Last Name

Blanka Rogina PhD

TitleAssociate Professor
InstitutionUConn Health Center
DepartmentGenetics and Developmental Biology
AddressMC 6403
Cell and Genome Sciences Building, MC 6403
400 Farmington Avenue
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Frankel S, Woods J, Ziafazeli T, Rogina B. RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity. Aging (Albany NY). 2015 Dec; 7(12):1112-29. PMID: 26647291.
      View in: PubMed
    2. Rogers RP, Rogina B. The role of INDY in metabolism, health and longevity. Front Genet. 2015; 6:204. PMID: 26106407; PMCID: PMC4460575.
    3. Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VN, Huang TH, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, Orentreich N. The first international mini-symposium on methionine restriction and lifespan. Front Genet. 2014; 5:122. PMID: 24847356; PMCID: PMC4023024.
    4. Woods JK, Kowalski S, Rogina B. Determination of the spontaneous locomotor activity in Drosophila melanogaster. J Vis Exp. 2014; (86). PMID: 24747955.
      View in: PubMed
    5. Rogers RP, Rogina B. Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies. Aging (Albany NY). 2014 Apr; 6(4):335-50. PMID: 24827528; PMCID: PMC4032799.
    6. Rogina B, Helfand SL. Indy mutations and Drosophila longevity. Front Genet. 2013; 4:47. PMID: 23580130; PMCID: PMC3619052.
    7. Rogers RP, Rogina B. A gutsy way to extend longevity. Front Genet. 2012; 3:108. PMID: 22707956; PMCID: PMC3374461.
    8. Anisimov VN, Bartke A, Barzilai N, Batin MA, Blagosklonny MV, Brown-Borg H, Budovskaya Y, Campisi J, Friguet B, Fraifeld V, Franceschi C, Gems D, Gladyshev V, Gorbunova V, Gudkov AV, Kennedy B, Konovalenko M, Kraemer B, Moskalev A, Petropoulos I, Pasyukova E, Rattan S, Rogina B, Seluanov A, Shaposhnikov M, Shmookler Reis R, Tavernarakis N, Vijg J, Yashin A, Zimniak P. The second international conference "genetics of aging and longevity". Aging (Albany NY). 2012 May; 4(5):305-17. PMID: 22661237.
      View in: PubMed
    9. Frankel S, Rogina B. Indy mutants: live long and prosper. Front Genet. 2012; 3:13. PMID: 22363340; PMCID: PMC3281209.
    10. Garber G, Smith LA, Reenan RA, Rogina B. Effect of sodium channel abundance on Drosophila development, reproductive capacity and aging. Fly (Austin). 2012 Jan-Mar; 6(1):57-67. PMID: 22513411; PMCID: PMC3365838.
    11. Rogina B. A grand challenge for genetics of aging: adding healthy years to our lives. Front Genet. 2011; 2:79. PMID: 22303373; PMCID: PMC3268632.
    12. Rogina B. For the special issue: aging studies in Drosophila melanogaster. Exp Gerontol. 2011 May; 46(5):317-9. PMID: 20828603; PMCID: PMC3008287.
    13. Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, McBurney M, Nabeshima Y, Neri C, Oberdoerffer P, Pestell RG, Rogina B, Sadoshima J, Sartorelli V, Serrano M, Sinclair DA, Steegborn C, Tatar M, Tissenbaum HA, Tong Q, Tsubota K, Vaquero A, Verdin E. Dietary restriction: standing up for sirtuins. Science. 2010 Aug 27; 329(5995):1012-3; author reply 1013-4. PMID: 20798296; PMCID: PMC3985480.
    14. Frankel S, Ziafazeli T, Rogina B. dSir2 and longevity in Drosophila. Exp Gerontol. 2011 May; 46(5):391-6. PMID: 20728527; PMCID: PMC2997167.
    15. Parashar V, Rogina B. dSir2 and fly mobility. Cell Cycle. 2010 Feb 1; 9(3):433. PMID: 20107322; PMCID: PMC2911946.
    16. Rogina B. The effect of sex peptide and calorie intake on fecundity in female Drosophila melanogaster. ScientificWorldJournal. 2009; 9:1178-89. PMID: 19838603; PMCID: PMC2917383.
    17. Parashar V, Rogina B. dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction. Aging (Albany NY). 2009 Jun; 1(6):529-41. PMID: 20157536; PMCID: PMC2806034.
    18. Wang PY, Neretti N, Whitaker R, Hosier S, Chang C, Lu D, Rogina B, Helfand SL. Long-lived Indy and calorie restriction interact to extend life span. Proc Natl Acad Sci U S A. 2009 Jun 9; 106(23):9262-7. PMID: 19470468; PMCID: PMC2685744.
    19. Neretti N, Wang PY, Brodsky AS, Nyguyen HH, White KP, Rogina B, Helfand SL. Long-lived Indy induces reduced mitochondrial reactive oxygen species production and oxidative damage. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2277-82. PMID: 19164521; PMCID: PMC2629441.
    20. Parashar V, Frankel S, Lurie AG, Rogina B. The effects of age on radiation resistance and oxidative stress in adult Drosophila melanogaster. Radiat Res. 2008 Jun; 169(6):707-11. PMID: 18494545.
      View in: PubMed
    21. Reenan RA, Rogina B. Acquired temperature-sensitive paralysis as a biomarker of declining neuronal function in aging Drosophila. Aging Cell. 2008 Mar; 7(2):179-86. PMID: 18208580.
      View in: PubMed
    22. Rogina B, Wolverton T, Bross TG, Chen K, Müller HG, Carey JR. Distinct biological epochs in the reproductive life of female Drosophila melanogaster. Mech Ageing Dev. 2007 Sep; 128(9):477-85. PMID: 17681363; PMCID: PMC2213252.
    23. Stipcevic M, Rogina BM. Quantum random number generator based on photonic emission in semiconductors. Rev Sci Instrum. 2007 Apr; 78(4):045104. PMID: 17477690.
      View in: PubMed
    24. Knauf F, Mohebbi N, Teichert C, Herold D, Rogina B, Helfand S, Gollasch M, Luft FC, Aronson PS. The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates. Biochem J. 2006 Jul 1; 397(1):25-9. PMID: 16608441; PMCID: PMC1479758.
    25. Bross TG, Rogina B, Helfand SL. Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction. Aging Cell. 2005 Dec; 4(6):309-17. PMID: 16300483.
      View in: PubMed
    26. Frankel S, Rogina B. Sir2, caloric restriction and aging. Pathol Biol (Paris). 2006 Mar; 54(2):55-7. PMID: 15935564.
      View in: PubMed
    27. Frankel S, Rogina B. Drosophila longevity is not affected by heterochromatin-mediated gene silencing. Aging Cell. 2005 Feb; 4(1):53-6. PMID: 15659213.
      View in: PubMed
    28. Rogina B, Helfand SL. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci U S A. 2004 Nov 9; 101(45):15998-6003. PMID: 15520384; PMCID: PMC528752.
    29. Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature. 2004 Aug 5; 430(7000):686-9. PMID: 15254550.
      View in: PubMed
    30. Marden JH, Rogina B, Montooth KL, Helfand SL. Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3369-73. PMID: 12626742; PMCID: PMC152299.
    31. Helfand SL, Rogina B. Molecular genetics of aging in the fly: is this the end of the beginning? Bioessays. 2003 Feb; 25(2):134-41. PMID: 12539239.
      View in: PubMed
    32. Helfand SL, Rogina B. From genes to aging in Drosophila. Adv Genet. 2003; 49:67-109. PMID: 12779251.
      View in: PubMed
    33. Helfand SL, Rogina B. Genetics of aging in the fruit fly, Drosophila melanogaster. Annu Rev Genet. 2003; 37:329-48. PMID: 14616064.
      View in: PubMed
    34. Rogina B, Helfand SL, Frankel S. Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science. 2002 Nov 29; 298(5599):1745. PMID: 12459580.
      View in: PubMed
    35. Knauf F, Rogina B, Jiang Z, Aronson PS, Helfand SL. Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy. Proc Natl Acad Sci U S A. 2002 Oct 29; 99(22):14315-9. PMID: 12391301; PMCID: PMC137881.
    36. Pan ZZ, Kronenberg MS, Huang DY, Sumoy L, Rogina B, Lichtler AC, Upholt WB. MSX2 expression in the apical ectoderm ridge is regulated by an MSX2 and Dlx5 binding site. Biochem Biophys Res Commun. 2002 Jan 25; 290(3):955-61. PMID: 11798166.
      View in: PubMed
    37. Rogina B, Reenan RA, Nilsen SP, Helfand SL. Extended life-span conferred by cotransporter gene mutations in Drosophila. Science. 2000 Dec 15; 290(5499):2137-40. PMID: 11118146.
      View in: PubMed
    38. Rogina B, Helfand SL. Cu, Zn superoxide dismutase deficiency accelerates the time course of an age-related marker in Drosophila melanogaster. Biogerontology. 2000; 1(2):163-9. PMID: 11707932.
      View in: PubMed
    39. Helfand SL, Rogina B. Regulation of gene expression during aging. Results Probl Cell Differ. 2000; 29:67-80. PMID: 10838695.
      View in: PubMed
    40. Rogina B, Vaupel JW, Partridge L, Helfand SL. Regulation of gene expression is preserved in aging Drosophila melanogaster. Curr Biol. 1998 Apr 9; 8(8):475-8. PMID: 9550706.
      View in: PubMed
    41. Rogina B. Patterns of expression of Hoxa-11 in micromass cultures of chick limb mesenchyme from various stages suggest a role for Hoxa-11 in the specification of the zeugopod. Biochem Mol Biol Int. 1997 Jul; 42(3):583-9. PMID: 9247716.
      View in: PubMed
    42. Rogina B, Benzer S, Helfand SL. Drosophila drop-dead mutations accelerate the time course of age-related markers. Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12):6303-6. PMID: 9177212; PMCID: PMC21044.
    43. Rogina B, Helfand SL. Spatial and temporal pattern of expression of the wingless and engrailed genes in the adult antenna is regulated by age-dependent mechanisms. Mech Dev. 1997 Apr; 63(1):89-97. PMID: 9178259.
      View in: PubMed
    44. Rogina B, Helfand SL. Timing of expression of a gene in the adult Drosophila is regulated by mechanisms independent of temperature and metabolic rate. Genetics. 1996 Aug; 143(4):1643-51. PMID: 8844152; PMCID: PMC1207427.
    45. Rogina B, Helfand SL. Regulation of gene expression is linked to life span in adult Drosophila. Genetics. 1995 Nov; 141(3):1043-8. PMID: 8582611; PMCID: PMC1206828.
    46. Blake KJ, Rogina B, Centurion A, Helfand SL. Changes in gene expression during post-eclosional development in the olfactory system of Drosophila melanogaster. Mech Dev. 1995 Aug; 52(2-3):179-85. PMID: 8541207.
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    47. Helfand SL, Blake KJ, Rogina B, Stracks MD, Centurion A, Naprta B. Temporal patterns of gene expression in the antenna of the adult Drosophila melanogaster. Genetics. 1995 Jun; 140(2):549-55. PMID: 7498736; PMCID: PMC1206634.
    48. Rogina B, Upholt WB. The chicken homeobox gene Hoxd-11 encodes two alternatively spliced RNA species. Biochem Mol Biol Int. 1995 Apr; 35(4):825-31. PMID: 7542959.
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    49. Rogina B, Upholt WB. Cloning of full coding chicken cDNAs for the homeobox-containing gene Hoxd-13. Nucleic Acids Res. 1993 Mar 11; 21(5):1316. PMID: 8096637; PMCID: PMC309299.
    50. Coelho CN, Sumoy L, Rogina B, Upholt WB, Kosher RA. Roles of the chicken homeobox-containing genes GHox-8, GHox-7, and GHox-4.6 in pattern formation during limb development. Prog Clin Biol Res. 1993; 383A:61-70. PMID: 7905642.
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    51. Rogina B, Coelho CN, Kosher RA, Upholt WB. The pattern of expression of the chicken homolog of HOX1I in the developing limb suggests a possible role in the ectodermal inhibition of chondrogenesis. Dev Dyn. 1992 Jan; 193(1):92-101. PMID: 1347239.
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