Keywords
Last Name
Institution

Brenton R Graveley PhD

TitleProfessor
InstitutionUConn Health Center
DepartmentGenetics and Developmental Biology
AddressMC 6403
Cell and Genome Sciences Building, MC 6403
400 Farmington Avenue
Phone860-679-2090
Fax860-679-8345
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Teng M, Love MI, Davis CA, Djebali S, Dobin A, Graveley BR, Li S, Mason CE, Olson S, Pervouchine D, Sloan CA, Wei X, Zhan L, Irizarry RA. A benchmark for RNA-seq quantification pipelines. Genome Biol. 2016; 17(1):74. PMID: 27107712.
      View in: PubMed
    2. Sundararaman B, Zhan L, Blue SM, Stanton R, Elkins K, Olson S, Wei X, Van Nostrand EL, Pratt GA, Huelga SC, Smalec BM, Wang X, Hong EL, Davidson JM, Lécuyer E, Graveley BR, Yeo GW. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016 Mar 17; 61(6):903-13. PMID: 26990993.
      View in: PubMed
    3. Taliaferro JM, Vidaki M, Oliveira R, Olson S, Zhan L, Saxena T, Wang ET, Graveley BR, Gertler FB, Swanson MS, Burge CB. Distal Alternative Last Exons Localize mRNAs to Neural Projections. Mol Cell. 2016 Mar 17; 61(6):821-33. PMID: 26907613.
      View in: PubMed
    4. Bolisetty MT, Rajadinakaran G, Graveley BR. Determining exon connectivity in complex mRNAs by nanopore sequencing. Genome Biol. 2015; 16(1):204. PMID: 26420219; PMCID: PMC4588896.
    5. Brooks AN, Duff MO, May G, Yang L, Bolisetty M, Landolin J, Wan K, Sandler J, Booth BW, Celniker SE, Graveley BR, Brenner SE. Regulation of alternative splicing in Drosophila by 56 RNA binding proteins. Genome Res. 2015 Nov; 25(11):1771-80. PMID: 26294686; PMCID: PMC4617972.
    6. Stoiber MH, Olson S, May GE, Duff MO, Manent J, Obar R, Guruharsha KG, Bickel PJ, Artavanis-Tsakonas S, Brown JB, Graveley BR, Celniker SE. Extensive cross-regulation of post-transcriptional regulatory networks in Drosophila. Genome Res. 2015 Nov; 25(11):1692-702. PMID: 26294687; PMCID: PMC4617965.
    7. Coolon JD, Stevenson KR, McManus CJ, Yang B, Graveley BR, Wittkopp PJ. Molecular Mechanisms and Evolutionary Processes Contributing to Accelerated Divergence of Gene Expression on the Drosophila X Chromosome. Mol Biol Evol. 2015 Oct; 32(10):2605-15. PMID: 26041937; PMCID: PMC4592344 [Available on 10/01/16].
    8. Duff MO, Olson S, Wei X, Garrett SC, Osman A, Bolisetty M, Plocik A, Celniker SE, Graveley BR. Genome-wide identification of zero nucleotide recursive splicing in Drosophila. Nature. 2015 May 21; 521(7552):376-9. PMID: 25970244; PMCID: PMC4529404 [Available on 11/21/15].
    9. Majumdar S, Zhao P, Pfister NT, Compton M, Olson S, Glover CV, Wells L, Graveley BR, Terns RM, Terns MP. Three CRISPR-Cas immune effector complexes coexist in Pyrococcus furiosus. RNA. 2015 Jun; 21(6):1147-58. PMID: 25904135; PMCID: PMC4436667 [Available on 06/01/16].
    10. Roy CK, Olson S, Graveley BR, Zamore PD, Moore MJ. Assessing long-distance RNA sequence connectivity via RNA-templated DNA-DNA ligation. Elife. 2015; 4. PMID: 25866926; PMCID: PMC4442144.
    11. Graveley BR. Musings on 20 years of RNA. RNA. 2015 Apr; 21(4):506-7. PMID: 25780115; PMCID: PMC4371257.
    12. Presnyak V, Alhusaini N, Chen YH, Martin S, Morris N, Kline N, Olson S, Weinberg D, Baker KE, Graveley BR, Coller J. Codon optimality is a major determinant of mRNA stability. Cell. 2015 Mar 12; 160(6):1111-24. PMID: 25768907; PMCID: PMC4359748 [Available on 03/12/16].
    13. Alon S, Garrett SC, Levanon EY, Olson S, Graveley BR, Rosenthal JJ, Eisenberg E. The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing. Elife. 2015; 4. PMID: 25569156; PMCID: PMC4384741.
    14. Westholm JO, Miura P, Olson S, Shenker S, Joseph B, Sanfilippo P, Celniker SE, Graveley BR, Lai EC. Genome-wide analysis of drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation. Cell Rep. 2014 Dec 11; 9(5):1966-80. PMID: 25544350; PMCID: PMC4279448 [Available on 12/11/15].
    15. Lee H, McManus CJ, Cho DY, Eaton M, Renda F, Somma MP, Cherbas L, May G, Powell S, Zhang D, Zhan L, Resch A, Andrews J, Celniker SE, Cherbas P, Przytycka TM, Gatti M, Oliver B, Graveley B, MacAlpine D. DNA copy number evolution in Drosophila cell lines. Genome Biol. 2014; 15(8):R70. PMID: 25262759; PMCID: PMC4289277.
    16. Brown JB, Boley N, Eisman R, May GE, Stoiber MH, Duff MO, Booth BW, Wen J, Park S, Suzuki AM, Wan KH, Yu C, Zhang D, Carlson JW, Cherbas L, Eads BD, Miller D, Mockaitis K, Roberts J, Davis CA, Frise E, Hammonds AS, Olson S, Shenker S, Sturgill D, Samsonova AA, Weiszmann R, Robinson G, Hernandez J, Andrews J, Bickel PJ, Carninci P, Cherbas P, Gingeras TR, Hoskins RA, Kaufman TC, Lai EC, Oliver B, Perrimon N, Graveley BR, Celniker SE. Diversity and dynamics of the Drosophila transcriptome. Nature. 2014 Aug 28; 512(7515):393-9. PMID: 24670639; PMCID: PMC4152413.
    17. Gerstein MB, Rozowsky J, Yan KK, Wang D, Cheng C, Brown JB, Davis CA, Hillier L, Sisu C, Li JJ, Pei B, Harmanci AO, Duff MO, Djebali S, Alexander RP, Alver BH, Auerbach R, Bell K, Bickel PJ, Boeck ME, Boley NP, Booth BW, Cherbas L, Cherbas P, Di C, Dobin A, Drenkow J, Ewing B, Fang G, Fastuca M, Feingold EA, Frankish A, Gao G, Good PJ, Guigó R, Hammonds A, Harrow J, Hoskins RA, Howald C, Hu L, Huang H, Hubbard TJ, Huynh C, Jha S, Kasper D, Kato M, Kaufman TC, Kitchen RR, Ladewig E, Lagarde J, Lai E, Leng J, Lu Z, MacCoss M, May G, McWhirter R, Merrihew G, Miller DM, Mortazavi A, Murad R, Oliver B, Olson S, Park PJ, Pazin MJ, Perrimon N, Pervouchine D, Reinke V, Reymond A, Robinson G, Samsonova A, Saunders GI, Schlesinger F, Sethi A, Slack FJ, Spencer WC, Stoiber MH, Strasbourger P, Tanzer A, Thompson OA, Wan KH, Wang G, Wang H, Watkins KL, Wen J, Wen K, Xue C, Yang L, Yip K, Zaleski C, Zhang Y, Zheng H, Brenner SE, Graveley BR, Celniker SE, Gingeras TR, Waterston R. Comparative analysis of the transcriptome across distant species. Nature. 2014 Aug 28; 512(7515):445-8. PMID: 25164755; PMCID: PMC4155737.
    18. Germain ND, Chen PF, Plocik AM, Glatt-Deeley H, Brown J, Fink JJ, Bolduc KA, Robinson TM, Levine ES, Reiter LT, Graveley BR, Lalande M, Chamberlain SJ. Gene expression analysis of human induced pluripotent stem cell-derived neurons carrying copy number variants of chromosome 15q11-q13.1. Mol Autism. 2014; 5:44. PMID: 25694803; PMCID: PMC4332023.
    19. Chen ZX, Sturgill D, Qu J, Jiang H, Park S, Boley N, Suzuki AM, Fletcher AR, Plachetzki DC, FitzGerald PC, Artieri CG, Atallah J, Barmina O, Brown JB, Blankenburg KP, Clough E, Dasgupta A, Gubbala S, Han Y, Jayaseelan JC, Kalra D, Kim YA, Kovar CL, Lee SL, Li M, Malley JD, Malone JH, Mathew T, Mattiuzzo NR, Munidasa M, Muzny DM, Ongeri F, Perales L, Przytycka TM, Pu LL, Robinson G, Thornton RL, Saada N, Scherer SE, Smith HE, Vinson C, Warner CB, Worley KC, Wu YQ, Zou X, Cherbas P, Kellis M, Eisen MB, Piano F, Kionte K, Fitch DH, Sternberg PW, Cutter AD, Duff MO, Hoskins RA, Graveley BR, Gibbs RA, Bickel PJ, Kopp A, Carninci P, Celniker SE, Oliver B, Richards S. Comparative validation of the D. melanogaster modENCODE transcriptome annotation. Genome Res. 2014 Jul; 24(7):1209-23. PMID: 24985915; PMCID: PMC4079975.
    20. Carte J, Christopher RT, Smith JT, Olson S, Barrangou R, Moineau S, Glover CV, Graveley BR, Terns RM, Terns MP. The three major types of CRISPR-Cas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus. Mol Microbiol. 2014 Jul; 93(1):98-112. PMID: 24811454; PMCID: PMC4095994.
    21. Coolon JD, McManus CJ, Stevenson KR, Graveley BR, Wittkopp PJ. Tempo and mode of regulatory evolution in Drosophila. Genome Res. 2014 May; 24(5):797-808. PMID: 24567308; PMCID: PMC4009609.
    22. McManus CJ, Coolon JD, Eipper-Mains J, Wittkopp PJ, Graveley BR. Evolution of splicing regulatory networks in Drosophila. Genome Res. 2014 May; 24(5):786-96. PMID: 24515119; PMCID: PMC4009608.
    23. Miura SK, Martins A, Zhang KX, Graveley BR, Zipursky SL. Probabilistic splicing of Dscam1 establishes identity at the level of single neurons. Cell. 2013 Nov 21; 155(5):1166-77. PMID: 24267895; PMCID: PMC3950301.
    24. Bolisetty MT, Graveley BR. Circuitous route to transcription regulation. Mol Cell. 2013 Sep 26; 51(6):705-6. PMID: 24074951; PMCID: PMC3839245.
    25. Sasidharan V, Lu YC, Bansal D, Dasari P, Poduval D, Seshasayee A, Resch AM, Graveley BR, Palakodeti D. Identification of neoblast- and regeneration-specific miRNAs in the planarian Schmidtea mediterranea. RNA. 2013 Oct; 19(10):1394-404. PMID: 23974438; PMCID: PMC3854530.
    26. Marinotti O, Cerqueira GC, de Almeida LG, Ferro MI, Loreto EL, Zaha A, Teixeira SM, Wespiser AR, Almeida E Silva A, Schlindwein AD, Pacheco AC, Silva AL, Graveley BR, Walenz BP, Lima Bde A, Ribeiro CA, Nunes-Silva CG, de Carvalho CR, Soares CM, de Menezes CB, Matiolli C, Caffrey D, Araújo DA, de Oliveira DM, Golenbock D, Grisard EC, Fantinatti-Garboggini F, de Carvalho FM, Barcellos FG, Prosdocimi F, May G, Azevedo Junior GM, Guimarães GM, Goldman GH, Padilha IQ, Batista Jda S, Ferro JA, Ribeiro JM, Fietto JL, Dabbas KM, Cerdeira L, Agnez-Lima LF, Brocchi M, de Carvalho MO, Teixeira Mde M, Diniz Maia Mde M, Goldman MH, Cruz Schneider MP, Felipe MS, Hungria M, Nicolás MF, Pereira M, Montes MA, Cantão ME, Vincentz M, Rafael MS, Silverman N, Stoco PH, Souza RC, Vicentini R, Gazzinelli RT, Neves Rde O, Silva R, Astolfi-Filho S, Maciel TE, Urményi TP, Tadei WP, Camargo EP, de Vasconcelos AT. The genome of Anopheles darlingi, the main neotropical malaria vector. Nucleic Acids Res. 2013 Aug; 41(15):7387-400. PMID: 23761445; PMCID: PMC3753621.
    27. Graveley BR. Tips for preparing mRNA-Seq libraries from poly(A)+ mRNA for Illumina transcriptome high-throughput sequencing. Cold Spring Harb Protoc. 2013 May; 2013(5):482-4. PMID: 23637362.
      View in: PubMed
    28. Doolittle WF, Fraser P, Gerstein MB, Graveley BR, Henikoff S, Huttenhower C, Oshlack A, Ponting CP, Rinn JL, Schatz MC, Ule J, Weigel D, Weinstock GM. Sixty years of genome biology. Genome Biol. 2013; 14(4):113. PMID: 23651518; PMCID: PMC3663092.
    29. Elmore JR, Yokooji Y, Sato T, Olson S, Glover CV, Graveley BR, Atomi H, Terns RM, Terns MP. Programmable plasmid interference by the CRISPR-Cas system in Thermococcus kodakarensis. RNA Biol. 2013 May; 10(5):828-40. PMID: 23535213; PMCID: PMC3737340.
    30. Braunschweig U, Gueroussov S, Plocik AM, Graveley BR, Blencowe BJ. Dynamic integration of splicing within gene regulatory pathways. Cell. 2013 Mar 14; 152(6):1252-69. PMID: 23498935; PMCID: PMC3642998.
    31. Plocik AM, Graveley BR. New insights from existing sequence data: generating breakthroughs without a pipette. Mol Cell. 2013 Feb 21; 49(4):605-17. PMID: 23438857; PMCID: PMC3590807.
    32. Eipper-Mains JE, Kiraly DD, Duff MO, Horowitz MJ, McManus CJ, Eipper BA, Graveley BR, Mains RE. Effects of cocaine and withdrawal on the mouse nucleus accumbens transcriptome. Genes Brain Behav. 2013 Feb; 12(1):21-33. PMID: 23094851; PMCID: PMC3553295.
    33. Coolon JD, Stevenson KR, McManus CJ, Graveley BR, Wittkopp PJ. Genomic imprinting absent in Drosophila melanogaster adult females. Cell Rep. 2012 Jul 26; 2(1):69-75. PMID: 22840398; PMCID: PMC3565465.
    34. Resch AM, Palakodeti D, Lu YC, Horowitz M, Graveley BR. Transcriptome analysis reveals strain-specific and conserved stemness genes in Schmidtea mediterranea. PLoS One. 2012; 7(4):e34447. PMID: 22496805; PMCID: PMC3319590.
    35. Smibert P, Miura P, Westholm JO, Shenker S, May G, Duff MO, Zhang D, Eads BD, Carlson J, Brown JB, Eisman RC, Andrews J, Kaufman T, Cherbas P, Celniker SE, Graveley BR, Lai EC. Global patterns of tissue-specific alternative polyadenylation in Drosophila. Cell Rep. 2012 Mar 29; 1(3):277-89. PMID: 22685694; PMCID: PMC3368434.
    36. Hale CR, Majumdar S, Elmore J, Pfister N, Compton M, Olson S, Resch AM, Glover CV, Graveley BR, Terns RM, Terns MP. Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs. Mol Cell. 2012 Feb 10; 45(3):292-302. PMID: 22227116; PMCID: PMC3278580.
    37. Graveley BR. Splicing up pluripotency. Cell. 2011 Sep 30; 147(1):22-4. PMID: 21962502.
      View in: PubMed
    38. Hollenbach JP, Resch AM, Palakodeti D, Graveley BR, Heinen CD. Loss of DNA mismatch repair imparts a selective advantage in planarian adult stem cells. PLoS One. 2011; 6(7):e21808. PMID: 21747960; PMCID: PMC3128615.
    39. Eipper-Mains JE, Kiraly DD, Palakodeti D, Mains RE, Eipper BA, Graveley BR. microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs. RNA. 2011 Aug; 17(8):1529-43. PMID: 21708909; PMCID: PMC3153976.
    40. McManus CJ, Graveley BR. RNA structure and the mechanisms of alternative splicing. Curr Opin Genet Dev. 2011 Aug; 21(4):373-9. PMID: 21530232; PMCID: PMC3149766.
    41. Graveley BR. Getting in the loop: new insights into the mechanism of poly(A) site recognition. Structure. 2011 Mar 9; 19(3):279-81. PMID: 21397179.
      View in: PubMed
    42. Yang L, Duff MO, Graveley BR, Carmichael GG, Chen LL. Genomewide characterization of non-polyadenylated RNAs. Genome Biol. 2011; 12(2):R16. PMID: 21324177; PMCID: PMC3188798.
    43. Hoskins RA, Landolin JM, Brown JB, Sandler JE, Takahashi H, Lassmann T, Yu C, Booth BW, Zhang D, Wan KH, Yang L, Boley N, Andrews J, Kaufman TC, Graveley BR, Bickel PJ, Carninci P, Carlson JW, Celniker SE. Genome-wide analysis of promoter architecture in Drosophila melanogaster. Genome Res. 2011 Feb; 21(2):182-92. PMID: 21177961; PMCID: PMC3032922.
    44. Graveley BR, Brooks AN, Carlson JW, Duff MO, Landolin JM, Yang L, Artieri CG, van Baren MJ, Boley N, Booth BW, Brown JB, Cherbas L, Davis CA, Dobin A, Li R, Lin W, Malone JH, Mattiuzzo NR, Miller D, Sturgill D, Tuch BB, Zaleski C, Zhang D, Blanchette M, Dudoit S, Eads B, Green RE, Hammonds A, Jiang L, Kapranov P, Langton L, Perrimon N, Sandler JE, Wan KH, Willingham A, Zhang Y, Zou Y, Andrews J, Bickel PJ, Brenner SE, Brent MR, Cherbas P, Gingeras TR, Hoskins RA, Kaufman TC, Oliver B, Celniker SE. The developmental transcriptome of Drosophila melanogaster. Nature. 2011 Mar 24; 471(7339):473-9. PMID: 21179090; PMCID: PMC3075879.
    45. Cherbas L, Willingham A, Zhang D, Yang L, Zou Y, Eads BD, Carlson JW, Landolin JM, Kapranov P, Dumais J, Samsonova A, Choi JH, Roberts J, Davis CA, Tang H, van Baren MJ, Ghosh S, Dobin A, Bell K, Lin W, Langton L, Duff MO, Tenney AE, Zaleski C, Brent MR, Hoskins RA, Kaufman TC, Andrews J, Graveley BR, Perrimon N, Celniker SE, Gingeras TR, Cherbas P. The transcriptional diversity of 25 Drosophila cell lines. Genome Res. 2011 Feb; 21(2):301-14. PMID: 21177962; PMCID: PMC3032933.
    46. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science. 2010 Dec 24; 330(6012):1787-97. PMID: 21177974; PMCID: PMC3192495.
    47. May GE, Olson S, McManus CJ, Graveley BR. Competing RNA secondary structures are required for mutually exclusive splicing of the Dscam exon 6 cluster. RNA. 2011 Feb; 17(2):222-9. PMID: 21159795; PMCID: PMC3022272.
    48. Brooks AN, Yang L, Duff MO, Hansen KD, Park JW, Dudoit S, Brenner SE, Graveley BR. Conservation of an RNA regulatory map between Drosophila and mammals. Genome Res. 2011 Feb; 21(2):193-202. PMID: 20921232; PMCID: PMC3032923.
    49. McManus CJ, Duff MO, Eipper-Mains J, Graveley BR. Global analysis of trans-splicing in Drosophila. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):12975-9. PMID: 20615941; PMCID: PMC2919919.
    50. McManus CJ, Coolon JD, Duff MO, Eipper-Mains J, Graveley BR, Wittkopp PJ. Regulatory divergence in Drosophila revealed by mRNA-seq. Genome Res. 2010 Jun; 20(6):816-25. PMID: 20354124; PMCID: PMC2877578.
    51. Nilsen TW, Graveley BR. Expansion of the eukaryotic proteome by alternative splicing. Nature. 2010 Jan 28; 463(7280):457-63. PMID: 20110989; PMCID: PMC3443858.
    52. Hale CR, Zhao P, Olson S, Duff MO, Graveley BR, Wells L, Terns RM, Terns MP. RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex. Cell. 2009 Nov 25; 139(5):945-56. PMID: 19945378; PMCID: PMC2951265.
    53. Lee C, Kim N, Roy M, Graveley BR. Massive expansions of Dscam splicing diversity via staggered homologous recombination during arthropod evolution. RNA. 2010 Jan; 16(1):91-105. PMID: 19934230; PMCID: PMC2802040.
    54. Lu YC, Smielewska M, Palakodeti D, Lovci MT, Aigner S, Yeo GW, Graveley BR. Deep sequencing identifies new and regulated microRNAs in Schmidtea mediterranea. RNA. 2009 Aug; 15(8):1483-91. PMID: 19553344; PMCID: PMC2714757.
    55. Graveley BR. Alternative splicing: regulation without regulators. Nat Struct Mol Biol. 2009 Jan; 16(1):13-5. PMID: 19125169; PMCID: PMC2732116.
    56. McManus CJ, Graveley BR. Getting the message out. Mol Cell. 2008 Jul 11; 31(1):4-6. PMID: 18614041; PMCID: PMC2713004.
    57. Graveley BR. Molecular biology: power sequencing. Nature. 2008 Jun 26; 453(7199):1197-8. PMID: 18580940; PMCID: PMC4386836.
    58. Palakodeti D, Smielewska M, Lu YC, Yeo GW, Graveley BR. The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians. RNA. 2008 Jun; 14(6):1174-86. PMID: 18456843; PMCID: PMC2390803.
    59. Graveley BR. The haplo-spliceo-transcriptome: common variations in alternative splicing in the human population. Trends Genet. 2008 Jan; 24(1):5-7. PMID: 18054116; PMCID: PMC2372159.
    60. Olson S, Blanchette M, Park J, Savva Y, Yeo GW, Yeakley JM, Rio DC, Graveley BR. A regulator of Dscam mutually exclusive splicing fidelity. Nat Struct Mol Biol. 2007 Dec; 14(12):1134-40. PMID: 21188797; PMCID: PMC3050534.
    61. Yang L, Park J, Graveley BR. Splicing from the outside in. Mol Cell. 2007 Sep 21; 27(6):861-2. PMID: 17889658; PMCID: PMC2376043.
    62. Park JW, Graveley BR. Complex alternative splicing. Adv Exp Med Biol. 2007; 623:50-63. PMID: 18380340; PMCID: PMC4387867.
    63. Palakodeti D, Smielewska M, Graveley BR. MicroRNAs from the Planarian Schmidtea mediterranea: a model system for stem cell biology. RNA. 2006 Sep; 12(9):1640-9. PMID: 16849698; PMCID: PMC1557691.
    64. Black DL, Graveley BR. Splicing bioinformatics to biology. Genome Biol. 2006; 7(5):317. PMID: 16732900; PMCID: PMC1779529.
    65. Park JW, Graveley BR. Use of RNA interference to dissect the roles of trans-acting factors in alternative pre-mRNA splicing. Methods. 2005 Dec; 37(4):341-4. PMID: 16314263; PMCID: PMC2373254.
    66. Graveley BR. Coordinated control of splicing and translation. Nat Struct Mol Biol. 2005 Dec; 12(12):1022-3. PMID: 16327769; PMCID: PMC2427160.
    67. Kreahling JM, Graveley BR. The iStem, a long-range RNA secondary structure element required for efficient exon inclusion in the Drosophila Dscam pre-mRNA. Mol Cell Biol. 2005 Dec; 25(23):10251-60. PMID: 16287842; PMCID: PMC1291239.
    68. Graveley BR. Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures. Cell. 2005 Oct 7; 123(1):65-73. PMID: 16213213; PMCID: PMC2366815.
    69. Hertel KJ, Graveley BR. RS domains contact the pre-mRNA throughout spliceosome assembly. Trends Biochem Sci. 2005 Mar; 30(3):115-8. PMID: 15752982.
      View in: PubMed
    70. Graveley BR. Small molecule control of pre-mRNA splicing. RNA. 2005 Mar; 11(3):355-8. PMID: 15661847; PMCID: PMC1370724.
    71. Celotto AM, Lee JW, Graveley BR. Exon-specific RNA interference: a tool to determine the functional relevance of proteins encoded by alternatively spliced mRNAs. Methods Mol Biol. 2005; 309:273-82. PMID: 15990407; PMCID: PMC2376763.
    72. Philipps DL, Park JW, Graveley BR. A computational and experimental approach toward a priori identification of alternatively spliced exons. RNA. 2004 Dec; 10(12):1838-44. PMID: 15525709; PMCID: PMC1370671.
    73. Park JW, Parisky K, Celotto AM, Reenan RA, Graveley BR. Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci U S A. 2004 Nov 9; 101(45):15974-9. PMID: 15492211; PMCID: PMC528766.
    74. Graveley BR, Kaur A, Gunning D, Zipursky SL, Rowen L, Clemens JC. The organization and evolution of the dipteran and hymenopteran Down syndrome cell adhesion molecule (Dscam) genes. RNA. 2004 Oct; 10(10):1499-506. PMID: 15383675; PMCID: PMC1370636.
    75. Graveley BR. A protein interaction domain contacts RNA in the prespliceosome. Mol Cell. 2004 Feb 13; 13(3):302-4. PMID: 14967137.
      View in: PubMed
    76. Kreahling J, Graveley BR. The origins and implications of Aluternative splicing. Trends Genet. 2004 Jan; 20(1):1-4. PMID: 14698612.
      View in: PubMed
    77. Celotto AM, Graveley BR. RNA interference of mRNA processing factors in Drosophila S2 cells. Methods Mol Biol. 2004; 257:245-54. PMID: 14770010; PMCID: PMC2376805.
    78. Celotto AM, Graveley BR. Using single-strand conformational polymorphism gel electrophoresis to analyze mutually exclusive alternative splicing. Methods Mol Biol. 2004; 257:65-74. PMID: 14769996; PMCID: PMC2376758.
    79. Philipps D, Celotto AM, Wang QQ, Tarng RS, Graveley BR. Arginine/serine repeats are sufficient to constitute a splicing activation domain. Nucleic Acids Res. 2003 Nov 15; 31(22):6502-8. PMID: 14602908; PMCID: PMC275541.
    80. Lam BJ, Bakshi A, Ekinci FY, Webb J, Graveley BR, Hertel KJ. Enhancer-dependent 5'-splice site control of fruitless pre-mRNA splicing. J Biol Chem. 2003 Jun 20; 278(25):22740-7. PMID: 12646561; PMCID: PMC2386364.
    81. Szymczyna BR, Bowman J, McCracken S, Pineda-Lucena A, Lu Y, Cox B, Lambermon M, Graveley BR, Arrowsmith CH, Blencowe BJ. Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing. Genes Dev. 2003 Feb 15; 17(4):461-75. PMID: 12600940; PMCID: PMC196000.
    82. Celotto AM, Graveley BR. Exon-specific RNAi: a tool for dissecting the functional relevance of alternative splicing. RNA. 2002 Jun; 8(6):718-24. PMID: 12088145; PMCID: PMC1370291.
    83. Graveley BR. Sex, AGility, and the regulation of alternative splicing. Cell. 2002 May 17; 109(4):409-12. PMID: 12086596.
      View in: PubMed
    84. Rowen L, Young J, Birditt B, Kaur A, Madan A, Philipps DL, Qin S, Minx P, Wilson RK, Hood L, Graveley BR. Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity. Genomics. 2002 Apr; 79(4):587-97. PMID: 11944992.
      View in: PubMed
    85. Shepard J, Reick M, Olson S, Graveley BR. Characterization of U2AF(6), a splicing factor related to U2AF(35). Mol Cell Biol. 2002 Jan; 22(1):221-30. PMID: 11739736; PMCID: PMC134218.
    86. Celotto AM, Graveley BR. Alternative splicing of the Drosophila Dscam pre-mRNA is both temporally and spatially regulated. Genetics. 2001 Oct; 159(2):599-608. PMID: 11606537; PMCID: PMC1461822.
    87. Graveley BR, Hertel KJ, Maniatis T. The role of U2AF35 and U2AF65 in enhancer-dependent splicing. RNA. 2001 Jun; 7(6):806-18. PMID: 11421359; PMCID: PMC1370132.
    88. Graveley BR. Alternative splicing: increasing diversity in the proteomic world. Trends Genet. 2001 Feb; 17(2):100-7. PMID: 11173120.
      View in: PubMed
    89. Graveley BR. Sorting out the complexity of SR protein functions. RNA. 2000 Sep; 6(9):1197-211. PMID: 10999598; PMCID: PMC1369994.
    90. Graveley BR, Hertel KJ, Maniatis T. SR proteins are 'locators' of the RNA splicing machinery. Curr Biol. 1999 Jan 14; 9(1):R6-7. PMID: 9889128.
      View in: PubMed
    91. Graveley BR, Hertel KJ, Maniatis T. A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers. EMBO J. 1998 Nov 16; 17(22):6747-56. PMID: 9822617; PMCID: PMC1171020.
    92. Graveley BR, Maniatis T. Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing. Mol Cell. 1998 Apr; 1(5):765-71. PMID: 9660960.
      View in: PubMed
    93. Graveley BR, Fleming ES, Gilmartin GM. Restoration of both structure and function to a defective poly(A) site by in vitro selection. J Biol Chem. 1996 Dec 27; 271(52):33654-63. PMID: 8969235.
      View in: PubMed
    94. Schnapp G, Graveley BR, Grummt I. TFIIS binds to mouse RNA polymerase I and stimulates transcript elongation and hydrolytic cleavage of nascent rRNA. Mol Gen Genet. 1996 Sep 25; 252(4):412-9. PMID: 8879242.
      View in: PubMed
    95. Graveley BR, Fleming ES, Gilmartin GM. RNA structure is a critical determinant of poly(A) site recognition by cleavage and polyadenylation specificity factor. Mol Cell Biol. 1996 Sep; 16(9):4942-51. PMID: 8756653; PMCID: PMC231496.
    96. Graveley BR, Gilmartin GM. A common mechanism for the enhancement of mRNA 3' processing by U3 sequences in two distantly related lentiviruses. J Virol. 1996 Mar; 70(3):1612-7. PMID: 8627681; PMCID: PMC189984.
    97. Gilmartin GM, Fleming ES, Oetjen J, Graveley BR. CPSF recognition of an HIV-1 mRNA 3'-processing enhancer: multiple sequence contacts involved in poly(A) site definition. Genes Dev. 1995 Jan 1; 9(1):72-83. PMID: 7828853.
      View in: PubMed
    Graveley's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _