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Ren-He Xu MD, PhD

TitleAssociate Professor
InstitutionUConn Health Center
DepartmentGenetics and Developmental Biology
AddressMC 6403
Cell and Genome Sciences Building, MC 6403
400 Farmington Avenue
Phone860-679-3363
Fax860-679-8345
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    Other Positions
    TitleDirector
    InstitutionUConn Health Center
    DepartmentHuman Embryonic Stem Cell Core Facility

    TitleAssociate Professor
    InstitutionUniversity of Connecticut
    DepartmentUConn Stem Cell Institute


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang X, Lazorchak AS, Song L, Li E, Zhang Z, Jiang B, Xu RH. Immune modulatory mesenchymal stem cells derived from human embryonic stem cells through a trophoblast-like stage. Stem Cells. 2016 Feb; 34(2):380-91. PMID: 26523849.
      View in: PubMed
    2. Drissi H, Gibson JD, Guzzo RM, Xu RH. Derivation and Chondrogenic Commitment of Human Embryonic Stem Cell-Derived Mesenchymal Progenitors. Methods Mol Biol. 2015; 1340:65-78. PMID: 26445831.
      View in: PubMed
    3. Guzzo RM, Scanlon V, Sanjay A, Xu RH, Drissi H. Establishment of human cell type-specific iPS cells with enhanced chondrogenic potential. Stem Cell Rev. 2014 Dec; 10(6):820-9. PMID: 24958240.
      View in: PubMed
    4. Zhang J, Huo Y, Wu H, Yu K, Kim JK, Yarish C, Qin Y, Liu C, Xu R, He P. The origin of the Ulva macroalgal blooms in the Yellow Sea in 2013. Mar Pollut Bull. 2014 Dec 15; 89(1-2):276-83. PMID: 25444626.
      View in: PubMed
    5. Wang X, Kimbrel EA, Ijichi K, Paul D, Lazorchak AS, Chu J, Kouris NA, Yavanian GJ, Lu SJ, Pachter JS, Crocker SJ, Lanza R, Xu RH. Human ESC-derived MSCs outperform bone marrow MSCs in the treatment of an EAE model of multiple sclerosis. Stem Cell Reports. 2014 Jul 8; 3(1):115-30. PMID: 25068126; PMCID: PMC4110787.
    6. Wang J, Park JW, Drissi H, Wang X, Xu RH. Epigenetic regulation of miR-302 by JMJD1C inhibits neural differentiation of human embryonic stem cells. J Biol Chem. 2014 Jan 24; 289(4):2384-95. PMID: 24318875; PMCID: PMC3900981.
    7. Guzzo RM, Gibson J, Xu RH, Lee FY, Drissi H. Efficient differentiation of human iPSC-derived mesenchymal stem cells to chondroprogenitor cells. J Cell Biochem. 2013 Feb; 114(2):480-90. PMID: 22961870.
      View in: PubMed
    8. Fei Y, Xu RH, Hurley MM. Stem cell-based bone repair. Am J Stem Cells. 2012; 1(2):106-13. PMID: 23671803; PMCID: PMC3636738.
    9. Kim C, Park J, Amano T, Xu RH, Lin G, Carter MG, Tian XC. Established preblastocyst- and blastocyst-derived ES cell lines have highly similar gene expression profiles, despite their differing requirements for derivation culture conditions. Cell Reprogram. 2012 Feb; 14(1):1-7. PMID: 22257162; PMCID: PMC3275092.
    10. Martins-Taylor K, Xu RH. Concise review: Genomic stability of human induced pluripotent stem cells. Stem Cells. 2012 Jan; 30(1):22-7. PMID: 21823210.
      View in: PubMed
    11. Martins-Taylor K, Schroeder DI, LaSalle JM, Lalande M, Xu RH. Role of DNMT3B in the regulation of early neural and neural crest specifiers. Epigenetics. 2012 Jan 1; 7(1):71-82. PMID: 22207353; PMCID: PMC3329505.
    12. Lin G, Xu RH. Progresses and challenges in optimization of human pluripotent stem cell culture. Curr Stem Cell Res Ther. 2010 Sep; 5(3):207-14. PMID: 20214560.
      View in: PubMed
    13. Zeng H, Guo M, Martins-Taylor K, Wang X, Zhang Z, Park JW, Zhan S, Kronenberg MS, Lichtler A, Liu HX, Chen FP, Yue L, Li XJ, Xu RH. Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells. PLoS One. 2010; 5(7):e11853. PMID: 20686615; PMCID: PMC2912324.
    14. Martins-Taylor K, Xu RH. Determinants of pluripotency: from avian, rodents, to primates. J Cell Biochem. 2010 Jan 1; 109(1):16-25. PMID: 19937733.
      View in: PubMed
    15. Lin G, Martins-Taylor K, Xu RH. Human embryonic stem cell derivation, maintenance, and differentiation to trophoblast. Methods Mol Biol. 2010; 636:1-24. PMID: 20336513.
      View in: PubMed
    16. Li Y, Zeng H, Xu RH, Liu B, Li Z. Vaccination with human pluripotent stem cells generates a broad spectrum of immunological and clinical responses against colon cancer. Stem Cells. 2009 Dec; 27(12):3103-11. PMID: 19816950.
      View in: PubMed
    17. Wang X, Lin G, Martins-Taylor K, Zeng H, Xu RH. Inhibition of caspase-mediated anoikis is critical for basic fibroblast growth factor-sustained culture of human pluripotent stem cells. J Biol Chem. 2009 Dec 4; 284(49):34054-64. PMID: 19828453; PMCID: PMC2797176.
    18. Zeng H, Park JW, Guo M, Lin G, Crandall L, Compton T, Wang X, Li XJ, Chen FP, Xu RH. Lack of ABCG2 expression and side population properties in human pluripotent stem cells. Stem Cells. 2009 Oct; 27(10):2435-45. PMID: 19670287.
      View in: PubMed
    19. Xu RH, Sampsell-Barron TL, Gu F, Root S, Peck RM, Pan G, Yu J, Antosiewicz-Bourget J, Tian S, Stewart R, Thomson JA. NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell. 2008 Aug 7; 3(2):196-206. PMID: 18682241; PMCID: PMC2758041.
    20. Xu RH, Peck RM, Li DS, Feng X, Ludwig T, Thomson JA. Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods. 2005 Mar; 2(3):185-90. PMID: 15782187.
      View in: PubMed
    21. Xu RH, Chen X, Li DS, Li R, Addicks GC, Glennon C, Zwaka TP, Thomson JA. BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol. 2002 Dec; 20(12):1261-4. PMID: 12426580.
      View in: PubMed
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