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Last Name
Institution

Liisa T Kuhn PhD

TitleAssociate Professor
InstitutionUConn Health Center
DepartmentReconstructive Sciences
AddressMC 1615
MC 1615
263 Farmington Avenue
Phone860-679-3922
Fax860-679-1370
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    Other Positions
    TitleAssistant Professor
    InstitutionUConn Health Center
    DepartmentReconstructive Sciences
    DivisionCenter for Regenerative Medicine and Skeletal Development

    TitleAssistant Professor
    InstitutionUConn Health Center
    DepartmentInstitute for Regenerative Engineering


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Denry I, Kuhn LT. Design and characterization of calcium phosphate ceramic scaffolds for bone tissue engineering. Dent Mater. 2016 Jan; 32(1):43-53. PMID: 26423007.
      View in: PubMed
    2. Woodman JL, Suh MS, Zhang J, Kondaveeti Y, Burgess DJ, White BA, Prestwich GD, Kuhn LT. Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery. Int J Cell Biol. 2015; 2015:249573. PMID: 26448751; PMCID: PMC4581577.
    3. Hurley MM, Gronowicz G, Zhu L, Kuhn LT, Rodner C, Xiao L. Age-Related Changes in FGF-2, Fibroblast Growth Factor Receptors and ß-Catenin Expression in Human Mesenchyme-Derived Progenitor Cells. J Cell Biochem. 2016 Mar; 117(3):721-9. PMID: 26332075.
      View in: PubMed
    4. Wen B, Kuhn L, Charles L, Pendrys D, Shafer D, Freilich M. Comparison of bone morphogenetic protein-2 delivery systems to induce supracrestal bone guided by titanium implants in the rabbit mandible. Clin Oral Implants Res. 2016 Jun; 27(6):676-85. PMID: 26183057.
      View in: PubMed
    5. Gronowicz G, Secor ER, Flynn JR, Jellison ER, Kuhn LT. Therapeutic Touch Has Significant Effects on Mouse Breast Cancer Metastasis and Immune Responses but Not Primary Tumor Size. Evid Based Complement Alternat Med. 2015; 2015:926565. PMID: 26113869; PMCID: PMC4465772.
    6. Charles LF, Woodman JL, Ueno D, Gronowicz G, Hurley MM, Kuhn LT. Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice. Exp Gerontol. 2015 Apr; 64:62-9. PMID: 25681640; PMCID: PMC4388203 [Available on 04/01/16].
    7. Gronowicz G, Hurley MM, Kuhn LT. Optimizing BMP-2-induced bone repair with FGF-2. J Am Acad Orthop Surg. 2014 Oct; 22(10):677-9. PMID: 25281263.
      View in: PubMed
    8. Xin X, Jiang X, Wang L, Stover ML, Zhan S, Huang J, Goldberg AJ, Liu Y, Kuhn L, Reichenberger EJ, Rowe DW, Lichtler AC. A Site-Specific Integrated Col2.3GFP Reporter Identifies Osteoblasts Within Mineralized Tissue Formed In Vivo by Human Embryonic Stem Cells. Stem Cells Transl Med. 2014 Oct; 3(10):1125-37. PMID: 25122686; PMCID: PMC4181390.
    9. Gronowicz G, Kuhn LT. Response to the letter "Age and site should be considered when investigating the effect of growth factors on human bone-derived cells". J Gerontol A Biol Sci Med Sci. 2014 Sep; 69(9):1092-3. PMID: 25056503.
      View in: PubMed
    10. Gomillion CT, Lakhman RK, Kasi RM, Weiss RA, Kuhn LT, Goldberg AJ. Lithium-end-capped polylactide thin films influence osteoblast progenitor cell differentiation and mineralization. J Biomed Mater Res A. 2015 Feb; 103(2):500-10. PMID: 24733780; PMCID: PMC4643685.
    11. Xiao L, Ueno D, Catros S, Homer-Bouthiette C, Charles L, Kuhn L, Hurley MM. Fibroblast growth factor-2 isoform (low molecular weight/18 kDa) overexpression in preosteoblast cells promotes bone regeneration in critical size calvarial defects in male mice. Endocrinology. 2014 Mar; 155(3):965-74. PMID: 24424065; PMCID: PMC3929728.
    12. Kuhn LT, Liu Y, Boyd NL, Dennis JE, Jiang X, Xin X, Charles LF, Wang L, Aguila HL, Rowe DW, Lichtler AC, Goldberg AJ. Developmental-like bone regeneration by human embryonic stem cell-derived mesenchymal cells. Tissue Eng Part A. 2014 Jan; 20(1-2):365-77. PMID: 23952622; PMCID: PMC4350005.
    13. Ferrand A, Eap S, Richert L, Lemoine S, Kalaskar D, Demoustier-Champagne S, Atmani H, Mély Y, Fioretti F, Schlatter G, Kuhn L, Ladam G, Benkirane-Jessel N. Osteogenetic properties of electrospun nanofibrous PCL scaffolds equipped with chitosan-based nanoreservoirs of growth factors. Macromol Biosci. 2014 Jan; 14(1):45-55. PMID: 23956214.
      View in: PubMed
    14. Xu Y, Zanganeh S, Mohammad I, Aguirre A, Wang T, Yang Y, Kuhn L, Smith MB, Zhu Q. Targeting tumor hypoxia with 2-nitroimidazole-indocyanine green dye conjugates. J Biomed Opt. 2013 Jun; 18(6):66009. PMID: 23764695; PMCID: PMC3680745.
    15. Kuhn LT, Ou G, Charles L, Hurley MM, Rodner CM, Gronowicz G. Fibroblast growth factor-2 and bone morphogenetic protein-2 have a synergistic stimulatory effect on bone formation in cell cultures from elderly mouse and human bone. J Gerontol A Biol Sci Med Sci. 2013 Oct; 68(10):1170-80. PMID: 23531867; PMCID: PMC3826858.
    16. Catros S, Wen B, Schleier P, Shafer D, Dard M, Obrecht M, Freilich M, Kuhn L. Use of a perforated scaffold-retaining abutment to achieve vertical bone regeneration around dental implants in the minipig. Int J Oral Maxillofac Implants. 2013 Mar-Apr; 28(2):432-43. PMID: 23527345.
      View in: PubMed
    17. Liu Y, Charles LF, Zarembinski TI, Johnson KI, Atzet SK, Wesselschmidt RL, Wight ME, Kuhn LT. Modified hyaluronan hydrogels support the maintenance of mouse embryonic stem cells and human induced pluripotent stem cells. Macromol Biosci. 2012 Aug; 12(8):1034-42. PMID: 22730306.
      View in: PubMed
    18. Liu Y, Goldberg AJ, Dennis JE, Gronowicz GA, Kuhn LT. One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating. PLoS One. 2012; 7(3):e33225. PMID: 22457746; PMCID: PMC3310052.
    19. Freilich M, Wen B, Shafer D, Schleier P, Dard M, Pendrys D, Ortiz D, Kuhn L. Implant-guided vertical bone growth in the mini-pig. Clin Oral Implants Res. 2012 Jun; 23(6):751-7. PMID: 21810121.
      View in: PubMed
    20. Biswal NC, Pavlik C, Smith MB, Aguirre A, Xu Y, Zanganeh S, Kuhn LT, Claffey KP, Zhu Q. Imaging tumor hypoxia by near-infrared fluorescence tomography. J Biomed Opt. 2011 Jun; 16(6):066009. PMID: 21721810; PMCID: PMC3133800.
    21. Wen B, Karl M, Pendrys D, Shafer D, Freilich M, Kuhn L. An evaluation of BMP-2 delivery from scaffolds with miniaturized dental implants in a novel rat mandible model. J Biomed Mater Res B Appl Biomater. 2011 May; 97(2):315-26. PMID: 21394902.
      View in: PubMed
    22. Ou G, Charles L, Matton S, Rodner C, Hurley M, Kuhn L, Gronowicz G. Fibroblast growth factor-2 stimulates the proliferation of mesenchyme-derived progenitor cells from aging mouse and human bone. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1051-9. PMID: 20643704; PMCID: PMC2949335.
    23. Goldberg AJ, Liu Y, Advincula MC, Gronowicz G, Habibovic P, Kuhn LT. Fabrication and characterization of hydroxyapatite-coated polystyrene disks for use in osteoprogenitor cell culture. J Biomater Sci Polym Ed. 2010; 21(10):1371-87. PMID: 20534191.
      View in: PubMed
    24. Kuhn LT, Liu Y, Advincula M, Wang YH, Maye P, Goldberg AJ. A nondestructive method for evaluating in vitro osteoblast differentiation on biomaterials using osteoblast-specific fluorescence. Tissue Eng Part C Methods. 2010 Dec; 16(6):1357-66. PMID: 20337515.
      View in: PubMed
    25. Wang CJ, Chen IP, Koczon-Jaremko B, Boskey AL, Ueki Y, Kuhn L, Reichenberger EJ. Pro416Arg cherubism mutation in Sh3bp2 knock-in mice affects osteoblasts and alters bone mineral and matrix properties. Bone. 2010 May; 46(5):1306-15. PMID: 20117257; PMCID: PMC2854251.
    26. Freilich M, Shafer D, Wei M, Kompalli R, Adams D, Kuhn L. Implant system for guiding a new layer of bone. Computed microtomography and histomorphometric analysis in the rabbit mandible. Clin Oral Implants Res. 2009 Feb; 20(2):201-7. PMID: 19191797.
      View in: PubMed
    27. Kuhn LT, Grynpas MD, Rey CC, Wu Y, Ackerman JL, Glimcher MJ. A comparison of the physical and chemical differences between cancellous and cortical bovine bone mineral at two ages. Calcif Tissue Int. 2008 Aug; 83(2):146-54. PMID: 18685796.
      View in: PubMed
    28. Freilich M, M Patel C, Wei M, Shafer D, Schleier P, Hortschansky P, Kompali R, Kuhn L. Growth of new bone guided by implants in a murine calvarial model. Bone. 2008 Oct; 43(4):781-8. PMID: 18589010.
      View in: PubMed
    29. Ramesh M, Turner LF, Yadav R, Rajan TV, Vella AT, Kuhn LT. Effects of the physico-chemical nature of two biomimetic crystals on the innate immune response. Int Immunopharmacol. 2007 Dec 15; 7(13):1617-29. PMID: 17996671.
      View in: PubMed
    30. Cheng X, Kuhn L. Chemotherapy drug delivery from calcium phosphate nanoparticles. Int J Nanomedicine. 2007; 2(4):667-74. PMID: 18203433; PMCID: PMC2676798.
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