J Biomed Mater Res. 1993 Jul; 27(7):963-73. PMID: 8360223.
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    179. Laurencin CT, Gerhart T, Witschger P, Satcher R, Domb A, Rosenberg AE, Hanff P, Edsberg L, Hayes W, Langer R. Bioerodible polyanhydrides for antibiotic drug delivery: in vivo osteomyelitis treatment in a rat model system. J Orthop Res. 1993 Mar; 11(2):256-62. PMID: 8483038.
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    180. Laurencin CT, Senatus P, Patti J, Goodman M. Dislocation of the sternoclavicular joint. Evaluation using paraxial computed tomographic reconstruction. Orthop Rev. 1993 Jan; 22(1):101-3. PMID: 8421627.
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    181. Elgendy HM, Norman ME, Keaton AR, Laurencin CT. Osteoblast-like cell (MC3T3-E1) proliferation on bioerodible polymers: an approach towards the development of a bone-bioerodible polymer composite material. Biomaterials. 1993; 14(4):263-9. PMID: 8386557.
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    182. Laurencin CT, Zelicof SB, Scott RD, Ewald FC. Unicompartmental versus total knee arthroplasty in the same patient. A comparative study. Clin Orthop Relat Res. 1991 Dec; (273):151-6. PMID: 1959264.
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    183. Schwartz JT, Waters PM, Laurencin CT. Sciatic-nerve palsy associated with a retained plastic shot container in a shotgun injury. A case report. J Bone Joint Surg Am. 1991 Apr; 73(4):607-9. PMID: 2013601.
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    184. Laurencin C, Domb A, Morris C, Brown V, Chasin M, McConnell R, Lange N, Langer R. Poly(anhydride) administration in high doses in vivo: studies of biocompatibility and toxicology. J Biomed Mater Res. 1990 Nov; 24(11):1463-81. PMID: 2279981.
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    185. Laurencin CT, Pierre-Jacques HM, Langer R. Toxicology and biocompatibility considerations in the evaluation of polymeric materials for biomedical applications. Clin Lab Med. 1990 Sep; 10(3):549-70. PMID: 2253450.
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    186. Lucas PA, Laurencin C, Syftestad GT, Domb A, Goldberg VM, Caplan AI, Langer R. Ectopic induction of cartilage and bone by water-soluble proteins from bovine bone using a polyanhydride delivery vehicle. J Biomed Mater Res. 1990 Jul; 24(7):901-11. PMID: 2398077.
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    187. Laurencin CT, Koh HJ, Neenan TX, Allcock HR, Langer R. Controlled release using a new bioerodible polyphosphazene matrix system. J Biomed Mater Res. 1987 Oct; 21(10):1231-46. PMID: 3693386.
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    188. Laurencin CT, Langer R. Polymeric controlled release systems: new methods for drug delivery. Clin Lab Med. 1987 Jun; 7(2):301-23. PMID: 3301172.
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    189. Ollivierre F, Gubler U, Towle CA, Laurencin C, Treadwell BV. Expression of IL-1 genes in human and bovine chondrocytes: a mechanism for autocrine control of cartilage matrix degradation. Biochem Biophys Res Commun. 1986 Dec 30; 141(3):904-11. PMID: 3028392.
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