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Last Name
Institution

Janet E McElhaney MD

TitleAssociate Professor
InstitutionUConn Health Center
DepartmentImmunology
AddressMC 1601
MC 1601
263 Farmington Avenue
Phone860-679-4444
Fax860-679-7905
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. McElhaney JE, Kuchel GA, Zhou X, Swain SL, Haynes L. T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines. Front Immunol. 2016; 7:41. PMID: 26941738.
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    2. Mosterín Höpping A, McElhaney J, Fonville JM, Powers DC, Beyer WE, Smith DJ. The confounded effects of age and exposure history in response to influenza vaccination. Vaccine. 2016 Jan 20; 34(4):540-6. PMID: 26667611.
      View in: PubMed
    3. McElhaney JE, Garneau H, Camous X, Dupuis G, Pawelec G, Baehl S, Tessier D, Frost EH, Frasca D, Larbi A, Fulop T. Predictors of the antibody response to influenza vaccination in older adults with type 2 diabetes. BMJ Open Diabetes Res Care. 2015; 3(1):e000140. PMID: 26504526; PMCID: PMC4611872.
    4. Vasunilashorn SM, Ngo L, Inouye SK, Libermann TA, Jones RN, Alsop DC, Guess J, Jastrzebski S, McElhaney JE, Kuchel GA, Marcantonio ER. Cytokines and Postoperative Delirium in Older Patients Undergoing Major Elective Surgery. J Gerontol A Biol Sci Med Sci. 2015 Oct; 70(10):1289-95. PMID: 26215633.
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    5. Fulop T, McElhaney J, Pawelec G, Cohen AA, Morais JA, Dupuis G, Baehl S, Camous X, Witkowski JM, Larbi A. Frailty, Inflammation and Immunosenescence. Interdiscip Top Gerontol Geriatr. 2015; 41:26-40. PMID: 26301977.
      View in: PubMed
    6. Briggs MC, McElhaney JE. Frailty and Interprofessional Collaboration. Interdiscip Top Gerontol Geriatr. 2015; 41:121-36. PMID: 26301985.
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    7. Benoit A, Beran J, Devaster JM, Esen M, Launay O, Leroux-Roels G, McElhaney JE, Oostvogels L, van Essen GA, Gaglani M, Jackson LA, Vesikari T, Legrand C, Tibaldi F, Innis BL, Dewé W. Hemagglutination Inhibition Antibody Titers as a Correlate of Protection Against Seasonal A/H3N2 Influenza Disease. Open Forum Infect Dis. 2015 Apr; 2(2):ofv067. PMID: 26180823; PMCID: PMC4498268.
    8. Lal H, Cunningham AL, Godeaux O, Chlibek R, Diez-Domingo J, Hwang SJ, Levin MJ, McElhaney JE, Poder A, Puig-Barberà J, Vesikari T, Watanabe D, Weckx L, Zahaf T, Heineman TC. Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. N Engl J Med. 2015 May 28; 372(22):2087-96. PMID: 25916341.
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    9. McNeil SA, Andrew MK, Ye L, Haguinet F, Hatchette TF, ElSherif M, LeBlanc J, Ambrose A, McGeer A, McElhaney JE, Loeb M, MacKinnon-Cameron D, Sharma R, Dos Santos G, Shinde V. Interim estimates of 2014/15 influenza vaccine effectiveness in preventing laboratory-confirmed influenza-related hospitalisation from the Serious Outcomes Surveillance Network of the Canadian Immunization Research Network, January 2015. Euro Surveill. 2015; 20(5):21024. PMID: 25677052.
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    10. McElhaney JE, Gentleman B. Cell-Mediated Immune Response to Influenza Using Ex Vivo Stimulation and Assays of Cytokine and Granzyme B Responses. Methods Mol Biol. 2015; 1343:121-41. PMID: 26420714.
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    11. Vahedi F, Fraleigh N, Vlasschaert C, McElhaney J, Hanifi-Moghaddam P. Human granzymes: related but far apart. Med Hypotheses. 2014 Dec; 83(6):688-93. PMID: 25459135.
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    12. Johnstone J, Parsons R, Botelho F, Millar J, McNeil S, Fulop T, McElhaney J, Andrew MK, Walter SD, Devereaux PJ, Malekesmaeili M, Brinkman RR, Mahony J, Bramson J, Loeb M. Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents. PLoS One. 2014; 9(9):e108481. PMID: 25275464; PMCID: PMC4183538.
    13. Derhovanessian E, Maier AB, Hähnel K, McElhaney JE, Slagboom EP, Pawelec G. Latent infection with cytomegalovirus is associated with poor memory CD4 responses to influenza A core proteins in the elderly. J Immunol. 2014 Oct 1; 193(7):3624-31. PMID: 25187662.
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    14. Dill J, Unson C, Kenyon-Pesce L, Kuchel GA, McElhaney J. Recruitment and retention of healthy and high-risk older adults for a multiyear influenza vaccination study. Conn Med. 2014 Sep; 78(8):481-6. PMID: 25314888.
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    15. Haq K, McElhaney JE. Ageing and respiratory infections: the airway of ageing. Immunol Lett. 2014 Nov; 162(1 Pt B):323-8. PMID: 24973652.
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    16. Beyer WE, McElhaney J, Smith DJ, Monto AS, Nguyen-Van-Tam JS, Osterhaus AD. Reply: Letter to the editor, Cochrane rearranged. Vaccine. 2015 Jan 1; 33(1):13-4. PMID: 24852718.
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    17. Schneeberg A, Bettinger JA, McNeil S, Ward BJ, Dionne M, Cooper C, Coleman B, Loeb M, Rubinstein E, McElhaney J, Scheifele DW, Halperin SA. Knowledge, attitudes, beliefs and behaviours of older adults about pneumococcal immunization, a Public Health Agency of Canada/Canadian Institutes of Health Research Influenza Research Network (PCIRN) investigation. BMC Public Health. 2014; 14:442. PMID: 24884433; PMCID: PMC4046143.
    18. Haq K, McElhaney JE. Immunosenescence: Influenza vaccination and the elderly. Curr Opin Immunol. 2014 Aug; 29:38-42. PMID: 24769424.
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    19. van Essen GA, Beran J, Devaster JM, Durand C, Duval X, Esen M, Falsey AR, Feldman G, Gervais P, Innis BL, Kovac M, Launay O, Leroux-Roels G, McElhaney JE, McNeil S, Oujaa M, Richardus JH, Ruiz-Palacios G, Osborne RH, Oostvogels L. Influenza symptoms and their impact on elderly adults: randomised trial of AS03-adjuvanted or non-adjuvanted inactivated trivalent seasonal influenza vaccines. Influenza Other Respir Viruses. 2014 Jul; 8(4):452-62. PMID: 24702710; PMCID: PMC4181805.
    20. McNeil S, Shinde V, Andrew M, Hatchette T, Leblanc J, Ambrose A, Boivin G, Bowie W, Diaz-Mitoma F, Elsherif M, Green K, Haguinet F, Halperin S, Ibarguchi B, Katz K, Langley J, Lagace-Wiens P, Light B, Loeb M, McElhaney J, Mackinnon-Cameron D, McCarthy A, Poirier M, Powis J, Richardson D, Semret M, Smith S, Smyth D, Stiver G, Trottier S, Valiquette L, Webster D, Ye L, McGeer A. Interim estimates of 2013/14 influenza clinical severity and vaccine effectiveness in the prevention of laboratory-confirmed influenza-related hospitalisation, Canada, February 2014. Euro Surveill. 2014; 19(9). PMID: 24626207.
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    21. Falsey AR, McElhaney JE, Beran J, van Essen GA, Duval X, Esen M, Galtier F, Gervais P, Hwang SJ, Kremsner P, Launay O, Leroux-Roels G, McNeil SA, Nowakowski A, Richardus JH, Ruiz-Palacios G, St Rose S, Devaster JM, Oostvogels L, Durviaux S, Taylor S. Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness. J Infect Dis. 2014 Jun 15; 209(12):1873-81. PMID: 24482398; PMCID: PMC4038137.
    22. Durviaux S, Treanor J, Beran J, Duval X, Esen M, Feldman G, Frey SE, Launay O, Leroux-Roels G, McElhaney JE, Nowakowski A, Ruiz-Palacios GM, van Essen GA, Oostvogels L, Devaster JM, Walravens K. Genetic and antigenic typing of seasonal influenza virus breakthrough cases from a 2008-2009 vaccine efficacy trial. Clin Vaccine Immunol. 2014 Mar; 21(3):271-9. PMID: 24371255; PMCID: PMC3957665.
    23. McElhaney J, Osterhaus A. Third European Influenza Summit: organized by the European Scientific Working group on Influenza (ESWI). Vaccine. 2013 Dec 16; 31(52):6161-7. PMID: 24183711.
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    24. Beyer WE, McElhaney J, Smith DJ, Monto AS, Nguyen-Van-Tam JS, Osterhaus AD. Cochrane re-arranged: support for policies to vaccinate elderly people against influenza. Vaccine. 2013 Dec 5; 31(50):6030-3. PMID: 24095882.
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    25. Scheifele DW, McNeil SA, Ward BJ, Dionne M, Cooper C, Coleman B, Loeb M, Rubinstein E, McElhaney J, Hatchette T, Li Y, Montomoli E, Schneeberg A, Bettinger JA, Halperin SA. Safety, immunogenicity, and tolerability of three influenza vaccines in older adults: results of a randomized, controlled comparison. Hum Vaccin Immunother. 2013 Nov; 9(11):2460-73. PMID: 23839537; PMCID: PMC3981857.
    26. McElhaney JE, Coler RN, Baldwin SL. Immunologic correlates of protection and potential role for adjuvants to improve influenza vaccines in older adults. Expert Rev Vaccines. 2013 Jul; 12(7):759-66. PMID: 23885821.
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    27. McElhaney JE, Beran J, Devaster JM, Esen M, Launay O, Leroux-Roels G, Ruiz-Palacios GM, van Essen GA, Caplanusi A, Claeys C, Durand C, Duval X, El Idrissi M, Falsey AR, Feldman G, Frey SE, Galtier F, Hwang SJ, Innis BL, Kovac M, Kremsner P, McNeil S, Nowakowski A, Richardus JH, Trofa A, Oostvogels L. AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial. Lancet Infect Dis. 2013 Jun; 13(6):485-96. PMID: 23518156.
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    28. Howcroft TK, Campisi J, Louis GB, Smith MT, Wise B, Wyss-Coray T, Augustine AD, McElhaney JE, Kohanski R, Sierra F. The role of inflammation in age-related disease. Aging (Albany NY). 2013 Jan; 5(1):84-93. PMID: 23474627; PMCID: PMC3616233.
    29. Solana R, Tarazona R, Aiello AE, Akbar AN, Appay V, Beswick M, Bosch JA, Campos C, Cantisán S, Cicin-Sain L, Derhovanessian E, Ferrando-Martínez S, Frasca D, Fulöp T, Govind S, Grubeck-Loebenstein B, Hill A, Hurme M, Kern F, Larbi A, López-Botet M, Maier AB, McElhaney JE, Moss P, Naumova E, Nikolich-Zugich J, Pera A, Rector JL, Riddell N, Sanchez-Correa B, Sansoni P, Sauce D, van Lier R, Wang GC, Wills MR, Zielinski M, Pawelec G. CMV and Immunosenescence: from basics to clinics. Immun Ageing. 2012; 9(1):23. PMID: 23114110; PMCID: PMC3585851.
    30. Thomas-Crusells J, McElhaney JE, Aguado MT. Report of the ad-hoc consultation on aging and immunization for a future WHO research agenda on life-course immunization. Vaccine. 2012 Sep 14; 30(42):6007-12. PMID: 22835737.
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    31. Pawelec G, McElhaney JE, Aiello AE, Derhovanessian E. The impact of CMV infection on survival in older humans. Curr Opin Immunol. 2012 Aug; 24(4):507-11. PMID: 22541724.
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    32. McElhaney JE, Zhou X, Talbot HK, Soethout E, Bleackley RC, Granville DJ, Pawelec G. The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines. Vaccine. 2012 Mar 9; 30(12):2060-7. PMID: 22289511; PMCID: PMC3345132.
    33. Behzad H, Huckriede AL, Haynes L, Gentleman B, Coyle K, Wilschut JC, Kollmann TR, Reed SG, McElhaney JE. GLA-SE, a synthetic toll-like receptor 4 agonist, enhances T-cell responses to influenza vaccine in older adults. J Infect Dis. 2012 Feb 1; 205(3):466-73. PMID: 22147791; PMCID: PMC3256953.
    34. Marcelin G, DuBois R, Rubrum A, Russell CJ, McElhaney JE, Webby RJ. A contributing role for anti-neuraminidase antibodies on immunity to pandemic H1N1 2009 influenza A virus. PLoS One. 2011; 6(10):e26335. PMID: 22039464; PMCID: PMC3200314.
    35. Shapiro M, Kvern B, Watson P, Guenther L, McElhaney J, McGeer A. Update on herpes zoster vaccination: a family practitioner's guide. Can Fam Physician. 2011 Oct; 57(10):1127-31. PMID: 21998225; PMCID: PMC3192074.
    36. Wang DJ, Boltz DA, McElhaney J, McCullers JA, Webby RJ, Webster RG. No evidence of a link between influenza vaccines and Guillain-Barre syndrome-associated antiganglioside antibodies. Influenza Other Respir Viruses. 2012 May; 6(3):159-66. PMID: 21955390; PMCID: PMC3595170.
    37. Wagar LE, Gentleman B, Pircher H, McElhaney JE, Watts TH. Influenza-specific T cells from older people are enriched in the late effector subset and their presence inversely correlates with vaccine response. PLoS One. 2011; 6(8):e23698. PMID: 21887299; PMCID: PMC3161762.
    38. McElhaney JE, Simor AE, McNeil S, Predy GN. Efficacy and Safety of CVT-E002, a Proprietary Extract of Panax quinquefolius in the Prevention of Respiratory Infections in Influenza-Vaccinated Community-Dwelling Adults: A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Trial. Influenza Res Treat. 2011; 2011:759051. PMID: 23074661; PMCID: PMC3447298.
    39. Zhou X, McElhaney JE. Age-related changes in memory and effector T cells responding to influenza A/H3N2 and pandemic A/H1N1 strains in humans. Vaccine. 2011 Mar 3; 29(11):2169-77. PMID: 21353149; PMCID: PMC3057414.
    40. Skowronski DM, Hottes TS, McElhaney JE, Janjua NZ, Sabaiduc S, Chan T, Gentleman B, Purych D, Gardy J, Patrick DM, Brunham RC, De Serres G, Petric M. Immuno-epidemiologic correlates of pandemic H1N1 surveillance observations: higher antibody and lower cell-mediated immune responses with advanced age. J Infect Dis. 2011 Jan 15; 203(2):158-67. PMID: 21288814; PMCID: PMC3071066.
    41. McElhaney JE. Influenza vaccine responses in older adults. Ageing Res Rev. 2011 Jul; 10(3):379-88. PMID: 21055484; PMCID: PMC3061971.
    42. Marcelin G, Bland HM, Negovetich NJ, Sandbulte MR, Ellebedy AH, Webb AD, Griffin YS, DeBeauchamp JL, McElhaney JE, Webby RJ. Inactivated seasonal influenza vaccines increase serum antibodies to the neuraminidase of pandemic influenza A(H1N1) 2009 virus in an age-dependent manner. J Infect Dis. 2010 Dec 1; 202(11):1634-8. PMID: 20979454; PMCID: PMC2974032.
    43. Skowronski DM, Hottes TS, Janjua NZ, Purych D, Sabaiduc S, Chan T, De Serres G, Gardy J, McElhaney JE, Patrick DM, Petric M. Prevalence of seroprotection against the pandemic (H1N1) virus after the 2009 pandemic. CMAJ. 2010 Nov 23; 182(17):1851-6. PMID: 20956500; PMCID: PMC2988533.
    44. Zhou X, Fragala MS, McElhaney JE, Kuchel GA. Conceptual and methodological issues relevant to cytokine and inflammatory marker measurements in clinical research. Curr Opin Clin Nutr Metab Care. 2010 Sep; 13(5):541-7. PMID: 20657280; PMCID: PMC2955626.
    45. Shahid Z, Kleppinger A, Gentleman B, Falsey AR, McElhaney JE. Clinical and immunologic predictors of influenza illness among vaccinated older adults. Vaccine. 2010 Aug 31; 28(38):6145-51. PMID: 20646987; PMCID: PMC2948951.
    46. Fulop T, Larbi A, Witkowski JM, McElhaney J, Loeb M, Mitnitski A, Pawelec G. Aging, frailty and age-related diseases. Biogerontology. 2010 Oct; 11(5):547-63. PMID: 20559726.
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    47. Boon AC, deBeauchamp J, Krauss S, Rubrum A, Webb AD, Webster RG, McElhaney J, Webby RJ. Cross-reactive neutralizing antibodies directed against pandemic H1N1 2009 virus are protective in a highly sensitive DBA/2 mouse influenza model. J Virol. 2010 Aug; 84(15):7662-7. PMID: 20484500; PMCID: PMC2897626.
    48. Opstelten W, McElhaney J, Weinberger B, Oaklander AL, Johnson RW. The impact of varicella zoster virus: chronic pain. J Clin Virol. 2010 May; 48 Suppl 1:S8-13. PMID: 20510265.
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    49. Gijzen K, Liu WM, Visontai I, Oftung F, van der Werf S, Korsvold GE, Pronk I, Aaberge IS, Tütto A, Jankovics I, Jankovics M, Gentleman B, McElhaney JE, Soethout EC. Standardization and validation of assays determining cellular immune responses against influenza. Vaccine. 2010 Apr 26; 28(19):3416-22. PMID: 20206285.
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    50. McElhaney JE. Herpes zoster: a common disease that can have a devastating impact on patients' quality of life. Expert Rev Vaccines. 2010 Mar; 9(3 Suppl):27-30. PMID: 20192715.
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    51. Deans GD, Stiver HG, McElhaney JE. Influenza vaccines provide diminished protection but are cost-saving in older adults. J Intern Med. 2010 Feb; 267(2):220-7. PMID: 20175868.
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    52. Mui TS, Man JM, McElhaney JE, Sandford AJ, Coxson HO, Birmingham CL, Li Y, Man SF, Sin DD. Telomere length and chronic obstructive pulmonary disease: evidence of accelerated aging. J Am Geriatr Soc. 2009 Dec; 57(12):2372-4. PMID: 20122000.
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    53. Johnson RW, McElhaney J. Postherpetic neuralgia in the elderly. Int J Clin Pract. 2009 Sep; 63(9):1386-91. PMID: 19691624; PMCID: PMC2779987.
    54. McElhaney JE, Effros RB. Immunosenescence: what does it mean to health outcomes in older adults? Curr Opin Immunol. 2009 Aug; 21(4):418-24. PMID: 19570667; PMCID: PMC2725188.
    55. Monto AS, Ansaldi F, Aspinall R, McElhaney JE, Montaño LF, Nichol KL, Puig-Barberà J, Schmitt J, Stephenson I. Influenza control in the 21st century: Optimizing protection of older adults. Vaccine. 2009 Aug 13; 27(37):5043-53. PMID: 19559118.
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    56. McElhaney JE. Prevention of infectious diseases in older adults through immunization: the challenge of the senescent immune response. Expert Rev Vaccines. 2009 May; 8(5):593-606. PMID: 19397416.
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    57. McElhaney JE, Ewen C, Zhou X, Kane KP, Xie D, Hager WD, Barry MB, Kleppinger A, Wang Y, Bleackley RC. Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults. Vaccine. 2009 Apr 21; 27(18):2418-25. PMID: 19368783; PMCID: PMC2800816.
    58. Sambhara S, McElhaney JE. Immunosenescence and influenza vaccine efficacy. Curr Top Microbiol Immunol. 2009; 333:413-29. PMID: 19768417.
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    59. Falsey AR, Walsh EE, Capellan J, Gravenstein S, Zambon M, Yau E, Gorse GJ, Edelman R, Hayden FG, McElhaney JE, Neuzil KM, Nichol KL, Simões EA, Wright PF, Sales VM. Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individuals. J Infect Dis. 2008 Nov 1; 198(9):1317-26. PMID: 18855558.
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    60. Rimmelzwaan GF, McElhaney JE. Correlates of protection: novel generations of influenza vaccines. Vaccine. 2008 Sep 12; 26 Suppl 4:D41-4. PMID: 19230158.
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    61. McElhaney JE, Dutz JP. Better influenza vaccines for older people: what will it take? J Infect Dis. 2008 Sep 1; 198(5):632-4. PMID: 18652548.
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    62. Leng SX, McElhaney JE, Walston JD, Xie D, Fedarko NS, Kuchel GA. ELISA and multiplex technologies for cytokine measurement in inflammation and aging research. J Gerontol A Biol Sci Med Sci. 2008 Aug; 63(8):879-84. PMID: 18772478; PMCID: PMC2562869.
    63. Effros RB, Austad S, Blau H, Chesselet MF, Ingram D, Johnson TE, Kaeberlein M, Lundblad V, McCarter R, McElhaney J, Saag M. The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America. J Gerontol A Biol Sci Med Sci. 2008 Apr; 63(4):331-7. PMID: 18426956.
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    64. Rudolph JL, Ramlawi B, Kuchel GA, McElhaney JE, Xie D, Sellke FW, Khabbaz K, Levkoff SE, Marcantonio ER. Chemokines are associated with delirium after cardiac surgery. J Gerontol A Biol Sci Med Sci. 2008 Feb; 63(2):184-9. PMID: 18314455; PMCID: PMC2735245.
    65. Johnson R, McElhaney J, Pedalino B, Levin M. Prevention of herpes zoster and its painful and debilitating complications. Int J Infect Dis. 2007 Nov; 11 Suppl 2:S43-8. PMID: 18162246.
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    66. LaForce C, Man CY, Henderson FW, McElhaney JE, Hampel FC, Bettis R, Kudule L, Harris J, Yates P, Tisdale M, Webster A. Efficacy and safety of inhaled zanamivir in the prevention of influenza in community-dwelling, high-risk adult and adolescent subjects: a 28-day, multicenter, randomized, double-blind, placebo-controlled trial. Clin Ther. 2007 Aug; 29(8):1579-90; discussion 1577-8. PMID: 17919541.
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    67. Xie D, McElhaney JE. Lower GrB+ CD62Lhigh CD8 TCM effector lymphocyte response to influenza virus in older adults is associated with increased CD28null CD8 T lymphocytes. Mech Ageing Dev. 2007 May-Jun; 128(5-6):392-400. PMID: 17570460; PMCID: PMC2169430.
    68. McElhaney JE, Xie D, Hager WD, Barry MB, Wang Y, Kleppinger A, Ewen C, Kane KP, Bleackley RC. T cell responses are better correlates of vaccine protection in the elderly. J Immunol. 2006 May 15; 176(10):6333-9. PMID: 16670345.
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    69. McElhaney JE, Goel V, Toane B, Hooten J, Shan JJ. Efficacy of COLD-fX in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blinded, placebo controlled trial. J Altern Complement Med. 2006 Mar; 12(2):153-7. PMID: 16566675.
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    70. Gravenstein S, Drinka P, Osterweil D, Schilling M, Krause P, Elliott M, Shult P, Ambrozaitis A, Kandel R, Binder E, Hammond J, McElhaney J, Flack N, Daly J, Keene O. Inhaled zanamivir versus rimantadine for the control of influenza in a highly vaccinated long-term care population. J Am Med Dir Assoc. 2005 Nov-Dec; 6(6):359-66. PMID: 16286056.
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    71. McElhaney JE. The unmet need in the elderly: designing new influenza vaccines for older adults. Vaccine. 2005 Jul 8; 23 Suppl 1:S10-25. PMID: 15908062.
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    72. McElhaney JE, Hooton JW, Hooton N, Bleackley RC. Comparison of single versus booster dose of influenza vaccination on humoral and cellular immune responses in older adults. Vaccine. 2005 May 9; 23(25):3294-300. PMID: 15837235.
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    73. Costanzo ES, Lutgendorf SK, Kohut ML, Nisly N, Rozeboom K, Spooner S, Benda J, McElhaney JE. Mood and cytokine response to influenza virus in older adults. J Gerontol A Biol Sci Med Sci. 2004 Dec; 59(12):1328-33. PMID: 15699534.
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    74. Kohut ML, Arntson BA, Lee W, Rozeboom K, Yoon KJ, Cunnick JE, McElhaney J. Moderate exercise improves antibody response to influenza immunization in older adults. Vaccine. 2004 Jun 2; 22(17-18):2298-306. PMID: 15149789.
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    75. McElhaney JE, Herre JM, Lawson ML, Cole SK, Burke BL, Hooton JW. Effect of congestive heart failure on humoral and ex vivo cellular immune responses to influenza vaccination in older adults. Vaccine. 2004 Jan 26; 22(5-6):681-8. PMID: 14741160.
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    76. McElhaney JE, Gravenstein S, Cole SK, Davidson E, O'neill D, Petitjean S, Rumble B, Shan JJ. A placebo-controlled trial of a proprietary extract of North American ginseng (CVT-E002) to prevent acute respiratory illness in institutionalized older adults. J Am Geriatr Soc. 2004 Jan; 52(1):13-9. PMID: 14687309.
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    77. McElhaney JE. Overcoming the challenges of immunosenescence in the prevention of acute respiratory illness in older people. Conn Med. 2003 Sep; 67(8):469-74. PMID: 14587126.
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    78. Ewen C, Kane KP, Shostak I, Griebel PJ, Bertram EM, Watts TH, Bleackley RC, McElhaney JE. A novel cytotoxicity assay to evaluate antigen-specific CTL responses using a colorimetric substrate for Granzyme B. J Immunol Methods. 2003 May 1; 276(1-2):89-101. PMID: 12738362.
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    79. McElhaney JE. Influenza: a preventable lethal disease. J Gerontol A Biol Sci Med Sci. 2002 Oct; 57(10):M627-8. PMID: 12242313.
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    80. McElhaney JE. Nutrition, exercise, and influenza vaccination. J Gerontol A Biol Sci Med Sci. 2002 Sep; 57(9):M555-6. PMID: 12196489.
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    81. McElhaney JE, Gravenstein S, Upshaw CM, Hooton JW, Krause P, Drinka P, Bleackley RC. Granzyme B: a marker of risk for influenza in institutionalized older adults. Vaccine. 2001 Jun 14; 19(27):3744-51. PMID: 11395209.
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    82. Lawson F, Baker V, Au D, McElhaney JE. Standing orders for influenza vaccination increased vaccination rates in inpatient settings compared with community rates. J Gerontol A Biol Sci Med Sci. 2000 Sep; 55(9):M522-6. PMID: 10995050.
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    83. Cree M, Soskolne CL, Belseck E, Hornig J, McElhaney JE, Brant R, Suarez-Almazor M. Mortality and institutionalization following hip fracture. J Am Geriatr Soc. 2000 Mar; 48(3):283-8. PMID: 10733054.
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    84. Rolfson DB, McElhaney JE, Jhangri GS, Rockwood K. Validity of the confusion assessment method in detecting postoperative delirium in the elderly. Int Psychogeriatr. 1999 Dec; 11(4):431-8. PMID: 10631588.
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    85. Rolfson DB, McElhaney JE, Rockwood K, Finnegan BA, Entwistle LM, Wong JF, Suarez-Almazor ME. Incidence and risk factors for delirium and other adverse outcomes in older adults after coronary artery bypass graft surgery. Can J Cardiol. 1999 Jul; 15(7):771-6. PMID: 10411615.
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    86. McElhaney JE. Liposomal influenza vaccine: a viewpoint by Janet E. McElhaney. BioDrugs. 1999 Feb; 11(2):145-6. PMID: 18031123.
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    87. McElhaney JE, Gravenstein S, Krause P, Hooton JW, Upshaw CM, Drinka P. Assessment of markers of the cell-mediated immune response after influenza virus infection in frail older adults. Clin Diagn Lab Immunol. 1998 Nov; 5(6):840-4. PMID: 9801346; PMCID: PMC96213.
    88. McElhaney JE, Upshaw CM, Hooton JW, Lechelt KE, Meneilly GS. Responses to influenza vaccination in different T-cell subsets: a comparison of healthy young and older adults. Vaccine. 1998 Nov; 16(18):1742-7. PMID: 9778750.
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    89. McElhaney JE, Gravenstein S, Upshaw CM, Hooton JW, Krause P, Drinka P. Immune response to influenza vaccination in institutionalized elderly: effect on different T-cell subsets. Vaccine. 1998 Feb; 16(4):403-9. PMID: 9607063.
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    90. Powers DC, McElhaney JE, Florendo OA, Manning MC, Upshaw CM, Bentley DW, Wilkinson BE. Humoral and cellular immune responses following vaccination with purified recombinant hemagglutinin from influenza A (H3N2) virus. J Infect Dis. 1997 Feb; 175(2):342-51. PMID: 9203655.
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    91. McElhaney JE, Pinkoski MJ, Au D, Lechelt KE, Bleackley RC, Meneilly GS. Helper and cytotoxic T lymphocyte responses to influenza vaccination in healthy compared to diabetic elderly. Vaccine. 1996 Apr; 14(6):539-44. PMID: 8782353.
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    92. McElhaney JE, Pinkoski MJ, Upshaw CM, Bleackley RC. The cell-mediated cytotoxic response to influenza vaccination using an assay for granzyme B activity. J Immunol Methods. 1996 Mar 28; 190(1):11-20. PMID: 8601703.
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    93. Juby A, Davis P, Genge T, McElhaney J. Anticardiolipin antibodies in two elderly subpopulations. Lupus. 1995 Dec; 4(6):482-5. PMID: 8749572.
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    94. Pilarski LM, Paine D, McElhaney JE, Cass CE, Belch AR. Multidrug transporter P-glycoprotein 170 as a differentiation antigen on normal human lymphocytes and thymocytes: modulation with differentiation stage and during aging. Am J Hematol. 1995 Aug; 49(4):323-35. PMID: 7639278.
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    95. McElhaney JE, Pinkoski MJ, Meneilly GS. Changes in CD45 isoform expression vary according to the duration of T-cell memory after vaccination. Clin Diagn Lab Immunol. 1995 Jan; 2(1):73-81. PMID: 7719917; PMCID: PMC170104.
    96. McElhaney JE, Meneilly GS, Pinkoski MJ, Lechelt KE, Bleackley RC. Vaccine-related determinants of the interleukin-2 response to influenza vaccination in healthy young and elderly adults. Vaccine. 1995 Jan; 13(1):6-10. PMID: 7762279.
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    97. Garner R, Helgason CD, Atkinson EA, Pinkoski MJ, Ostergaard HL, Sorensen O, Fu A, Lapchak PH, Rabinovitch A, McElhaney JE, et al. Characterization of a granule-independent lytic mechanism used by CTL hybridomas. J Immunol. 1994 Dec 15; 153(12):5413-21. PMID: 7527440.
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    98. Juby AG, Davis P, McElhaney JE, Gravenstein S. Prevalence of selected autoantibodies in different elderly subpopulations. Br J Rheumatol. 1994 Dec; 33(12):1121-4. PMID: 8000738.
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    99. McElhaney JE, Meneilly GS, Lechelt KE, Bleackley RC. Split-virus influenza vaccines: do they provide adequate immunity in the elderly? J Gerontol. 1994 Mar; 49(2):M37-43. PMID: 8126350.
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    100. McElhaney JE, Pinkoski MJ, Meneilly GS. Changes in CD45 isoform expression after influenza vaccination. Mech Ageing Dev. 1993 Jun; 69(1-2):79-91. PMID: 8377531.
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    101. McElhaney JE, Meneilly GS, Lechelt KE, Beattie BL, Bleackley RC. Antibody response to whole-virus and split-virus influenza vaccines in successful ageing. Vaccine. 1993; 11(10):1055-60. PMID: 8212827.
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    102. McElhaney JE, Meneilly GS, Beattie BL, Helgason CD, Lee SF, Devine RD, Bleackley RC. The effect of influenza vaccination on IL2 production in healthy elderly: implications for current vaccination practices. J Gerontol. 1992 Jan; 47(1):M3-8. PMID: 1730850.
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    103. McElhaney JE, Beattie BL, Devine R, Grynoch R, Toth EL, Bleackley RC. Age-related decline in interleukin 2 production in response to influenza vaccine. J Am Geriatr Soc. 1990 Jun; 38(6):652-8. PMID: 2358627.
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    104. Bleackley RC, Horak H, McElhaney J, Havele C, Shaw AR, Turner AR, Paetkau VH. Translation of lymphocyte mRNA for mouse colony stimulating factor. Nucleic Acids Res. 1983 May 25; 11(10):3027-35. PMID: 6190128; PMCID: PMC325945.
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