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Daniel W Rosenberg PhD

TitleProfessor
InstitutionUConn Health Center
DepartmentCenter for Molecular Medicine
AddressMC 3101
Academic Research Building, MC 3101
263 Farmington Avenue
Phone860-679-8704
Fax860-679-7639
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    Other Positions
    TitleProfessor
    InstitutionUConn Health Center
    DepartmentGenetics and Developmental Biology


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Drew DA, Goh G, Mo A, Grady JJ, Forouhar F, Egan G, Swede H, Rosenberg DW, Stevens RG, Devers TJ. Colorectal polyp prevention by daily aspirin use is abrogated among active smokers. Cancer Causes Control. 2016 Jan; 27(1):93-103. PMID: 26510933.
      View in: PubMed
    2. Brand M, Hollaender R, Rosenberg D, Scott M, Hunsche E, Tyndall A, Denaro V, Carreira P, Varju C, Gabrielli B, Zingarelli S, Caramaschi P, Simic-Pasalic K, Müller-Ladner U, Vasile M, Mihai C, Rosato E, Vacca A, Zenone T, Mohamed WA, Ancuta C, Zampogna G, Rednic S, Jabaar N, Belloli L, Pozzi MR, Foti R, Walker UA. An observational cohort study of patients with newly diagnosed digital ulcer disease secondary to systemic sclerosis registered in the EUSTAR database. Clin Exp Rheumatol. 2015 Jul-Aug; 33(4 Suppl 91):S47-54. PMID: 26243652.
      View in: PubMed
    3. Giardina C, Nakanishi M, Khan A, Kuratnik A, Xu W, Brenner B, Rosenberg DW. Regulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas. Cancer Prev Res (Phila). 2015 May; 8(5):387-99. PMID: 25873367; PMCID: PMC4417398 [Available on 05/01/16].
    4. Chen JH, Perry CJ, Tsui YC, Staron MM, Parish IA, Dominguez CX, Rosenberg DW, Kaech SM. Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection. Nat Med. 2015 Apr; 21(4):327-34. PMID: 25799228; PMCID: PMC4505619.
    5. Nakanishi M, Perret C, Meuillet EJ, Rosenberg DW. Non-cell autonomous effects of targeting inducible PGE2 synthesis during inflammation-associated colon carcinogenesis. Carcinogenesis. 2015 Apr; 36(4):478-86. PMID: 25634334; PMCID: PMC4392604 [Available on 04/01/16].
    6. Gillen DL, Meyskens FL, Morgan TR, Zell JA, Carroll R, Benya R, Chen WP, Mo A, Tucker C, Bhattacharya A, Huang Z, Arcilla M, Wong V, Chung J, Gonzalez R, Rodriguez LM, Szabo E, Rosenberg DW, Lipkin SM. A phase IIa randomized, double-blind trial of erlotinib in inhibiting epidermal growth factor receptor signaling in aberrant crypt foci of the colorectum. Cancer Prev Res (Phila). 2015 Mar; 8(3):222-30. PMID: 25604134; PMCID: PMC4355051 [Available on 03/01/16].
    7. Montrose DC, Nakanishi M, Murphy RC, Zarini S, McAleer JP, Vella AT, Rosenberg DW. The role of PGE2 in intestinal inflammation and tumorigenesis. Prostaglandins Other Lipid Mediat. 2015 Jan-Mar; 116-117:26-36. PMID: 25460828; PMCID: PMC4385488 [Available on 01/01/16].
    8. Hahn MA, Li AX, Wu X, Yang R, Drew DA, Rosenberg DW, Pfeifer GP. Loss of the polycomb mark from bivalent promoters leads to activation of cancer-promoting genes in colorectal tumors. Cancer Res. 2014 Jul 1; 74(13):3617-29. PMID: 24786786; PMCID: PMC4079738.
    9. Drew DA, Devers TJ, O'Brien MJ, Horelik NA, Levine J, Rosenberg DW. HD chromoendoscopy coupled with DNA mass spectrometry profiling identifies somatic mutations in microdissected human proximal aberrant crypt foci. Mol Cancer Res. 2014 Jun; 12(6):823-9. PMID: 24651453; PMCID: PMC4058342.
    10. Wang LS, Kuo CT, Stoner K, Yearsley M, Oshima K, Yu J, Huang TH, Rosenberg D, Peiffer D, Stoner G, Huang YW. Dietary black raspberries modulate DNA methylation in dextran sodium sulfate (DSS)-induced ulcerative colitis. Carcinogenesis. 2013 Dec; 34(12):2842-50. PMID: 24067901; PMCID: PMC3845896.
    11. Guillevin L, Hunsche E, Denton CP, Krieg T, Schwierin B, Rosenberg D, Matucci-Cerinic M. Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry. Clin Exp Rheumatol. 2013 Mar-Apr; 31(2 Suppl 76):71-80. PMID: 23910613.
      View in: PubMed
    12. Miyamoto S, Nakanishi M, Rosenberg DW. Suppression of colon carcinogenesis by targeting Notch signaling. Carcinogenesis. 2013 Oct; 34(10):2415-23. PMID: 23729655; PMCID: PMC3786381.
    13. Drew DA, Devers T, Horelik N, Yang S, O'Brien M, Wu R, Rosenberg DW. Nanoproteomic analysis of extracellular receptor kinase-1/2 post-translational activation in microdissected human hyperplastic colon lesions. Proteomics. 2013 May; 13(9):1428-36. PMID: 23467982; PMCID: PMC3805251.
    14. Morad SA, Madigan JP, Levin JC, Abdelmageed N, Karimi R, Rosenberg DW, Kester M, Shanmugavelandy SS, Cabot MC. Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53. Biochem Pharmacol. 2013 Apr 15; 85(8):1057-65. PMID: 23353700; PMCID: PMC3604153.
    15. Ménoret A, Drew DA, Miyamoto S, Nakanishi M, Vella AT, Rosenberg DW. Differential proteomics identifies PDIA3 as a novel chemoprevention target in human colon cancer cells. Mol Carcinog. 2014 Feb; 53 Suppl 1:E11-22. PMID: 23255428.
      View in: PubMed
    16. Nakanishi M, Rosenberg DW. Multifaceted roles of PGE2 in inflammation and cancer. Semin Immunopathol. 2013 Mar; 35(2):123-37. PMID: 22996682; PMCID: PMC3568185.
    17. Kadaveru K, Protiva P, Greenspan EJ, Kim YI, Rosenberg DW. Dietary methyl donor depletion protects against intestinal tumorigenesis in Apc(Min/+) mice. Cancer Prev Res (Phila). 2012 Jul; 5(7):911-20. PMID: 22677908; PMCID: PMC3397832.
    18. Anderson JC, Swede H, Rustagi T, Protiva P, Pleau D, Brenner BM, Rajan TV, Heinen CD, Levine JB, Rosenberg DW. Aberrant crypt foci as predictors of colorectal neoplasia on repeat colonoscopy. Cancer Causes Control. 2012 Feb; 23(2):355-61. PMID: 22187142.
      View in: PubMed
    19. Giardina C, Madigan JP, Tierney CA, Brenner BM, Rosenberg DW. Vitamin D resistance and colon cancer prevention. Carcinogenesis. 2012 Mar; 33(3):475-82. PMID: 22180570; PMCID: PMC3384070.
    20. Miyamoto S, Rosenberg DW. Role of Notch signaling in colon homeostasis and carcinogenesis. Cancer Sci. 2011 Nov; 102(11):1938-42. PMID: 21801279; PMCID: PMC3200455.
    21. Nakanishi M, Menoret A, Tanaka T, Miyamoto S, Montrose DC, Vella AT, Rosenberg DW. Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity. Cancer Prev Res (Phila). 2011 Aug; 4(8):1198-208. PMID: 21576350; PMCID: PMC3151318.
    22. Rigatti MJ, Verma R, Belinsky GS, Rosenberg DW, Giardina C. Pharmacological inhibition of Mdm2 triggers growth arrest and promotes DNA breakage in mouse colon tumors and human colon cancer cells. Mol Carcinog. 2012 May; 51(5):363-78. PMID: 21557332; PMCID: PMC3162984.
    23. O'Leary KE, Cruess DG, Pleau D, Swede H, Anderson J, Rosenberg D. Sex differences in associations between psychosocial factors and aberrant crypt foci among patients at risk for colon cancer. Gend Med. 2011 Jun; 8(3):165-71. PMID: 21543265.
      View in: PubMed
    24. Greenspan EJ, Madigan JP, Boardman LA, Rosenberg DW. Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}. Cancer Prev Res (Phila). 2011 Jan; 4(1):161-71. PMID: 21205744; PMCID: PMC3078769.
    25. Montrose DC, Horelik NA, Madigan JP, Stoner GD, Wang LS, Bruno RS, Park HJ, Giardina C, Rosenberg DW. Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis. Carcinogenesis. 2011 Mar; 32(3):343-50. PMID: 21098643; PMCID: PMC3047236.
    26. Cao L, Gibson JD, Miyamoto S, Sail V, Verma R, Rosenberg DW, Nelson CE, Giardina C. Intestinal lineage commitment of embryonic stem cells. Differentiation. 2011 Jan; 81(1):1-10. PMID: 20934799.
      View in: PubMed
    27. Greenspan EJ, Nichols FC, Rosenberg DW. Molecular alterations associated with sulindac-resistant colon tumors in ApcMin/+ mice. Cancer Prev Res (Phila). 2010 Sep; 3(9):1187-97. PMID: 20716632; PMCID: PMC2933289.
    28. Rosenberg DW. Colorectal cancer. Mutat Res. 2010 Nov 10; 693(1-2):1-2. PMID: 20599550.
      View in: PubMed
    29. Montrose DC, Kadaveru K, Ilsley JN, Root SH, Rajan TV, Ramesh M, Nichols FC, Liang BT, Sonin D, Hand AR, Zarini S, Murphy RC, Belinsky GS, Nakanishi M, Rosenberg DW. cPLA2 is protective against COX inhibitor-induced intestinal damage. Toxicol Sci. 2010 Sep; 117(1):122-32. PMID: 20562220; PMCID: PMC2923287.
    30. Winnicka B, O'Conor C, Schacke W, Vernier K, Grant CL, Fenteany FH, Pereira FE, Liang B, Kaur A, Zhao R, Montrose DC, Rosenberg DW, Aguila HL, Shapiro LH. CD13 is dispensable for normal hematopoiesis and myeloid cell functions in the mouse. J Leukoc Biol. 2010 Aug; 88(2):347-59. PMID: 20430777; PMCID: PMC2908940.
    31. Brenner BM, Rosenberg D. High-throughput SNP/CGH approaches for the analysis of genomic instability in colorectal cancer. Mutat Res. 2010 Nov 10; 693(1-2):46-52. PMID: 20416328.
      View in: PubMed
    32. Anderson JC, Pleau DC, Rajan TV, Protiva P, Swede H, Brenner B, Heinen CD, Lambrecht RW, Rosenberg DW. Increased frequency of serrated aberrant crypt foci among smokers. Am J Gastroenterol. 2010 Jul; 105(7):1648-54. PMID: 20234347.
      View in: PubMed
    33. Nakanishi M, Gokhale V, Meuillet EJ, Rosenberg DW. mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators". Biochimie. 2010 Jun; 92(6):660-4. PMID: 20159031; PMCID: PMC2898715.
    34. Park HJ, Davis SR, Liang HY, Rosenberg DW, Bruno RS. Chlorogenic acid differentially alters hepatic and small intestinal thiol redox status without protecting against azoxymethane-induced colon carcinogenesis in mice. Nutr Cancer. 2010; 62(3):362-70. PMID: 20358474.
      View in: PubMed
    35. Swede H, Rohan TE, Yu H, Anderson JC, Stevens RG, Brokaw J, Levine J, Brenner BM, Malchoff CD, Duffy VB, Pleau DC, Rosenberg DW. Number of aberrant crypt foci associated with adiposity and IGF1 bioavailability. Cancer Causes Control. 2009 Jul; 20(5):653-61. PMID: 19067190; PMCID: PMC3099467.
    36. Rosenberg DW, Giardina C, Tanaka T. Mouse models for the study of colon carcinogenesis. Carcinogenesis. 2009 Feb; 30(2):183-96. PMID: 19037092; PMCID: PMC2639048.
    37. Godman CA, Joshi R, Tierney BR, Greenspan E, Rasmussen TP, Wang HW, Shin DG, Rosenberg DW, Giardina C. HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Biol Ther. 2008 Oct; 7(10):1570-80. PMID: 18769117; PMCID: PMC2614677.
    38. Al-Salihi MA, Terrece Pearman A, Doan T, Reichert EC, Rosenberg DW, Prescott SM, Stafforini DM, Topham MK. Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression. Cancer Lett. 2009 Jan 18; 273(2):225-32. PMID: 18790560; PMCID: PMC2646674.
    39. Stevens RG, Pretlow TP, Hurlstone DP, Giardina C, Rosenberg DW. Comment re: "Sporadic aberrant crypt foci are not a surrogate endpoint for colorectal adenoma prevention" and "Aberrant crypt foci in the adenoma prevention with celecoxib trial". Cancer Prev Res (Phila). 2008 Aug; 1(3):215-6; author reply 216. PMID: 19138959.
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    40. Nakanishi M, Montrose DC, Clark P, Nambiar PR, Belinsky GS, Claffey KP, Xu D, Rosenberg DW. Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis. Cancer Res. 2008 May 1; 68(9):3251-9. PMID: 18451151.
      View in: PubMed
    41. Spurling CC, Godman CA, Noonan EJ, Rasmussen TP, Rosenberg DW, Giardina C. HDAC3 overexpression and colon cancer cell proliferation and differentiation. Mol Carcinog. 2008 Feb; 47(2):137-47. PMID: 17849419.
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    42. Mounier CM, Wendum D, Greenspan E, Fléjou JF, Rosenberg DW, Lambeau G. Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate. Br J Cancer. 2008 Feb 12; 98(3):587-95. PMID: 18212756; PMCID: PMC2243149.
    43. Spurling CC, Suhl JA, Boucher N, Nelson CE, Rosenberg DW, Giardina C. The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells. Nutr Cancer. 2008; 60(5):692-702. PMID: 18791934.
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    44. Nakanishi M, Ménoret A, Belinsky GS, Giardina C, Godman CA, Vella AT, Rosenberg DW. Utilizing endoscopic technology to reveal real-time proteomic alterations in response to chemoprevention. Proteomics Clin Appl. 2007 Dec; 1(12):1660-6. PMID: 21136663.
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    45. Guda K, Marino JN, Jung Y, Crary K, Dong M, Rosenberg DW. Strain-specific homeostatic responses during early stages of Azoxymethane-induced colon tumorigenesis in mice. Int J Oncol. 2007 Oct; 31(4):837-42. PMID: 17786315.
      View in: PubMed
    46. Fleming ES, Zajac M, Moschenross DM, Montrose DC, Rosenberg DW, Cowan AE, Tirnauer JS. Planar spindle orientation and asymmetric cytokinesis in the mouse small intestine. J Histochem Cytochem. 2007 Nov; 55(11):1173-80. PMID: 17712178; PMCID: PMC3957531.
    47. Rosenberg DW, Yang S, Pleau DC, Greenspan EJ, Stevens RG, Rajan TV, Heinen CD, Levine J, Zhou Y, O'Brien MJ. Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans. Cancer Res. 2007 Apr 15; 67(8):3551-4. PMID: 17440063.
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    48. Belinsky GS, Parke AL, Huang Q, Blanchard K, Jayadev S, Stoll R, Rothe M, Achenie LE, Gupta RR, Wu GY, Rosenberg DW. The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun; 97(2):582-94. PMID: 17400583.
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    49. Belinsky GS, Rajan TV, Saria EA, Giardina C, Rosenberg DW. Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth. Mol Carcinog. 2007 Feb; 46(2):106-16. PMID: 17091473.
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    50. Flynn C, Montrose DC, Swank DL, Nakanishi M, Ilsley JN, Rosenberg DW. Deoxycholic acid promotes the growth of colonic aberrant crypt foci. Mol Carcinog. 2007 Jan; 46(1):60-70. PMID: 17091474.
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    51. Stevens RG, Swede H, Rosenberg DW. Epidemiology of colonic aberrant crypt foci: review and analysis of existing studies. Cancer Lett. 2007 Jul 18; 252(2):171-83. PMID: 17182176; PMCID: PMC2017093.
    52. Greenspan EJ, Cyr JL, Pleau DC, Levine J, Rajan TV, Rosenberg DW, Heinen CD. Microsatellite instability in aberrant crypt foci from patients without concurrent colon cancer. Carcinogenesis. 2007 Apr; 28(4):769-76. PMID: 17088260.
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    53. Kohno M, Momoi M, Oo ML, Paik JH, Lee YM, Venkataraman K, Ai Y, Ristimaki AP, Fyrst H, Sano H, Rosenberg D, Saba JD, Proia RL, Hla T. Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation. Mol Cell Biol. 2006 Oct; 26(19):7211-23. PMID: 16980623; PMCID: PMC1592880.
    54. Nakanishi M, Rosenberg DW. Roles of cPLA2alpha and arachidonic acid in cancer. Biochim Biophys Acta. 2006 Nov; 1761(11):1335-43. PMID: 17052951; PMCID: PMC1761949.
    55. Stevens RG, Swede H, Heinen CD, Jablonski M, Grupka M, Ross B, Parente M, Tirnauer JS, Giardina C, Rajan TV, Rosenberg DW, Levine J. Aberrant crypt foci in patients with a positive family history of sporadic colorectal cancer. Cancer Lett. 2007 Apr 18; 248(2):262-8. PMID: 16950561.
      View in: PubMed
    56. Aizu W, Belinsky GS, Flynn C, Noonan EJ, Boes CC, Godman CA, Doshi B, Nambiar PR, Rosenberg DW, Giardina C. Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors. Biochem Pharmacol. 2006 Oct 16; 72(8):981-91. PMID: 16949053.
      View in: PubMed
    57. Mann JR, Backlund MG, Buchanan FG, Daikoku T, Holla VR, Rosenberg DW, Dey SK, DuBois RN. Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression. Cancer Res. 2006 Jul 1; 66(13):6649-56. PMID: 16818638.
      View in: PubMed
    58. Greenspan EJ, Jablonski MA, Rajan TV, Levine J, Belinsky GS, Rosenberg DW. Epigenetic alterations in RASSF1A in human aberrant crypt foci. Carcinogenesis. 2006 Jul; 27(7):1316-22. PMID: 16513682; PMCID: PMC3117759.
    59. Nambiar PR, Boutin SR, Raja R, Rosenberg DW. Global gene expression profiling: a complement to conventional histopathologic analysis of neoplasia. Vet Pathol. 2005 Nov; 42(6):735-52. PMID: 16301570.
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    60. Belinsky GS, Claffey KP, Nambiar PR, Guda K, Rosenberg DW. Vascular endothelial growth factor and enhanced angiogenesis do not promote metastatic conversion of a newly established azoxymethane-induced colon cancer cell line. Mol Carcinog. 2005 Jun; 43(2):65-74. PMID: 15768385.
      View in: PubMed
    61. Ilsley JN, Nakanishi M, Flynn C, Belinsky GS, De Guise S, Adib JN, Dobrowsky RT, Bonventre JV, Rosenberg DW. Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis. Cancer Res. 2005 Apr 1; 65(7):2636-43. PMID: 15805260.
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    62. Dong M, Johnson M, Rezaie A, Ilsley JN, Nakanishi M, Sanders MM, Forouhar F, Levine J, Montrose DC, Giardina C, Rosenberg DW. Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis. Clin Cancer Res. 2005 Mar 15; 11(6):2265-71. PMID: 15788676.
      View in: PubMed
    63. Tong X, Yin L, Joshi S, Rosenberg DW, Giardina C. Cyclooxygenase-2 regulation in colon cancer cells: modulation of RNA polymerase II elongation by histone deacetylase inhibitors. J Biol Chem. 2005 Apr 22; 280(16):15503-9. PMID: 15713675.
      View in: PubMed
    64. Tong X, Yin L, Washington R, Rosenberg DW, Giardina C. The p50-p50 NF-kappaB complex as a stimulus-specific repressor of gene activation. Mol Cell Biochem. 2004 Oct; 265(1-2):171-83. PMID: 15543947.
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    65. Nambiar PR, Nakanishi M, Gupta R, Cheung E, Firouzi A, Ma XJ, Flynn C, Dong M, Guda K, Levine J, Raja R, Achenie L, Rosenberg DW. Genetic signatures of high- and low-risk aberrant crypt foci in a mouse model of sporadic colon cancer. Cancer Res. 2004 Sep 15; 64(18):6394-401. PMID: 15374946.
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    66. Dong M, Guda K, Nambiar PR, Nakanishi M, Lichtler AC, Nishikawa M, Giardina C, Rosenberg DW. Azoxymethane-induced pre-adipocyte factor 1 (Pref-1) functions as a differentiation inhibitor in colonic epithelial cells. Carcinogenesis. 2004 Nov; 25(11):2239-46. PMID: 15297369.
      View in: PubMed
    67. Taylor TB, Nambiar PR, Raja R, Cheung E, Rosenberg DW, Anderegg B. Microgenomics: Identification of new expression profiles via small and single-cell sample analyses. Cytometry A. 2004 Jun; 59(2):254-61. PMID: 15170605.
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    68. Guda K, Upender MB, Belinsky G, Flynn C, Nakanishi M, Marino JN, Ried T, Rosenberg DW. Carcinogen-induced colon tumors in mice are chromosomally stable and are characterized by low-level microsatellite instability. Oncogene. 2004 May 6; 23(21):3813-21. PMID: 15021908.
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    69. Ilsley JN, Belinsky GS, Guda K, Zhang Q, Huang X, Blumberg JB, Milbury PE, Roberts LJ, Stevens RG, Rosenberg DW. Dietary iron promotes azoxymethane-induced colon tumors in mice. Nutr Cancer. 2004; 49(2):162-9. PMID: 15489209.
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    70. Aizu W, Guda K, Nambiar P, Xin T, Thibodeau M, Rosenberg DW, Giardina C. p53 and its co-activator p300 are inversely regulated in the mouse colon in response to carcinogen. Toxicol Lett. 2003 Sep 30; 144(2):213-24. PMID: 12927365.
      View in: PubMed
    71. Rosenberg D, Groussin L, Jullian E, Perlemoine K, Medjane S, Louvel A, Bertagna X, Bertherat J. Transcription factor 3',5'-cyclic adenosine 5'-monophosphate-responsive element-binding protein (CREB) is decreased during human adrenal cortex tumorigenesis and fetal development. J Clin Endocrinol Metab. 2003 Aug; 88(8):3958-65. PMID: 12915693.
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    72. Flynn C, Levine J, Rosenberg DW. Murine models of ulcerative colitis. Arch Pharm Res. 2003 Jun; 26(6):433-40. PMID: 12877549.
      View in: PubMed
    73. Stevens RG, Morris JE, Cordis GA, Anderson LE, Rosenberg DW, Sasser LB. Oxidative damage in colon and mammary tissue of the HFE-knockout mouse. Free Radic Biol Med. 2003 May 1; 34(9):1212-6. PMID: 12706501.
      View in: PubMed
    74. Guda K, Claffey KP, Dong M, Nambiar PR, Rosenberg DW. Defective processing of the transforming growth factor-beta1 in azoxymethane-induced mouse colon tumors. Mol Carcinog. 2003 May; 37(1):51-9. PMID: 12720300.
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    75. Guda K, Cui H, Garg S, Dong M, Nambiar PR, Achenie LE, Rosenberg DW. Multistage gene expression profiling in a differentially susceptible mouse colon cancer model. Cancer Lett. 2003 Feb 28; 191(1):17-25. PMID: 12609705.
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    76. Dong M, Guda K, Nambiar PR, Rezaie A, Belinsky GS, Lambeau G, Giardina C, Rosenberg DW. Inverse association between phospholipase A2 and COX-2 expression during mouse colon tumorigenesis. Carcinogenesis. 2003 Feb; 24(2):307-15. PMID: 12584182.
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    77. Nambiar PR, Girnun G, Lillo NA, Guda K, Whiteley HE, Rosenberg DW. Preliminary analysis of azoxymethane induced colon tumors in inbred mice commonly used as transgenic/knockout progenitors. Int J Oncol. 2003 Jan; 22(1):145-50. PMID: 12469197.
      View in: PubMed
    78. DeAngelo AB, Geter DR, Rosenberg DW, Crary CK, George MH. The induction of aberrant crypt foci (ACF) in the colons of rats by trihalomethanes administered in the drinking water. Cancer Lett. 2002 Dec 10; 187(1-2):25-31. PMID: 12359347.
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    79. Rosenberg D, Groussin L, Bertagna X, Bertherat J. cAMP pathway alterations from the cell surface to the nucleus in adrenocortical tumors. Endocr Res. 2002 Nov; 28(4):765-75. PMID: 12530696.
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    80. Cui H, Dong M, Sadhu DN, Rosenberg DW. Suppression of kinesin expression disrupts adenomatous polyposis coli (APC) localization and affects beta-catenin turnover in young adult mouse colon (YAMC) epithelial cells. Exp Cell Res. 2002 Oct 15; 280(1):12-23. PMID: 12372335.
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    81. Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13771-6. PMID: 12370429; PMCID: PMC129773.
    82. Nambiar PR, Giardina C, Guda K, Aizu W, Raja R, Rosenberg DW. Role of the alternating reading frame (P19)-p53 pathway in an in vivo murine colon tumor model. Cancer Res. 2002 Jul 1; 62(13):3667-74. PMID: 12097273.
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    83. Guda K, Giardina C, Nambiar P, Cui H, Rosenberg DW. Aberrant transforming growth factor-beta signaling in azoxymethane-induced mouse colon tumors. Mol Carcinog. 2001 Aug; 31(4):204-13. PMID: 11536370.
      View in: PubMed
    84. Inan MS, Tolmacheva V, Wang QS, Rosenberg DW, Giardina C. Transcription factor NF-kappaB participates in regulation of epithelial cell turnover in the colon. Am J Physiol Gastrointest Liver Physiol. 2000 Dec; 279(6):G1282-91. PMID: 11093952.
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    85. Inan MS, Place R, Tolmacheva V, Wang QS, Hubbard AK, Rosenberg DW, Giardina C. IkappaBbeta-related proteins in normal and transformed colonic epithelial cells. Mol Carcinog. 2000 Sep; 29(1):25-36. PMID: 11020244.
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    86. Wang QS, Guda K, Papanikolaou A, Dong M, Rosenberg DW. Expression of transforming growth factor beta1 and its type II receptor in mouse colon tumors induced by azoxymethane. Int J Oncol. 2000 Sep; 17(3):551-8. PMID: 10938397.
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    87. Papanikolaou A, Wang QS, Papanikolaou D, Whiteley HE, Rosenberg DW. Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesis. Carcinogenesis. 2000 Aug; 21(8):1567-72. PMID: 10910960.
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    88. Wang QS, Papanikolaou A, Nambiar PR, Rosenberg DW. Differential expression of p16(INK4a) in azoxymethane-induced mouse colon tumorigenesis. Mol Carcinog. 2000 Jul; 28(3):139-47. PMID: 10942530.
      View in: PubMed
    89. Inan MS, Rasoulpour RJ, Yin L, Hubbard AK, Rosenberg DW, Giardina C. The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line. Gastroenterology. 2000 Apr; 118(4):724-34. PMID: 10734024.
      View in: PubMed
    90. Bolt AB, Papanikolaou A, Delker DA, Wang QS, Rosenberg DW. Azoxymethane induces KI-ras activation in the tumor resistant AKR/J mouse colon. Mol Carcinog. 2000 Mar; 27(3):210-8. PMID: 10708483.
      View in: PubMed
    91. Papanikolaou A, Wang QS, Mulherkar R, Bolt A, Rosenberg DW. Expression analysis of the group IIA secretory phospholipase A(2) in mice with differential susceptibility to azoxymethane-induced colon tumorigenesis. Carcinogenesis. 2000 Feb; 21(2):133-8. PMID: 10657948.
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    92. Delker DA, Papanikolaou A, Suhr YJ, Rosenberg DW. Diallyl sulfide enhances azoxymethane-induced preneoplasia in Fischer 344 rat colon. Chem Biol Interact. 2000 Feb 1; 124(3):149-60. PMID: 10728775.
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    93. Wang QS, Walsh A, Goldsby JS, Papanikolaou A, Bolt AB, Rosenberg DW. Preliminary analysis of azoxymethane-induced colon tumorigenesis in mouse aggregation chimeras. Carcinogenesis. 1999 Apr; 20(4):691-7. PMID: 10223201.
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    94. Delker DA, Wang QS, Papanikolaou A, Whiteley HE, Rosenberg DW. Quantitative assessment of azoxymethane-induced aberrant crypt foci in inbred mice. Exp Mol Pathol. 1999 Feb; 65(3):141-9. PMID: 10234360.
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    95. Chetboul V, Adam M, Deprez I, Ambriovic A, Rosenberg D, Crespeau F, Saana M, Pham I, Eloit M, Adnot S, Pouchelon JL. Expression of biologically active atrial natriuretic factor following intrahepatic injection of a replication-defective adenoviral vector in dogs. Hum Gene Ther. 1999 Jan 20; 10(2):281-90. PMID: 10022552.
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    96. Wang QS, Papanikolaou A, Sabourin CL, Rosenberg DW. Altered expression of cyclin D1 and cyclin-dependent kinase 4 in azoxymethane-induced mouse colon tumorigenesis. Carcinogenesis. 1998 Nov; 19(11):2001-6. PMID: 9855016.
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    97. Delker DA, McKnight SJ, Rosenberg DW. The role of alcohol dehydrogenase in the metabolism of the colon carcinogen methylazoxymethanol. Toxicol Sci. 1998 Sep; 45(1):66-71. PMID: 9848112.
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    98. Papanikolaou A, Wang QS, Delker DA, Rosenberg DW. Azoxymethane-induced colon tumors and aberrant crypt foci in mice of different genetic susceptibility. Cancer Lett. 1998 Aug 14; 130(1-2):29-34. PMID: 9751253.
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    99. Papanikolaou A, Shank RC, Delker DA, Povey A, Cooper DP, Rosenberg DW. Initial levels of azoxymethane-induced DNA methyl adducts are not predictive of tumor susceptibility in inbred mice. Toxicol Appl Pharmacol. 1998 May; 150(1):196-203. PMID: 9630469.
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    100. Delker DA, Bammler TK, Rosenberg DW. A comparative study of hepatic and colonic metabolic enzymes in inbred mouse lines before and after treatment with the colon carcinogen, 1,2-dimethylhydrazine. Drug Metab Dispos. 1996 Apr; 24(4):408-13. PMID: 8801055.
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    101. Rosenberg DW. Non-homogeneous marking of distal colonic mucosa using Dolichos biflorus lectin. Cancer Lett. 1995 Nov 27; 98(1):33-7. PMID: 8529203.
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    102. Rosenberg DW, Drummond GS, Smith TJ. Depletion of cytochrome P-450 by thyroid hormone and cobalt-protoporphyrin IX in rat liver: evidence that susceptibility varies among forms of the heme protein. Pharmacology. 1995 Oct; 51(4):254-62. PMID: 8577819.
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    103. Rosenberg DW, Liu Y. Induction of aberrant crypts in murine colon with varying sensitivity to colon carcinogenesis. Cancer Lett. 1995 Jun 8; 92(2):209-14. PMID: 7600532.
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    104. Park BC, Liu Y, Averill DR, Jackman MI, Rosenberg DW. Cytochemical localization of the acetone-inducible cytochrome P-450 isoform, CYP2E1, in murine colonic epithelium. Pharmacology. 1995 Jun; 50(6):339-47. PMID: 7568332.
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    105. Rosenberg DW, Kappas A. The comparative abilities of inorganic cobalt and cobalt-protoporphyrin to affect copper metabolism and elevate plasma ceruloplasmin. Pharmacology. 1995 Mar; 50(3):201-8. PMID: 7746837.
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    106. Shachter NS, Hayek T, Leff T, Smith JD, Rosenberg DW, Walsh A, Ramakrishnan R, Goldberg IJ, Ginsberg HN, Breslow JL. Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice. J Clin Invest. 1994 Apr; 93(4):1683-90. PMID: 8163669; PMCID: PMC294216.
    107. Rosenberg DW, Mankowski DC. Induction of cyp2e-1 protein in mouse colon. Carcinogenesis. 1994 Jan; 15(1):73-8. PMID: 8293551.
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    108. Rosenberg DW. Pharmacokinetics of cobalt chloride and cobalt-protoporphyrin. Drug Metab Dispos. 1993 Sep-Oct; 21(5):846-9. PMID: 7902247.
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    109. Rosenberg DW, Leff T. Regulation of cytochrome P450 in cultured human colonic cells. Arch Biochem Biophys. 1993 Jan; 300(1):186-92. PMID: 8380963.
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    110. Michnovicz JJ, Rosenberg DW. Oxidative metabolism of estrogens in rat intestinal mitochondria. Biochem Pharmacol. 1992 Apr 15; 43(8):1847-52. PMID: 1575777.
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    111. Drummond GS, Rosenberg DW, Kappas A. Intestinal heme oxygenase inhibition and increased biliary iron excretion by metalloporphyrins. Gastroenterology. 1992 Apr; 102(4 Pt 1):1170-5. PMID: 1551526.
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    112. Albers R, Rosenberg DW. In vivo intestinal metabolism of 7-ethoxycoumarin in the rat: production and distribution of phase I and II metabolites in the isolated, perfused intestinal loop. Toxicol Appl Pharmacol. 1991 Jul; 109(3):507-13. PMID: 1853348.
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    113. Rosenberg DW, Kappas A. Induction of heme oxygenase in the small intestinal epithelium: a response to oral cadmium exposure. Toxicology. 1991 Apr 8; 67(2):199-210. PMID: 2031253.
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    114. Rosenberg DW. Tissue-specific induction of the carcinogen inducible cytochrome P450 isoform, P450IAI, in colonic epithelium. Arch Biochem Biophys. 1991 Jan; 284(1):223-6. PMID: 1989500.
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    115. Rosenberg DW. Dietary modulation of cytochrome P450 in the small intestinal epithelium. Pharmacology. 1991; 43(1):36-46. PMID: 1961769.
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    116. Rosenberg DW, Roque H, Kappas A. A fluorometric method for measuring ethoxycoumarin O-deethylase activity by reversed-phase high performance liquid chromatography. Anal Biochem. 1990 Dec; 191(2):354-8. PMID: 2085179.
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    117. Rosenberg DW, Kappas A. Characterization of heme oxygenase in the small intestinal epithelium. Arch Biochem Biophys. 1989 Nov 1; 274(2):471-80. PMID: 2802622.
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    118. Rosenberg DW, Kappas A. Trace metal interactions in vivo: inorganic cobalt enhances urinary copper excretion without producing an associated zincuresis in rats. J Nutr. 1989 Sep; 119(9):1259-68. PMID: 2795240.
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    119. Rosenberg DW, Kappas A. Actions of orally administered organotin compounds on heme metabolism and cytochrome P-450 content and function in intestinal epithelium. Biochem Pharmacol. 1989 Apr 1; 38(7):1155-61. PMID: 2706014.
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    120. Drummond GS, Rosenberg DW, Kihlström-Johanson AC, Kappas A. Effects of tin-porphyrins on developmental changes in hepatic cytochrome P450 content, selected P450-dependent drug-metabolizing enzyme activities and brain glutathione levels in the newborn rat. Pharmacology. 1989; 39(5):273-84. PMID: 2616631.
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    121. Rosenberg DW, Kappas A. Comparative ability of exogenously administered metals to alter tissue levels and urinary output of copper and zinc. Pharmacology. 1989; 38(3):159-66. PMID: 2727054.
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    122. Rosenberg DW, Drummond GS, Kappas A. The in vitro and in vivo inhibition of intestinal heme oxygenase by tin-protoporphyrin. Pharmacology. 1989; 39(4):224-9. PMID: 2608721.
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    123. Rosenberg DW, Sardana MK, Kappas A. Altered induction response of hepatic cytochrome P-450 to phenobarbital, 3-methylcholanthrene, and beta-naphthoflavone in organotin-treated animals. Biochem Pharmacol. 1985 Apr 1; 34(7):997-1005. PMID: 3986002.
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    124. Rosenberg DW, Anderson KE, Kappas A. The potent induction of intestinal heme oxygenase by the organotin compound, bis(tri-n-butyltin)oxide. Biochem Biophys Res Commun. 1984 Mar 30; 119(3):1022-7. PMID: 6546875.
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    125. Rosenberg DW, Drummond GS. Direct in vitro effects of bis(tri-n-butyltin)oxide on hepatic cytochrome P-450. Biochem Pharmacol. 1983 Dec 15; 32(24):3823-9. PMID: 6661254.
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    126. Drummond GS, Rosenberg DW, Kappas A. Metal induction of haem oxygenase without concurrent degradation of cytochrome P-450. Protective effects of compound SKF 525A on the haem protein. Biochem J. 1982 Jan 15; 202(1):59-66. PMID: 6896277; PMCID: PMC1158074.
    127. Rosenberg DW, Drummond GS, Kappas A. The influence of organometals on heme metabolism. In vivo and in vitro studies with organotins. Mol Pharmacol. 1982 Jan; 21(1):150-8. PMID: 6897100.
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    128. Rosenberg DW, Drummond GS, Cornish HC, Kappas A. Prolonged induction of hepatic haem oxygenase and decreases in cytochrome P-450 content by organotin compounds. Biochem J. 1980 Aug 15; 190(2):465-8. PMID: 6894090; PMCID: PMC1162114.
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